Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leonor Tapias Machado"'
Autor:
Carlos Henrique Xavier, Danielle Ianzer, Fabiana Costa Fraga, Roberto Queiroga Lautner, Juliano R. Guerreiro, Leonor Tapias Machado, Andônio Carlos Martins de Camargo, Robson A.S. Santos, Elizabeth Pereira Mendes
Publikováno v:
Therapeutic Advances in Cardiovascular Disease. 5:281-295
Background: The bradykinin potentiating peptides (BPPs) are oligopeptides found in different animal venoms. BPPs isolated from Bothrops jararaca venom were the first natural inhibitors described for somatic angiotensin I-converting enzyme (ACE). They
Autor:
Danielle Ianzer, Gisele M Etelvino, Carlos Henrique Xavier, Leonor Tapias Machado, Jerusa A. Santos, Vincent Dive, B.C. Prezoto, Robson A.S. Santos, Antonio C.M. Camargo, Elizabeth Pereira Mendes
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:795-805
Angiotensin-converting enzyme (ACE) inhibitors were developed based on proline-rich oligopeptides found in the venom of Bothrops jararaca ( Bj ) previously known as bradykinin-potentiating peptides (BPPs). However, the exact mechanism of action of BP
Autor:
Renata D. Paula, Robson A.S. Santos, Leonor Tapias Machado, Raphael Faria-Silva, Maria José Campagnole-Santos, Fernanda V. Duarte, Mariana B. L. Carvalho, Beatrix Fauler
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 50(4)
We evaluated the effect of the nonpeptide mimic of angiotensin (Ang)-(1-7), AVE 0991, on the hypotensive effect of bradykinin (BK). Increasing doses of intra-arterial or intravenous BK were administered before and 30 minutes after the beginning of AV
Autor:
Leonor Tapias Machado, Robson A.S. Santos, Walkyria O. Sampaio, Raphael Faria-Silva, Ernesto L. Schiffrin, Rhian M. Touyz
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 49(1)
Angiotensin-(1-7) [Ang-(1-7)] causes endothelial-dependent vasodilation mediated, in part, by NO release. However, the molecular mechanisms involved in endothelial NO synthase (eNOS) activation by Ang-(1-7) remain unknown. Using Chinese hamster ovary