Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Leonie Runtz"'
Autor:
Aliza T. Ehrlich, Meriem Semache, Florence Gross, Dillon F. Da Fonte, Leonie Runtz, Christine Colley, Amina Mezni, Christian Le Gouill, Viktoriya Lukasheva, Mireille Hogue, Emmanuel Darcq, Michel Bouvier, Brigitte L. Kieffer
Publikováno v:
iScience, Vol 14, Iss , Pp 47-57 (2019)
Summary: G protein-coupled receptors are key signaling molecules and major targets for pharmaceuticals. The concept of ligand-dependent biased signaling raises the possibility of developing drugs with improved efficacy and safety profiles, yet transl
Externí odkaz:
https://doaj.org/article/88fbd700e88446eda04c7bc96f781810
Autor:
Mireille Hogue, Christian Le Gouill, Dillon F. Da Fonte, Meriem Semache, Viktoriya Lukasheva, Aliza T. Ehrlich, Leonie Runtz, Michel Bouvier, Emmanuel Darcq, Amina Mezni, Florence Gross, Brigitte L. Kieffer, Christine Colley
Publikováno v:
iScience, Vol 14, Iss, Pp 47-57 (2019)
iScience
iScience, 2019, 14, pp.47-57. ⟨10.1016/j.isci.2019.03.011⟩
iScience
iScience, 2019, 14, pp.47-57. ⟨10.1016/j.isci.2019.03.011⟩
Summary G protein-coupled receptors are key signaling molecules and major targets for pharmaceuticals. The concept of ligand-dependent biased signaling raises the possibility of developing drugs with improved efficacy and safety profiles, yet transla
Autor:
Camille N, Pujol, Vincent, Dupuy, Martial, Séveno, Leonie, Runtz, Joël, Bockaert, Philippe, Marin, Séverine, Chaumont-Dubel
Publikováno v:
Science signaling. 13(618)
The serotonin (5-hydroxytrypatmine) receptor 5-HT
Autor:
Joël Bockaert, Martial Séveno, Leonie Runtz, Philippe Marin, Camille N. Pujol, Vincent Dupuy, Séverine Chaumont-Dubel
Publikováno v:
Science Signaling
Science Signaling, 2020, 13 (618), pp.eaax9520. ⟨10.1126/scisignal.aax9520⟩
Science Signaling, American Association for the Advancement of Science, 2020, 13 (618), pp.eaax9520. ⟨10.1126/scisignal.aax9520⟩
Science Signaling, 2020, 13 (618), pp.eaax9520. ⟨10.1126/scisignal.aax9520⟩
Science Signaling, American Association for the Advancement of Science, 2020, 13 (618), pp.eaax9520. ⟨10.1126/scisignal.aax9520⟩
International audience; The serotonin (5-hydroxytrypatmine) receptor 5-HT6 (5-HT6R) has emerged as a promising target to alleviate the cognitive symptoms of neurodevelopmental diseases. We previously demonstrated that 5-HT6R finely controls key neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f554b417770f13634411bd1ea7630436
https://hal.science/hal-02485360/file/Pujol-Sci-Signal-Final.pdf
https://hal.science/hal-02485360/file/Pujol-Sci-Signal-Final.pdf
Autor:
Frederic deBock, Alexis Fayd'herbe de Maudave, Chaitali Ghosh, Federica Bertaso, Julie Espallergues, Alexandre Milman, Leonie Runtz, Marion Toussenot, Benoit Girard, Nathalie C. Guérineau, Nicola Marchi, Jean-Marc Pascussi
Publikováno v:
Epilepsia
Epilepsia, Wiley, 2018, 59 (1), pp.123-134. ⟨10.1111/epi.13942⟩
Epilepsia, Wiley, 2018, 59 (1), pp.123-134. ⟨10.1111/epi.13942⟩
OBJECTIVE Available evidence points to a role of cytochrome P450 (Cyp) drug biotransformation enzymes in central nervous system diseases, including epilepsy. Deviations in drug pharmacokinetic profiles may impact therapeutic outcomes. Here, we ask wh
Autor:
DaWoon Park, Julie Bailly, Emmanuel Darcq, Jing-Jing Li, Arnaud Tanti, Grégory Scherrer, Natalie Del Rossi, Marie-Christine Birling, Brigitte L. Kieffer, Leonie Runtz
Publikováno v:
eNeuro
The mu-opioid receptor (MOR) modulates nociceptive pathways and reward processing, and mediates the strong analgesic and addictive properties of both medicinal as well as abused opioid drugs. MOR function has been extensively studied, and tools to ma
Autor:
Nicola Marchi, Laura Librizzi, Frédéric de Bock, Damir Janigro, Leonie Runtz, Marco de Cutis, Emmanuel L. Barbier
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2018, 667, pp.75-83. ⟨10.1016/j.neulet.2017.01.013⟩
Neuroscience Letters, Elsevier, 2018, 667, pp.75-83. ⟨10.1016/j.neulet.2017.01.013⟩
The cerebral vasculature is a complex tridimensional network of arterial and venous vessels which are anatomically in proximity of and functionally coupled to neurons. Depending on the cellular composition of the vascular wall and size, cerebral vess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f7cffbee09f450781f7e2e7aab32fa
https://hal.umontpellier.fr/hal-02071095
https://hal.umontpellier.fr/hal-02071095