Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leonie Gronbach"'
Autor:
Leonie Gronbach, Philipp Jurmeister, Monika Schäfer-Korting, Ulrich Keilholz, Ingeborg Tinhofer, Christian Zoschke
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
3D tumor models clearly outperform 2D cell cultures in recapitulating tissue architecture and drug response. However, their potential in understanding treatment efficacy and resistance development should be better exploited if also long-term effects
Externí odkaz:
https://doaj.org/article/a536ccfff6f943158c8516679c0220a9
Autor:
Jan F. Joseph, Leonie Gronbach, Jill García-Miller, Leticia M. Cruz, Bernhard Wuest, Ulrich Keilholz, Christian Zoschke, Maria K. Parr
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 413 (2020)
Cancer treatment often lacks individual dose adaptation, contributing to insufficient efficacy and severe side effects. Thus, personalized approaches are highly desired. Although various analytical techniques are established to determine drug levels
Externí odkaz:
https://doaj.org/article/0babc758878e48d3b14e22b49dd3e845
Autor:
Philipp Jurmeister, Leonie Gronbach, Ingeborg Tinhofer, Christian Zoschke, Monika Schäfer-Korting, U. Keilholz
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
3D tumor models clearly outperform 2D cell cultures in recapitulating tissue architecture and drug response. However, their potential in understanding treatment efficacy and resistance development should be better exploited if also long-term effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116982a966215df79c9117a0c4a3075d
https://doi.org/10.3389/fbioe.2020.579896
https://doi.org/10.3389/fbioe.2020.579896
Autor:
Monika Schäfer-Korting, Leonie Gronbach, Ulrike Alexiev, Philipp Jurmeister, Konrad Klinghammer, Ingeborg Tinhofer, Johannes Stellmacher, Christopher Wolff, Christian Zoschke, U. Keilholz
Publikováno v:
Biomaterials. 258
Pharmacotherapy of head and neck squamous cell carcinoma (HNSCC) often fails due to the development of chemoresistance and severe systemic side effects of current regimens limiting dose escalation. Preclinical models comprising all major elements of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444bf4d5dc54886e7f6dc3a42e038cb1
https://pubmed.ncbi.nlm.nih.gov/32795620
https://pubmed.ncbi.nlm.nih.gov/32795620