Zobrazeno 1 - 10
of 16 559
pro vyhledávání: '"Leopold P"'
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations
Autor:
Ananth Pallaseni, Elin Madli Peets, Gareth Girling, Luca Crepaldi, Ivan Kuzmin, Marilin Moor, Núria Muñoz-Subirana, Joost Schimmel, Özdemirhan Serçin, Balca R. Mardin, Marcel Tijsterman, Hedi Peterson, Michael Kosicki, Leopold Parts
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Repair of double-stranded breaks generated by CRISPR/Cas9 is highly dependent on the flanking DNA sequence. To learn about interactions between DNA repair and target sequence, we measure frequencies of over 236,000 distinct Cas9-generated mu
Externí odkaz:
https://doaj.org/article/fbe87db4bf6847ae8da2481704552e14
Autor:
Leopold Peiseler, Vanessa Schenker, Karin Schatzmann, Stephan Pfister, Vanessa Wood, Tobias Schmidt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lithium-ion batteries are pivotal in climate change mitigation. While their own carbon footprint raises concerns, existing studies are scattered, hard to compare and largely overlook the relevance of battery materials. Here, we go beyond tra
Externí odkaz:
https://doaj.org/article/440877baf0324b2795aecc80e54d6b1b
Autor:
Martin Novak, Vladimir Jecminek, Leopold Pleva, Marek Penhaker, Martin Schmidt, Tomas Mimra, Jan Kubicek, Martin Augustynek
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
IntroductionThe methods for diagnosing compartment syndrome non-invasively remain under debate. Bioimpedance measurements offer a promising avenue in clinical practice, detecting subtle changes in organ impedance due to volume shifts. This study expl
Externí odkaz:
https://doaj.org/article/f24fe0f7dc4142938cca16d06b47d17b
Publikováno v:
Trees, Forests and People, Vol 16, Iss , Pp 100519- (2024)
The contribution of non-timber forest products to the economy is ignored and often undervalued due to their subsistence nature. The study focused on baobab trees aiming to understand the baobab population, its asset value across various land uses, an
Externí odkaz:
https://doaj.org/article/8bf0958c5f9f4d9c87e023314dd95068
Autor:
Leopold Poljaković-Pajnik, Nataša Nikolić, Branislav Kovačević, Verica Vasić, Milan Drekić, Saša Orlović, Lazar Kesić
Publikováno v:
Insects, Vol 15, Iss 9, p 694 (2024)
Shrubs are a significant component of urban vegetation found in parks, but they experience various influences from biotic and abiotic agents, among which aphids play an important role. In this work, the effects of aphid colonisation on three shrub sp
Externí odkaz:
https://doaj.org/article/9a6b36c28e414b38ad401020d4d12d4f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The human penis transmits behaviorally important sensory information via the dorsal penile nerve, which is required for initiation and maintenance of erection. The human penis differs from the penes of other hominids. The lack of a baculum m
Externí odkaz:
https://doaj.org/article/00f49b770a634055b93e3c4e8462e16d
Publikováno v:
Environmental and Sustainability Indicators, Vol 19, Iss , Pp 100284- (2023)
Efforts to mitigate the effects of invasive plant species (IPS) have not produced the desired results due to poor adoption of land management practices developed by scientists and introduced to the community through a top-down approach. Little is kno
Externí odkaz:
https://doaj.org/article/0f2a11162dc04f1a8647430da624ec22
Publikováno v:
Next Energy, Vol 1, Iss 2, Pp 100017- (2023)
This commentary provides insights on present and future trends concerning the carbon footprint (CF) of liquid-electrolyte lithium-ion batteries (LIB). While the focus of the battery industry and policymakers was previously on reducing the cost of LIB
Externí odkaz:
https://doaj.org/article/e308c847d51a4e51af1dd20579120ae1
Autor:
Mohammed A. S. Ali, Kaspar Hollo, Tõnis Laasfeld, Jane Torp, Maris-Johanna Tahk, Ago Rinken, Kaupo Palo, Leopold Parts, Dmytro Fishman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Brightfield cell microscopy is a foundational tool in life sciences. The acquired images are prone to contain visual artifacts that hinder downstream analysis, and automatically removing them is therefore of great practical interest. Deep co
Externí odkaz:
https://doaj.org/article/7be180ec8d054da98d2d78766b4197a4
Autor:
Leopold Peiseler, Ye Lin Jun, Nicolas Schmid, Paul Waidelich, Abhishek Malhotra, Tobias S Schmidt
Publikováno v:
Environmental Research Letters, Vol 19, Iss 3, p 034025 (2024)
Radical innovations can shift the global competitiveness of entire nations. While countries typically struggle to absorb knowledge about novel technologies quickly, in which knowledge tends to be spatially sticky, an important exception is the fast c
Externí odkaz:
https://doaj.org/article/5b41dd7a852a4b23ba43088f2737e4aa