Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Leonor Rib"'
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-14 (2023)
Abstract Background For decades, the basic treatment strategies of necrotizing soft tissue infections (NSTI) have remained unchanged, primarily relying on aggressive surgical removal of infected tissue, broad-spectrum antibiotics, and supportive inte
Externí odkaz:
https://doaj.org/article/1774862a0deb4d9f8ade682396d76f1f
Autor:
Martti Maimets, Marianne Terndrup Pedersen, Jordi Guiu, Jes Dreier, Malte Thodberg, Yasuko Antoku, Pawel J. Schweiger, Leonor Rib, Raul Bardini Bressan, Yi Miao, K. Christopher Garcia, Albin Sandelin, Palle Serup, Kim B. Jensen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The small intestine forms via crosstalk between epithelial and mesenchymal cell compartments. Here, the authors show that a gradient of Wnt signalling along the anterior-posterior axis regulates Sonic Hedgehog which is required for correct formation
Externí odkaz:
https://doaj.org/article/f98ce2e90f0a4e679e2e55251af11038
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 11, p e39252 (2022)
BackgroundNecrotizing soft tissue infections (NSTIs) are complex multifactorial diseases characterized by rapid bacterial proliferation and progressive tissue death. Treatment is multidisciplinary, including surgery, broad-spectrum antibiotics, and i
Externí odkaz:
https://doaj.org/article/19748ec6df2a452791ab057ce18ade1e
Autor:
Guifen Wu, Manfred Schmid, Leonor Rib, Patrik Polak, Nicola Meola, Albin Sandelin, Torben Heick Jensen
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2387-2401.e5 (2020)
Summary: Degradation of transcripts in human nuclei is primarily facilitated by the RNA exosome. To obtain substrate specificity, the exosome is aided by adaptors; in the nucleoplasm, those adaptors are the nuclear exosome-targeting (NEXT) complex an
Externí odkaz:
https://doaj.org/article/69e703f933b043eca09cfefc47e1913a
Autor:
Leonor Rib, Dominic Villeneuve, Shilpi Minocha, Viviane Praz, Nouria Hernandez, Nicolas Guex, Winship Herr, The CycliX Consortium
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-19 (2018)
Abstract Background Compensatory liver hyperplasia—or regeneration—induced by two-thirds partial hepatectomy (PH) permits the study of synchronized activation of mammalian gene expression, particularly in relation to cell proliferation. Here, we
Externí odkaz:
https://doaj.org/article/99e6fd4387c4487894ecb6341198cddf
Autor:
William Garland, Itys Comet, Mengjun Wu, Aliaksandra Radzisheuskaya, Leonor Rib, Kristoffer Vitting-Seerup, Marta Lloret-Llinares, Albin Sandelin, Kristian Helin, Torben Heick Jensen
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1800-1811.e6 (2019)
Summary: Pluripotent embryonic stem cells (ESCs) constitute an essential cellular niche sustained by epigenomic and transcriptional regulation. Any role of post-transcriptional processes remains less explored. Here, we identify a link between nuclear
Externí odkaz:
https://doaj.org/article/223db1eaeb4a437a98c993da865c9a39
Autor:
Edyta Biskup, Brian Daniel Larsen, Leonor Rib, Lasse Folkersen, Omid Niazi, Maria R. Kamstrup, Claus Storgaard Sørensen
Publikováno v:
Cells, Vol 9, Iss 11, p 2452 (2020)
DNA-damaging cancer therapies induce interferon expression and stimulate the immune system, promoting therapy responses. The immune-activating STING (Stimulator of Interferon Genes) pathway is induced when DNA or double-stranded RNA (dsRNA) is detect
Externí odkaz:
https://doaj.org/article/76757f2848744b5f82efde858e5b6142
Autor:
Maria Margarida Teixeira, João Dias, Teresa André, Ana Joaquim, Ricardo Fernandes, Joana Magalhães, Laura Marreiros, Leonor Pinto, Leonor Ribeiro, Mafalda Nogueira, Catarina Morais
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4270-4283 (2024)
Recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a challenging disease, requiring personalized management by a multidisciplinary team. The aim of this retrospective multicentric study was to characterize real-world healthc
Externí odkaz:
https://doaj.org/article/6da25aff28154abba9f7019db9eeaecb
Autor:
Ana Varges Gomes, Gilberto Castro, Thiago Bueno de Oliveira, Ana Medina Colmenero, Leonor Ribeiro, Amanda Psyrri, Nicolas Magné, Maria Plana Serrahima, Joana Marinho, Raul Giglio, Leticia Iglesias Rey, Martín Angel, Ana M. Macedo
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionSquamous cell carcinoma of the head and neck (SCCHN) is a multifactorial disease involving genetic and environmental factors representing one of the most frequent cancer-related deaths worldwide. Tobacco and alcohol use account for most S
Externí odkaz:
https://doaj.org/article/50416f7b34e94d5d9d3fe2911ba07be2
Autor:
Kristoffer Vitting-Seerup, Mengjun Wu, Torben Heick Jensen, Aliaksandra Radzisheuskaya, Leonor Rib, Albin Sandelin, Kristian Helin, Itys Comet, William A. Garland, Marta Lloret-Llinares
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1800-1811.e6 (2019)
Cell Reports
Garland, W, Comet, I, Wu, M, Radzisheuskaya, A, Rib, L, Vitting-Seerup, K, Lloret-Llinares, M, Sandelin, A, Helin, K & Jensen, T H 2019, ' A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2 ', Cell Reports, vol. 29, no. 7, pp. 1800-1811 . https://doi.org/10.1016/j.celrep.2019.10.011
Garland, W, Comet, I, Wu, M, Radzisheuskaya, A, Rib, L, Vitting-Seerup, K, Lloret-Llinares, M, Sandelin, A, Helin, K & Jensen, T H 2019, ' A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2 ', Cell Reports, vol. 29, no. 7, pp. 1800-1811.e6 . https://doi.org/10.1016/j.celrep.2019.10.011
Cell Reports
Garland, W, Comet, I, Wu, M, Radzisheuskaya, A, Rib, L, Vitting-Seerup, K, Lloret-Llinares, M, Sandelin, A, Helin, K & Jensen, T H 2019, ' A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2 ', Cell Reports, vol. 29, no. 7, pp. 1800-1811 . https://doi.org/10.1016/j.celrep.2019.10.011
Garland, W, Comet, I, Wu, M, Radzisheuskaya, A, Rib, L, Vitting-Seerup, K, Lloret-Llinares, M, Sandelin, A, Helin, K & Jensen, T H 2019, ' A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2 ', Cell Reports, vol. 29, no. 7, pp. 1800-1811.e6 . https://doi.org/10.1016/j.celrep.2019.10.011
Summary Pluripotent embryonic stem cells (ESCs) constitute an essential cellular niche sustained by epigenomic and transcriptional regulation. Any role of post-transcriptional processes remains less explored. Here, we identify a link between nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b699a57aa8ed3d3493ca76cc207a7d78
http://www.sciencedirect.com/science/article/pii/S2211124719313117
http://www.sciencedirect.com/science/article/pii/S2211124719313117