Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Leopold Koenig"'
Autor:
Uwe Marx, Enrico Accastelli, Rhiannon David, Hendrik Erfurth, Leopold Koenig, Roland Lauster, Anja Patricia Ramme, Petra Reinke, Hans-Dieter Volk, Annika Winter, Eva-Maria Dehne
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The first concepts for reproducing human systemic organismal biology in vitro were developed over 12 years ago. Such concepts, then called human- or body-on-a-chip, claimed that microphysiological systems would become the relevant technology platform
Externí odkaz:
https://doaj.org/article/749322213ef54553894134ac5bc2c221
Autor:
Leopold Koenig, Anja Patricia Ramme, Daniel Faust, Manuela Mayer, Tobias Flötke, Anna Gerhartl, Andreas Brachner, Winfried Neuhaus, Antje Appelt-Menzel, Marco Metzger, Uwe Marx, Eva-Maria Dehne
Publikováno v:
Cells, Vol 11, Iss 20, p 3295 (2022)
Significant advancements in the field of preclinical in vitro blood-brain barrier (BBB) models have been achieved in recent years, by developing monolayer-based culture systems towards complex multi-cellular assays. The coupling of those models with
Externí odkaz:
https://doaj.org/article/d684b971a00e49d182de9266e5f64ecb
Publikováno v:
Data in Brief, Vol 37, Iss , Pp 107140- (2021)
Integration-free induced pluripotent stem cells from related human donors’ exhibit great potential to the ongoing development of organ models. Blood cells from two different human donors were isolated, purified and reprogrammed into induced pluripo
Externí odkaz:
https://doaj.org/article/30606b5951f0441d8513fd0d37b7cfe8
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102327- (2021)
The integration-free iPSC lines TISSUi006-A and TISSUi007-A were generated by reprogramming blood cells with episomal vectors. The male human donors belong to a Caucasian family in which four additional family members donated and iPSC lines were gene
Externí odkaz:
https://doaj.org/article/3f0d57c6b0854d63982cdc9229c23e8e
Publikováno v:
Stem Cell Research, Vol 41, Iss , Pp - (2019)
Four integration-free iPSC lines were generated by reprogramming peripheral blood mononuclear cells with episomal vectors. All four human donors (two male and two female donors) belong to one Caucasian family within three different generations with t
Externí odkaz:
https://doaj.org/article/09a48395f5a54d2eafc3eb1858c4bd73
Autor:
Anja Patricia Ramme, Leopold Koenig, Tobias Hasenberg, Christine Schwenk, Corinna Magauer, Daniel Faust, Alexandra K Lorenz, Anna-Catharina Krebs, Christopher Drewell, Kerstin Schirrmann, Alexandra Vladetic, Grace-Chiaen Lin, Stephan Pabinger, Winfried Neuhaus, Frederic Bois, Roland Lauster, Uwe Marx, Eva-Maria Dehne
Publikováno v:
Future Science OA, Vol 5, Iss 8 (2019)
Microphysiological systems play a pivotal role in progressing toward a global paradigm shift in drug development. Here, we designed a four-organ-chip interconnecting miniaturized human intestine, liver, brain and kidney equivalents. All four organ mo
Externí odkaz:
https://doaj.org/article/8b4907e94de7419ea2fc0f71c05acb8f
Publikováno v:
Stem Cell Research, Vol 53, Iss, Pp 102327-(2021)
The integration-free iPSC lines TISSUi006-A and TISSUi007-A were generated by reprogramming blood cells with episomal vectors. The male human donors belong to a Caucasian family in which four additional family members donated and iPSC lines were gene
Publikováno v:
Stem Cell Research, Vol 41, Iss, Pp-(2019)
Four integration-free iPSC lines were generated by reprogramming peripheral blood mononuclear cells with episomal vectors. All four human donors (two male and two female donors) belong to one Caucasian family within three different generations with t
Publikováno v:
Data in Brief
Data in Brief, Vol 37, Iss, Pp 107140-(2021)
Data in Brief, Vol 37, Iss, Pp 107140-(2021)
Integration-free induced pluripotent stem cells from related human donors’ exhibit great potential to the ongoing development of organ models. Blood cells from two different human donors were isolated, purified and reprogrammed into induced pluripo
Autor:
Anja Patricia Ramme, Uwe Marx, Alexandra Vladetic, Grace-Chiaen Lin, Christine Schwenk, Roland Lauster, Kerstin Schirrmann, Leopold Koenig, Christopher Drewell, Anna-Catharina Krebs, Winfried Neuhaus, Stephan Pabinger, Tobias Hasenberg, Corinna Magauer, Eva-Maria Dehne, Frédéric Y. Bois, Alexandra Lorenz, Daniel Faust
Microphysiological systems are fundamental for progressing towards a global paradigm shift in drug development through the generation of patient-on-a-chip models. An increasing number of single- and multi-organ systems have been adopted by the pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43bce61eea3cc72e40489784072de53
https://doi.org/10.1101/376970
https://doi.org/10.1101/376970