Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leonie Canavan"'
Autor:
Sarah E. Drummond, Robin O'Flaherty, Deirdre Edge, Ken D. O'Halloran, Leonie Canavan, Jane Rowland, Dervla O'Malley, David P. Burns, Molly Brannock
Publikováno v:
The Journal of Physiology. 596:5175-5197
Key points Impaired ventilatory capacity and diaphragm muscle weakness are prominent features of Duchenne muscular dystrophy, with strong evidence of attendant systemic and muscle inflammation. We performed a 2-week intervention in young wild-type an
Autor:
Dervla O'Malley, Molly Brannock, Kevin H. Murphy, David P. Burns, Leonie Canavan, Jane Rowland, Deirdre Edge, Ken D. O'Halloran
Publikováno v:
Experimental Physiology. 102:1177-1193
The mdx mouse model of Duchenne muscular dystrophy (DMD) shows evidence of impaired pharyngeal dilator muscle function. We hypothesised that inflammatory and stress-related factors are implicated in airway dilator muscle dysfunction. Six week old mdx
Autor:
David P, Burns, Jane, Rowland, Leonie, Canavan, Kevin H, Murphy, Molly, Brannock, Dervla, O'Malley, Ken D, O'Halloran, Deirdre, Edge
Publikováno v:
Experimental physiology. 102(9)
What is the central question of this study? We previously reported impaired upper airway dilator muscle function in the mdx mouse model of Duchenne muscular dystrophy (DMD). Our aim was to assess the effect of blocking interleukin-6 receptor signalli