Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Leopold Comoe"'
Autor:
Monique Zeches, Leopold Comoe, Louisette Le Men-Olivier, Eric Couillerot, Pascal Molinatti, Catherine Caron, Jean-Claude Jardillier, Jean-Claude Chénieux, Jean-Claude Audran
Publikováno v:
Phytochemistry. 37:425-428
In vitro cell culture of Fagara zanthoxyloides is reported for the first time. The cell suspension cultures produced fagaronine, but the production of this metabolite was lost after several subcultures, whereas furoquinoline accumulation remained hig
Publikováno v:
Cytometry. 11:888-893
The growth fraction, estimated by the monoclonal antibody Ki-67 labeling, and DNA content, assessed by ethidium bromide staining, were determined simultaneously in K562 leukemic cells by flow cytometry. A multiparametric analysis enabled the fraction
Autor:
Annette K. Larsen, Jean-François Riou, Leopold Comoe, Jeannine Couprie, Lucile Grondard, Bernard Desoize, Jean-Claude Jardillier
Publikováno v:
Biochemical pharmacology. 46(8)
The antileukemic alkaloid, fagaronine, is a potent differentiation inducer of various hematopoietic cell lines. We show here that fagaronine is a DNA base-pair intercalator with a K(app) of 2.1 x 10(5) M-1 for calf thymus DNA. Fagaronine inhibits the
Autor:
Pierre Jeannesson, Chantal Trentesaux, Jean-Claude Jardillier, Bernard Desoize, Leopold Comoe
Publikováno v:
Leukemia research. 11(5)
In view of new antitumor compounds which could exert their therapeutic effect through a combination of cell growth inhibition and cell maturation, we describe here the effects of a novel antileukemic alkaloid, fagaronine, on the growth and the induct
Publikováno v:
Cancer immunology, immunotherapy : CII. 30(5)
Little is known about membrane target antigens for natural killer (NK) cells. Transferrin receptor and CD15 antigen might be two of these target structures. A novel antileukemic alkaloid, fagaronine, is able to induce hemoglobin synthesis in the K562