Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leopold Garnar-Wortzel"'
Autor:
Leopold Garnar-Wortzel, Timothy R. Bishop, Seiya Kitamura, Natalia Milosevich, Joshua N. Asiaban, Xiaoyu Zhang, Qinheng Zheng, Emily Chen, Anissa R. Ramos, Christopher J. Ackerman, Eric N. Hampton, Arnab K. Chatterjee, Travis S. Young, Mitchell V. Hull, K. Barry Sharpless, Benjamin F. Cravatt, Dennis W. Wolan, Michael A. Erb
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 815-830 (2021)
Externí odkaz:
https://doaj.org/article/097fa2b7ad3f4a1fa4c7766ad3a5dcd3
Autor:
John A. Martignetti, Olga Camacho-Vanegas, Nolan Priedigkeit, Catalina Camacho, Elena Pereira, Li Lin, Leopold Garnar-Wortzel, Dagny Miller, Bojan Losic, Hardik Shah, Jun Liao, Jian Ma, Pratik Lahiri, Mark Chee, Eric Schadt, Peter Dottino
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 1, Pp 97-103 (2014)
Retrospective studies have demonstrated that nearly 50% of patients with ovarian cancer with normal cancer antigen 125 (CA125) levels have persistent disease; however, prospectively distinguishing between patients is currently impossible. Here, we de
Externí odkaz:
https://doaj.org/article/e663291f25024bdbb6f4e397597a489e
Autor:
Elena Pereira, Olga Camacho-Vanegas, Sanya Anand, Robert Sebra, Sandra Catalina Camacho, Leopold Garnar-Wortzel, Navya Nair, Erin Moshier, Melissa Wooten, Andrew Uzilov, Rong Chen, Monica Prasad-Hayes, Konstantin Zakashansky, Ann Marie Beddoe, Eric Schadt, Peter Dottino, John A Martignetti
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145754 (2015)
BACKGROUND:High-grade serous ovarian and endometrial cancers are the most lethal female reproductive tract malignancies worldwide. In part, failure to treat these two aggressive cancers successfully centers on the fact that while the majority of pati
Externí odkaz:
https://doaj.org/article/9c3dffebfa4d46e4b9673bbaa1836c2f
Autor:
Timothy R. Bishop, Chitra Subramanian, Eric M. Bilotta, Leopold Garnar-Wortzel, Anissa R. Ramos, Yuxiang Zhang, Joshua N. Asiaban, Christopher J. Ott, Charles O. Rock, Michael A. Erb
Publikováno v:
Nature Chemical Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec5c2ad39ec158673e4d01a6bc14fa1d
https://doi.org/10.1038/s41589-023-01320-7
https://doi.org/10.1038/s41589-023-01320-7
Autor:
Timothy R. Bishop, Chitra Subramanian, Eric M. Bilotta, Leopold Garnar-Wortzel, Anissa R. Ramos, Yuxiang Zhang, Joshua N. Asiaban, Christopher J. Ott, Charles O. Rock, Michael A. Erb
Histone acetyltransferases (HAT) catalyze the acylation of lysine side chains and are implicated in diverse human cancers as both oncogenes and non-oncogene dependencies1. Acetyl-CoA-competitive HAT inhibitors have garnered attention as potential can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80daad5d44741129f785d87ab0a83e0c
https://doi.org/10.1101/2022.08.12.503669
https://doi.org/10.1101/2022.08.12.503669
Autor:
Benjamin F. Cravatt, Qinheng Zheng, Leopold Garnar-Wortzel, Eric N. Hampton, Seiya Kitamura, Anissa R. Ramos, Michael A. Erb, Joshua N. Asiaban, Natalia Milosevich, K. Barry Sharpless, Xiaoyu Zhang, Emily Chen, Travis S. Young, Timothy R. Bishop, Arnab K. Chatterjee, Christopher J. Ackerman, Dennis W. Wolan, Mitchell V. Hull
Transcriptional co-regulators, which mediate chromatin-dependent transcriptional signaling, represent tractable targets to modulate tumorigenic gene expression programs with small molecules. Genetic loss-of-function studies have recently implicated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d4cf4198bd8dc8c44f5702413eca61
https://doi.org/10.1101/2020.12.01.406694
https://doi.org/10.1101/2020.12.01.406694
Autor:
Bojan Losic, Leopold Garnar-Wortzel, Li Lin, Jun Liao, Peter Dottino, Mark S. Chee, Nolan Priedigkeit, Pratik Lahiri, Elena Pereira, Jian Ma, Dagny Miller, Hardik Shah, John A. Martignetti, Catalina Camacho, Olga Camacho-Vanegas, Eric E. Schadt
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 1, Pp 97-103 (2014)
Retrospective studies have demonstrated that nearly 50% of patients with ovarian cancer with normal cancer antigen 125 (CA125) levels have persistent disease; however, prospectively distinguishing between patients is currently impossible. Here, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b91dca1927868265bda4431ad5faeb
http://www.sciencedirect.com/science/article/pii/S1476558614800092
http://www.sciencedirect.com/science/article/pii/S1476558614800092
Autor:
Rhonda R. McCartney, Dakshayini G. Chandrashekarappa, Leopold Garnar-Wortzel, Martin C. Schmidt
Publikováno v:
Biochimica et biophysica acta. 1864(11)
The AMP-activated protein kinase is a metabolic regulator that transduces information about energy and nutrient availability. In yeast, the AMP-activated protein kinase, called Snf1, is activated when energy and nutrients are scarce. Earlier studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6a3417b54367f9904f181e33632638
https://pubmed.ncbi.nlm.nih.gov/27524664
https://pubmed.ncbi.nlm.nih.gov/27524664
Autor:
John A. Martignetti, Elena Pereira, Olga Camacho-Vanegas, Erin Moshier, Navya Nair, Eric E. Schadt, Leopold Garnar-Wortzel, Sanya Anand, Sandra Catalina Camacho, Ann Marie Beddoe, Peter Dottino, Andrew V. Uzilov, Melissa Wooten, Monica Prasad-Hayes, Rong Chen, Robert Sebra, K. Zakashansky
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0145754 (2015)
PLoS ONE, Vol 10, Iss 12, p e0145754 (2015)
BACKGROUND:High-grade serous ovarian and endometrial cancers are the most lethal female reproductive tract malignancies worldwide. In part, failure to treat these two aggressive cancers successfully centers on the fact that while the majority of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a9c80200aab3266ab4ce216cb51030
https://doi.org/10.1016/j.ygyno.2016.04.036
https://doi.org/10.1016/j.ygyno.2016.04.036