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pro vyhledávání: '"Leonila Lagunes"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1007966 (2020)
Protein activity is often regulated by ligand binding or by post-translational modifications such as phosphorylation. Moreover, proteins that are regulated in this way often contain multiple ligand binding sites or modification sites, which can opera
Externí odkaz:
https://doaj.org/article/fbea63a5a67a4e798e5de024887e67bd
Publikováno v:
Biophysical journal. 121(20)
The 20S proteasome core particle (CP) is a molecular machine that is a key component of cellular protein degradation pathways. Like other molecular machines, it is not synthesized in an active form but rather as a set of subunits that assemble into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1326af52fc826c32ad653a8bdbb78511
https://pubmed.ncbi.nlm.nih.gov/36016496
https://pubmed.ncbi.nlm.nih.gov/36016496
The 20S proteasome Core Particle (CP) is a molecular machine that is a key component of cellular protein degradation pathways. Like other molecular machines, it is not synthesized in an active form, but rather as a set of subunits that assemble into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3855f797ed28e60cf9796326c13a3dcb
https://doi.org/10.1101/2022.02.04.479176
https://doi.org/10.1101/2022.02.04.479176
Publikováno v:
PLoS Computational Biology
PLoS computational biology, vol 16, iss 8
PLoS Computational Biology, Vol 16, Iss 8, p e1007966 (2020)
PLoS computational biology, vol 16, iss 8
PLoS Computational Biology, Vol 16, Iss 8, p e1007966 (2020)
Protein activity is often regulated by ligand binding or by post-translational modifications such as phosphorylation. Moreover, proteins that are regulated in this way often contain multiple ligand binding sites or modification sites, which can opera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1c27429f035817427b754b5a3cc413
http://europepmc.org/articles/PMC7444825
http://europepmc.org/articles/PMC7444825
Autor:
Leonila Lagunes, Charles H. Lee
Publikováno v:
BIBE
Cancer treatments have been shown to be more effective if the cancer is detected and treated at an early stage. Current detection methods include imaging a tissue and blood sample testing. These methods are expensive and invasive for patients, thus s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6dc5da8a72005be88093ed37567ab70
https://doi.org/10.1109/bibe.2018.00046
https://doi.org/10.1109/bibe.2018.00046
Publikováno v:
The Journal of biological chemistry, vol 292, iss 21
Mitogen-activated protein kinase (MAPK) scaffold proteins, such as IQ motif containing GTPase activating protein 1 (IQGAP1), are promising targets for novel therapies against cancer and other diseases. Such approaches require accurate information abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e859a2e4611fd4462c61c416b3585fe
https://pubmed.ncbi.nlm.nih.gov/28396345
https://pubmed.ncbi.nlm.nih.gov/28396345