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of 6
pro vyhledávání: '"Leontine I van der Wel"'
Autor:
Jon D. Laman, M. C. M. Verschuren, Errol P. Prens, Leslie van der Fits, Leontine I van der Wel
Publikováno v:
Journal of Pathology, 199, 107-114. John Wiley & Sons Ltd.
Psoriasis is a T-cell-mediated inflammatory skin disease. A Th1 cytokine profile with increased levels of interferon-gamma (IFN-gamma) is predominant in skin and peripheral blood mononuclear cells (PBMCs) from psoriasis patients. Furthermore, psoriat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6434b3dcd14b7202897724359de3969c
https://hdl.handle.net/1765/64387
https://hdl.handle.net/1765/64387
Publikováno v:
International Immunology. 14:669-676
CD40 ligation by CD40 ligand(+) CD4(+) T cells has been claimed to be involved in inflammatory responses in human skin. However, these data are derived from in vitro cell culture systems and immunohistochemistry, and the mechanisms involved have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c927d9e92cf436e7355890c60ce4692
https://doi.org/10.1093/intimm/dxf033
https://doi.org/10.1093/intimm/dxf033
Publikováno v:
Journal of Interferon and Cytokine Research, 27(10), 841-846. Mary Ann Liebert Inc.
Psoriasis is a chronic inflammatory skin disease, characterized by a Th1 cytokine profile. We previously demonstrated that type I interferon (IFN-alpha/beta) signaling is activated in psoriatic skin. Type I IFNs regulate the expression of many proinf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b911359450a87154b3d27d9f9b5b76a2
https://pure.eur.nl/en/publications/539878b8-e1dd-400c-a4e1-c47469d2a1d8
https://pure.eur.nl/en/publications/539878b8-e1dd-400c-a4e1-c47469d2a1d8
Publikováno v:
Journal of Interferon & Cytokine Research; Oct2007, Vol. 27 Issue 10, p841-846, 6p
Autor:
Grietje van Dijk, Sabine Mourits, Leontine I van der Wel, Marius Kant, Errol P. Prens, Leslie van der Fits
Publikováno v:
Journal of Investigative Dermatology, 128(4), 932-938. Nature Publishing Group
Keratinocytes play a key role in innate immune responses of the skin to bacterial and viral pathogens. Viral double- stranded RNA and its synthetic analogue polyriboinosinic- polyribocytidylic acid ( poly- IC) are recognized via multiple pathways inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38946a2626cfe881a0743bba733841f5
Autor:
Leslie van der Fits, Errol P. Prens, Leontine I van der Wel, Jon D. Laman, M. C. M. Verschuren
Publikováno v:
Journal of Investigative Dermatology, 122, 51-60. Nature Publishing Group
The epidermal phenotype as observed in psoriatic skin results from inflammation and abnormal proliferation and terminal differentiation of keratinocytes. Mice deficient for interferon regulatory factor-2, a repressor of interferon signaling, display
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5214602d2e30c6a180c82c4d40de8b