Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Leonie Müller"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103032- (2024)
Summary: Many proteins self-assemble into dimers and higher-order oligomers. Therefore, the goal of this protocol is to characterize the conformational states of an endogenous protein of interest. Here, we present a protocol for assessing protein sel
Externí odkaz:
https://doaj.org/article/5f638007b99d44bd8265df1ee1c549e1
Autor:
Leonie Müller-Jensen, Samuel Knauss, Lorena Ginesta Roque, Christian Schinke, Smilla K. Maierhof, Frederik Bartels, Carsten Finke, Kristin Rentzsch, Claas Ulrich, Raphael Mohr, Werner Stenzel, Matthias Endres, Wolfgang Boehmerle, Petra Huehnchen
Publikováno v:
Data in Brief, Vol 53, Iss , Pp 110062- (2024)
The rise of cancer immunotherapy has been a milestone in clinical oncology. Above all, immune checkpoint inhibitor treatment (ICI) with monoclonal antibodies targeting programmed cell death protein 1 (PD-1), programmed cell death-ligand 1 (PD-L1), an
Externí odkaz:
https://doaj.org/article/6e49c5ff1fb645e0a9241cc6f88606f1
Autor:
Leonie Müller, Amy K Burton, Chloe L Tayler, James E Rowedder, Jonathan P Hutchinson, Simon Peace, Julie M Quayle, Melanie V Leveridge, Roland S Annan, Matthias Trost, Rachel E Peltier-Heap, Maria Emilia Dueñas
Publikováno v:
SLAS Discovery, Vol 28, Iss 1, Pp 3-11 (2023)
MALDI-TOF MS is a powerful analytical technique that provides a fast and label-free readout for in vitro assays in the high-throughput screening (HTS) environment. Here, we describe the development of a novel, HTS compatible, MALDI-TOF MS-based drug
Externí odkaz:
https://doaj.org/article/c0f8fd18f1724d62b41a5843c6740ea7
Autor:
Romane Leboutet, Céline Largeau, Leonie Müller, Magali Prigent, Grégoire Quinet, Manuel S Rodriguez, Marie-Hélène Cuif, Thorsten Hoppe, Emmanuel Culetto, Christophe Lefebvre, Renaud Legouis
Publikováno v:
eLife, Vol 12 (2023)
The ubiquitin-like proteins Atg8/LC3/GABARAP are required for multiple steps of autophagy, such as initiation, cargo recognition and engulfment, vesicle closure and degradation. Most of LC3/GABARAP functions are considered dependent on their post-tra
Externí odkaz:
https://doaj.org/article/bc2befe847e845c490254ece309a0f61
Autor:
Leonie Müller-Jensen, Samuel Knauss, Lorena Ginesta Roque, Christian Schinke, Smilla K. Maierhof, Frederik Bartels, Carsten Finke, Kristin Rentzsch, Claas Ulrich, Raphael Mohr, Werner Stenzel, Matthias Endres, Wolfgang Boehmerle, Petra Huehnchen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundNeurological immune-related adverse events (irAE-n) are severe and potentially fatal toxicities of immune checkpoint inhibitors (ICI). To date, the clinical significance of neuronal autoantibodies in irAE-n is poorly understood. Here, we ch
Externí odkaz:
https://doaj.org/article/e63286da6f3c4d12b8bfb38bedfae241
Autor:
Leonie Müller-Jensen, Sarah Zierold, Judith M Versluis, Wolfgang Boehmerle, Petra Huehnchen, Matthias Endres, Raphael Mohr, Annette Compter, Christian U Blank, Tim Hagenacker, Friedegund Meier, Lydia Reinhardt, Anja Gesierich, Martin Salzmann, Jessica C Hassel, Selma Ugurel, Lisa Zimmer, Patricia Banks, Lavinia Spain, Jennifer A Soon, Tomohiro Enokida, Makoto Tahara, Katharina C Kähler, Ruth Seggewiss-Bernhardt, Catriona Harvey, Georgina V Long, Florian Schöberl, Louisa von Baumgarten, Thomas Hundsberger, Max Schlaak, Lars E French, Samuel Knauss, Lucie M Heinzerling
Publikováno v:
Data in Brief, Vol 45, Iss , Pp 108649- (2022)
Over the past decade, cancer immunotherapy with immune checkpoint inhibitors (ICIs) has significantly improved the outcome of many malignancies. However, with the broad use of ICIs, neurological immune related adverse events (irAE) are increasingly r
Externí odkaz:
https://doaj.org/article/c91a9542a832459593f5a6f29e793e54
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Introduction: Diagnosing non-traumatic spinal cord injury (NTSCI) is often challenging. However, clear discrimination from non-spinal pathologies, e.g., “myelopathy-mimics” (MMs), is critical in preventing long-term disability and death. In this
Externí odkaz:
https://doaj.org/article/1d86830dac144643a5f3889740da2ae1
Autor:
Ina Klusmann, Sabrina Rodewald, Leonie Müller, Mascha Friedrich, Magdalena Wienken, Yizhu Li, Ramona Schulz-Heddergott, Matthias Dobbelstein
Publikováno v:
Cell Reports, Vol 17, Iss 7, Pp 1845-1857 (2016)
p53 induces cell death upon DNA damage, but this may not confer all of its tumor suppressor activity. We report that p53 activation enhances the processivity of DNA replication, as monitored by multi-label fiber assays, whereas removal of p53 reduces
Externí odkaz:
https://doaj.org/article/9105f6276edd44948086833333e81474
Publikováno v:
Journal of Paper Conservation. :1-17
The three treatment phases for pressure-sensitive tape removal included in this review are: removal of the carrier, adhesive removal from the paper surface, and adhesive removal from the paper interior. The latter process requires organic solvents. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6022407401f509b576ce24bd607feee1
https://doi.org/10.1080/18680860.2022.2060000
https://doi.org/10.1080/18680860.2022.2060000
Autor:
Romane Leboutet, Céline Largeau, Magali Prigent, Grégoire Quinet, Manuel S Rodriguez, Leonie Müller, Thorsten Hoppe, Marie-Hélène Cuif, Emmanuel Culetto, Christophe Lefebvre, Renaud Legouis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::132f584440312ba48d62feaed9fd6526
https://doi.org/10.15252/rc.2023159510
https://doi.org/10.15252/rc.2023159510
