Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Leonora, Buzanska"'
Autor:
Zuzanna Kuczynska, Pawan Kumar Neglur, Erkan Metin, Michal Liput, Marzena Zychowicz, Valery Zayat, Natalia E. Krześniak, Leonora Buzanska, Marta Kot
Publikováno v:
Folia Neuropathologica, Vol 62, Iss 1, Pp 32-46 (2024)
Human induced pluripotent stem cells (hiPSCs) are a potential source of somatic cells for cell therapies due to their ability to self-renew and differentiate into various cells of the body. To date, the clinical application of hiPSCs has been limited
Externí odkaz:
https://doaj.org/article/4753d037bcb6466b862fca68646726d5
Autor:
Leonora Buzanska
This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to
Publikováno v:
Cells, Vol 12, Iss 3, p 390 (2023)
The formation of embryoid bodies (EBs) from human pluripotent stem cells resembles the early stages of human embryo development, mimicking the organization of three germ layers. In our study, EBs were tested for their vulnerability to chronic exposur
Externí odkaz:
https://doaj.org/article/51ccfc2f4d204bec924fb768e5373a2b
Autor:
Valery Zayat, Zuzanna Kuczynska, Michal Liput, Erkan Metin, Sylwia Rzonca-Niewczas, Marta Smyk, Tomasz Mazurczak, Alicja Goszczanska-Ciuchta, Pawel Leszczynski, Dorota Hoffman-Zacharska, Leonora Buzanska
Publikováno v:
Cells, Vol 12, Iss 2, p 339 (2023)
Dravet syndrome (DRVT) is a rare form of neurodevelopmental disorder with a high risk of sudden unexpected death in epilepsy (SUDEP), caused mainly (>80% cases) by mutations in the SCN1A gene, coding the Nav1.1 protein (alfa-subunit of voltage-sensit
Externí odkaz:
https://doaj.org/article/fda844ebb4364affb5ff16e68a9a3231
Publikováno v:
Cells, Vol 11, Iss 20, p 3234 (2022)
The hippocampus is one of the few privileged regions (neural stem cell niche) of the brain, where neural stem cells differentiate into new neurons throughout adulthood. However, dysregulation of hippocampal neurogenesis with aging, injury, depression
Externí odkaz:
https://doaj.org/article/bcd6a0d316174ce798d544e035385147
Publikováno v:
Cells, Vol 11, Iss 1, p 111 (2021)
The peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a well-known transcriptional coactivator involved in mitochondrial biogenesis. PGC-1α is implicated in the pathophysiology of many neurodegenerative disorders; therefore,
Externí odkaz:
https://doaj.org/article/2504ac8e183c4a36a5a1a102c68b4fd3
Publikováno v:
Folia Neuropathologica, Vol 55, Iss 2, Pp 110-123 (2017)
The biomimetic, standardized conditions for in vitro cultures of human neural progenitors derived from induced pluripotent stem cells (hiPSC-NPs) should meet the requirements to serve as the template and protective environment for therapeutically com
Externí odkaz:
https://doaj.org/article/595715eeedd44b6e8311522c3d53c6a5
Autor:
Ewelina Tomecka, Wioletta Lech, Marzena Zychowicz, Anna Sarnowska, Magdalena Murzyn, Tomasz Oldak, Krystyna Domanska-Janik, Leonora Buzanska, Natalia Rozwadowska
Publikováno v:
Cells, Vol 10, Iss 4, p 717 (2021)
To optimise the culture conditions for human Wharton’s jelly-derived mesenchymal stem cells (hWJ-MSCs) intended for clinical use, we investigated ten different properties of these cells cultured under 21% (atmospheric) and 5% (physiological normoxi
Externí odkaz:
https://doaj.org/article/0b61b37d60ad457b8428c949d2d36b10
Publikováno v:
Cells, Vol 11, Iss 111, p 111 (2022)
Cells
Cells
The peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a well-known transcriptional coactivator involved in mitochondrial biogenesis. PGC-1α is implicated in the pathophysiology of many neurodegenerative disorders; therefore,
Autor:
Francesca, Caloni, Olga, Introzzi, Alessandra, Caccianiga, Leonora, Buzanska, Arno C, Gutleb, Helena, Kándárova, Laura, Ceriotti, Giulia, Ranaldi, Hassan, Rashidi, Doris, Wilflingseder
Publikováno v:
ALTEX. 39(4)