Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leonor Morais Sarmento"'
Autor:
Marie Bonnet, Leonor Morais Sarmento, Ana C. Martins, Daniel Sobral, Joana Silva, Jocelyne Demengeot
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Developing lymphocytes express the recombination activating genes (RAGs) 1 and 2 products that form a site specific recombinase complex (RAG), introducing double strand DNA breaks (DSBs) at recombination signal sequences (RSSs) flanking the V, D, and
Externí odkaz:
https://doaj.org/article/b846fac19e7c45e09b935bbeb77373af
Autor:
Ivan Maillard, Manuel Rebelo, Ana Agua Doce, Margarida Albuquerque Almeida Santos, Jocelyne Demengeot, Alexis Dumortier, Leonor Parreira, Leonor Morais Sarmento, Warren S. Pear, Freddy Radtke, Hélia Neves
Publikováno v:
Proceedings of the National Academy of Sciences. 104:15454-15459
Notch signaling regulates B and T lymphocyte development and T cell effector class decision. In this work, we tested whether Notch activity affects mature B cell activation and differentiation to antibody-secreting cells (ASC). We show increased freq
Autor:
Vasco M. Barreto, Leonor Morais Sarmento, Marie Bonnet, Rui Gardner, Inês Trancoso, Jocelyne Demengeot, Jorge Carneiro
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 4 (2013)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Immunology, Vol 4 (2013)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Recombination-Activating Genes (RAG) 1 and 2 form the site specific recombinase that mediates V(D)J recombination, a process of DNA editing required for lymphocyte development and responsible for their diverse repertoire of antigen receptors. Mistarg