Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Leonie Rouleau"'
Publikováno v:
Frontiers in bioscience (Landmark edition). 24(6)
Atherosclerosis is an inflammatory disease involving dysfunction of endothelial cells (EC) and enhanced permeability of the endothelium to oxidized low-density lipoprotein and the transmigration of monocytes from the blood to the intima where they ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcda063a74fde03be3c5f95539b07103
https://pubmed.ncbi.nlm.nih.gov/30844726
https://pubmed.ncbi.nlm.nih.gov/30844726
Autor:
Leila Jafari, Eve Langelier, Leonie Rouleau, Marc-Antoine Lauzon, Nathalie Faucheux, Hamid Hassanisaber, Olivier Drevelle, Marc-Antoine Campeau
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 98
Endothelial cell (EC) dysfunction contributes to atherosclerosis, which is associated with arterial stiffening and fibronectin (FN) deposition, by ECs and smooth muscle cells (SMCs). The effect of stiffness on the EC/FN interaction and fibrillar adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f02e3eea40111d494710e72d136106
https://pubmed.ncbi.nlm.nih.gov/30813060
https://pubmed.ncbi.nlm.nih.gov/30813060
Autor:
Frédéric Lesage, Jean-Claude Tardif, Leonie Rouleau, Mathieu Bédard, Eric Rhéaume, Pramod Avti, Ashok K. Kakkar, Tina Lam
Publikováno v:
Journal of Materials Chemistry B. 3:1788-1800
Design and synthesis of branched tetraethylene glycol (TEG) based ligands for subsequent conjugation to gold nanoshells are reported. TEG enhances the aqueous solubility of hollow gold nanoshells (HAuNShs), and the branched architecture provides stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db6634693b7d764a5baff09295ac600
https://doi.org/10.1039/c4tb01811g
https://doi.org/10.1039/c4tb01811g
Autor:
Marc-Olivier Béliveau, Eve Langelier, Leonie Rouleau, Pierrick Tremblay, Marc-Antoine Campeau, Dominic Dubé, Audrey Lortie
Publikováno v:
BioMedical Engineering
BioMedical Engineering OnLine, Vol 16, Iss 1, Pp 1-23 (2017)
BioMedical Engineering OnLine, Vol 16, Iss 1, Pp 1-23 (2017)
Background Mechanobiological studies allow the characterization of cell response to mechanical stresses. Cells need to be supported by a material with properties similar to the physiological environment. Silicone elastomers have been used to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a049ed44cba0427fe6dd5c5cf2c8644
https://doi.org/10.1186/s12938-017-0380-5
https://doi.org/10.1186/s12938-017-0380-5
Autor:
Tina Lam, Vanessa W. K. Ng, Leonie Rouleau, Jean-Claude Tardif, Pramod Avti, Frédéric Lesage, Ashok K. Kakkar, Mathieu Bédard, Eric Rhéaume
Publikováno v:
J. Mater. Chem. B. 2:6334-6344
A simple and highly versatile click chemistry based synthetic strategy to develop an ABC type miktoarm star ligand that is conjugated to gold nanoshells (GNS) is reported. The surface functionalized multifunctional GNS contain lipoic acid (LA) as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22990c87d616702c60d8984ce105cf04
https://doi.org/10.1039/c4tb00722k
https://doi.org/10.1039/c4tb00722k
Publikováno v:
Cardiovascular Pathology. 21:390-397
Background/introduction Diseases of the aorta can alter the local mechanical properties of the tissue, leading to aneurysms and plaque instability. Local tissue properties are best evaluated from surgical samples or autopsy tissue using mechanical te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e93e6cfeb77e3c1bb370664ed5865d1
https://doi.org/10.1016/j.carpath.2011.12.002
https://doi.org/10.1016/j.carpath.2011.12.002
Publikováno v:
European Journal of Pharmacology. 649:268-276
In addition to lowering cholesterol, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, have been shown to modulate gene expression in endothelial cells. The effect of statins on cell adhesion molecule expression is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6e7ea28173bd1ecfa5c29a2e3532cb
https://doi.org/10.1016/j.ejphar.2010.09.016
https://doi.org/10.1016/j.ejphar.2010.09.016
Autor:
Joanna Rossi, Leonie Rouleau, Jean-Claude Tardif, Richard L. Leask, Paul Jonak, Lisa Danielczak
Publikováno v:
Annals of Biomedical Engineering. 39:402-413
Few studies have investigated whether fluid mechanics can impair or enhance endothelial cell response to pharmacological agents such as statin drugs. We evaluated and compared Kruppel-like factor 2 (KLF2), endothelial nitric oxide synthase (eNOS), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadbeb73f026f2ebfc509365c20f5335
https://doi.org/10.1007/s10439-010-0145-9
https://doi.org/10.1007/s10439-010-0145-9
Publikováno v:
Annals of Biomedical Engineering. 38:2791-2804
Leukocytes play a pivotal role in the progression of atherosclerosis. A novel three dimensional in vitro asymmetric stenosis model was used to better investigate the role of local hemodynamics in the adhesion of leukocytes to an established plaque. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c536f4fd7b33e5f5655def28bbd29ba8
https://doi.org/10.1007/s10439-010-0032-4
https://doi.org/10.1007/s10439-010-0032-4
Autor:
Leonie, Rouleau, Romain, Berti, Vanessa W K, Ng, Carl, Matteau-Pelletier, Tina, Lam, Pierre, Saboural, Ashok K, Kakkar, Frédéric, Lesage, Eric, Rhéaume, Jean-Claude, Tardif
Publikováno v:
Contrast mediamolecular imaging. 8(1)
The development of molecular probes and novel imaging modalities, allowing better resolution and specificity, is associated with an increased potential for molecular imaging of atherosclerotic plaques especially in basic and pre-clinical research app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f67715ed02c61e3dc364cd79dbc69255
https://pubmed.ncbi.nlm.nih.gov/23109390
https://pubmed.ncbi.nlm.nih.gov/23109390