Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leonie Weckwerth"'
Autor:
Ariful Haque Abir, Leonie Weckwerth, Artur Wilhelm, Jana Thomas, Clara M. Reichardt, Luis Munoz, Simon Völkl, Uwe Appelt, Markus Mroz, Raluca Niesner, Anja Hauser, Rebecca Sophie Fischer, Katharina Pracht, Hans-Martin Jäck, Georg Schett, Gerhard Krönke, Dirk Mielenz
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101981- (2024)
Objective: The metabolism of different cells within the same microenvironment can differ and dictate physiological or pathological adaptions. Current single-cell analysis methods of metabolism are not label-free. Methods: The study introduces a label
Externí odkaz:
https://doaj.org/article/5b381a534cf04e8f9f71a6a2532ba488
Autor:
Theresa E.H. Bierling, Amelie Gumann, Shannon R. Ottmann, Sebastian R. Schulz, Leonie Weckwerth, Jana Thomas, Arne Gessner, Magdalena Wichert, Frederic Kuwert, Franziska Rost, Manuela Hauke, Tatjana Freudenreich, Dirk Mielenz, Hans-Martin Jäck, Katharina Pracht
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113739- (2024)
Summary: Glucose uptake increases during B cell activation and antibody-secreting cell (ASC) differentiation, but conflicting findings prevent a clear metabolic profile at different stages of B cell activation. Deletion of the glucose transporter typ
Externí odkaz:
https://doaj.org/article/a98e110be8b745b0865c6927784df68d
Autor:
Sebastian R. Schulz, Hans-Martin Jäck, Manfred Rauh, Tobit Steinmetz, Michael Reth, Manuela Hauke, Lena Baus, Sara Krause, Holm Schneider, Wolfgang Schuh, Patrick Morhart, Dirk Mielenz, Edith Roth, Leonie Weckwerth, Niklas Vesper, Markus Hoffmann
Publikováno v:
European Journal of Immunology
To monitor infection by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and successful vaccination against coronavirus disease 2019 (COVID‐19), the kinetics of neutralizing or blocking anti‐SARS‐CoV‐2 antibody titers need
Autor:
Sophia Urbanczyk, Olivier R. Baris, Jörg Hofmann, R. Verena Taudte, Naïg Guegen, Florian Golombek, Kathrin Castiglione, Xianyi Meng, Aline Bozec, Jana Thomas, Leonie Weckwerth, Dimitrios Mougiakakos, Sebastian R. Schulz, Wolfgang Schuh, Ursula Schlötzer-Schrehardt, Tobit D. Steinmetz, Susanne Brodesser, Rudolf J. Wiesner, Dirk Mielenz
Publikováno v:
Cell Reports
Cell Reports, 2022, 39 (10), pp.110912. ⟨10.1016/j.celrep.2022.110912⟩
Cell Reports, 2022, 39 (10), pp.110912. ⟨10.1016/j.celrep.2022.110912⟩
International audience; To elucidate the function of oxidative phosphorylation (OxPhos) during B cell differentiation, we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the mitochondrial helicase Twinkle (DNT). DNT-expressi
Publikováno v:
Arthritis & Rheumatology
Autor:
Laura Bucci, Maria V. Sokolova, Thomas Harrer, Filippo Fagni, Monika Ronneberger, K. Manger, Dirk Mielenz, Martin Herrmann, Georg Schett, Bernhard Manger, Ulrike Steffen, Axel J. Hueber, Leonie Weckwerth, Katja Schmidt, Gerhard Krönke, Arnd Kleyer, F. Schuch, David Simon, Koray Tascilar
Publikováno v:
Arthritis & Rheumatology.
OBJECTIVE: B cell depletion is an established therapeutic principle in a wide range of autoimmune diseases. However, B cells are also critical for inducing protective immunity after infection and vaccination. We undertook this study to assess humoral