Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Leonie Ott"'
Autor:
Claudia Koch, Andra Kuske, Simon A Joosse, Gökhan Yigit, George Sflomos, Sonja Thaler, Daniel J Smit, Stefan Werner, Kerstin Borgmann, Sebastian Gärtner, Parinaz Mossahebi Mohammadi, Laura Battista, Laure Cayrefourcq, Janine Altmüller, Gabriela Salinas‐Riester, Kaamini Raithatha, Arne Zibat, Yvonne Goy, Leonie Ott, Kai Bartkowiak, Tuan Zea Tan, Qing Zhou, Michael R Speicher, Volkmar Müller, Tobias M Gorges, Manfred Jücker, Jean‐Paul Thiery, Cathrin Brisken, Sabine Riethdorf, Catherine Alix‐Panabières, Klaus Pantel
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
Abstract Functional studies giving insight into the biology of circulating tumor cells (CTCs) remain scarce due to the low frequency of CTCs and lack of appropriate models. Here, we describe the characterization of a novel CTC‐derived breast cancer
Externí odkaz:
https://doaj.org/article/6fcb45740e9c4955a376a11179160a9e
Autor:
Dominik A. Barth, Rares Drula, Leonie Ott, Linda Fabris, Ondrej Slaby, George A. Calin, Martin Pichler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Liquid biopsy—the determination of circulating cells, proteins, DNA or RNA from biofluids through a “less invasive” approach—has emerged as a novel approach in all cancer entities. Circulating non-(protein) coding RNAs including microRNAs (mi
Externí odkaz:
https://doaj.org/article/0a78656daac14bf08e48b1b93d15cf11
Autor:
Sonja Bergmann, Anja Coym, Leonie Ott, Armin Soave, Michael Rink, Melanie Janning, Malgorzata Stoupiec, Cornelia Coith, Sven Peine, Gunhild von Amsberg, Klaus Pantel, Sabine Riethdorf
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Immune checkpoint inhibition (ICI) of the PD-1/PD-L1 axis shows durable responses in a subset of patients with metastatic urothelial carcinoma (UC). However, PD-L1 expression in tumor biopsies does not necessarily correlate with response to PD-1/PD-L
Externí odkaz:
https://doaj.org/article/84e0f2d6108a43388ec7fa6acd3ac938
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Germans hesitated to get vaccinated with AstraZeneca in the COVID-19 pandemic after reports of blood clots. Methods In two preregistered online experiments with stratified randomization (Study 1 N = 824, Study 2: N = 1,056), we te
Externí odkaz:
https://doaj.org/article/32e8c063fe344c25a6ef610c7dec3a0f
Autor:
Yuanyuan Wang, Xiaobo Liu, Tobias Obser, Alexander T. Bauer, Martin Heyes, Sarah Starzonek, Mina Zulal, Karena Opitz, Leonie Ott, Sabine Riethdorf, Tobias Lange, Klaus Pantel, Gerd Bendas, Stefan W. Schneider, Marion Kusche-Gullberg, Christian Gorzelanny
Publikováno v:
Matrix Biology
Heparan sulfate (HS), a highly negatively charged glycosaminoglycan, is ubiquitously present in all tissues and also exposed on the surface of mammalian cells. A plethora of molecules such as growth factors, cytokines or coagulation factors bear HS b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1222fdcd860133dca4d62e11f77ac79a
https://hdl.handle.net/11250/3057939
https://hdl.handle.net/11250/3057939
Autor:
Nina Struve, Konstantin Hoffer, Anna-Sophie Weik, Britta Riepen, Leonie Krug, Meryem H Cetin, Jasmin Burmester, Leonie Ott, Jana Liebing, Fruzsina Gatzemeier, Justus Müller-Goebel, Mirja Gerbach, Lara Bußmann, Ann Christin Parplys, Kristian Unger, Wael Y Mansour, Ulrich Schüller, Thorsten Rieckmann, Cordula Petersen, Kai Rothkamm, Susan C Short, Malte Kriegs
Publikováno v:
Neurooncol. Adv. 4:vdab180 (2022)
Background The oncogene epidermal growth factor receptor variant III (EGFRvIII) is expressed in approximately one-third of all glioblastomas (GBMs). So far it is not clear if EGFRvIII expression induces replication stress in GBM cells, which might se
Autor:
Lena Lehrer, Lennart Hellmann, Hellen Temme, Leonie Otten, Johanna Hübenthal, Mattis Geiger, Mirjam A. Jenny, Cornelia Betsch
Publikováno v:
Journal of Health Monitoring, Vol 8, Iss S6, Pp 36-56 (2023)
Background: The German status report on climate change and health 2023 identifies numerous health risks that are caused or exacerbated by climate change. One recommendation arising from the report is to strengthen education, information, and communic
Externí odkaz:
https://doaj.org/article/f68e28e08b694a7cafdb39bd09da3924
Autor:
Zev A. Binder, Marvin Henze, Claire Faulkner, Leonie Ott, Ulrich Schüller, Jennifer J.D. Morrissette, Susan C Short, Lara Bußmann, Stephen J Bagley, Konstantin Hoffer, Donald M O Rourke, Thorsten Rieckmann, Lucy F. Stead, Malte Kriegs, Kai Rothkamm, Leonie Krug, Cordula Petersen, Kathreena M Kurian, Anna-Sophie Weik, Tim Brend, Justus Müller-Goebel, Nina Struve
Publikováno v:
Oncogene
The oncogene epidermal growth factor receptor variant III (EGFRvIII) is frequently expressed in glioblastomas (GBM) but its impact on therapy response is still under controversial debate. Here we wanted to test if EGFRvIII influences the sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a69b8243d33e19b7c68217d745061e1
Autor:
Zev A. Binder, Marvin Henze, Stephen J Bagley, Lucy F. Stead, Tim Brend, Nina Struve, Konstantin Hoffer, Thorsten Rieckmann, Claire Faulkner, Anna-Sophie Weik, Ulrich Schüller, Susan C Short, Jasmin Burmester, Leonie Ott, Ann Christin Parplys, Cordula Petersen, Malte Kriegs, Kathreena M Kurian, Kai Rothkamm, Justus Müller-Goebel, Jennifer J.D. Morrissette
Publikováno v:
Neuro Oncol
MGMT promoter methylation is the only accepted biomarker with prognostic role in GBM but its routine implementation is limited partly response to TMZ is heterogeneous, but also due to lack of effective alternative treatment options. Therefore, additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcb41bbdc8267b85159c1536b40c257
https://europepmc.org/articles/PMC6847190/
https://europepmc.org/articles/PMC6847190/
Autor:
Sabine Riethdorf, Sven Peine, Cornelia Coith, Melanie Janning, Anja Coym, Sonja Bergmann, Armin Soave, Gunhild von Amsberg, Leonie Ott, Klaus Pantel, Malgorzata Stoupiec, Michael Rink
Publikováno v:
Oncoimmunology
OncoImmunology, Vol 9, Iss 1 (2020)
OncoImmunology, Vol 9, Iss 1 (2020)
Immune checkpoint inhibition (ICI) of the PD-1/PD-L1 axis shows durable responses in a subset of patients with metastatic urothelial carcinoma (UC). However, PD-L1 expression in tumor biopsies does not necessarily correlate with response to PD-1/PD-L