Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Leonie Bluhm"'
Autor:
Lucie Heinzerling, Lisa Zimmer, Ralf Gutzmer, Andrea Forschner, Elisabeth Livingstone, Bastian Schilling, Selma Ugurel, Peter Mohr, Thilo Gambichler, Patrick Terheyden, Sebastian Haferkamp, Dirk Debus, Rudolf Herbst, Carmen Loquai, Frank Meiss, Carsten Weishaupt, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal, Maike Trommer, Jürgen Christian Becker, Ulrike Leiter, Cindy Franklin, Christoffer Gebhardt, Katharina Kahler, Leonie Bluhm, Imke Grimmelmann, Marlene Garzarolli, Dorothee Nashan, Michael Sachse, Julia Welzel, Gerhard Weyandt, Susanne Horn, Fabian Ziller, Harald Löffler, Stephan Grabbe, Gaston Schley, Georg Lodde, Jan-Malte Placke, Anca Sindrilaru
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Despite the availability of effective systemic therapies, a significant number of advanced melanoma patients develops brain metastases. This study investigated differences in incidence and time to diagnosis of brain metastasis and survival
Externí odkaz:
https://doaj.org/article/78c357556a7d4fdbba1d2ae0e5644ffc
Autor:
Dirk Schadendorf, Lucie Heinzerling, Lisa Zimmer, Ralf Gutzmer, Alexander Kreuter, Andrea Forschner, Elisabeth Livingstone, Selma Ugurel, Alexander Roesch, Peter Mohr, Thilo Gambichler, Patrick Terheyden, Sebastian Haferkamp, Friedegund Meier, Claudia Pfoehler, Dirk Debus, Rudolf Herbst, Frank Meiss, Carsten Weishaupt, Jochen Utikal, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal, Maike Trommer, Ulrike Leiter, Kerstin Schatton, Cindy Franklin, Leonie Bluhm, Imke Grimmelmann, Marlene Garzarolli, Dorothee Nashan, Michael Sachse, Julia Welzel, Gerhard Weyandt, Eren Celik, Iris Helfrich, Susanne Horn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/31d907c2fd3a4ebe9ebbc4ec2bbec6d3
Autor:
Svenja Schneegans, Lelia Lück, Katharina Besler, Leonie Bluhm, Julia‐Christina Stadler, Janina Staub, Rüdiger Greinert, Beate Volkmer, Mikael Kubista, Christoffer Gebhardt, Alexander Sartori, Darryl Irwin, Elina Serkkola, Taija afHällström, Evi Lianidou, Markus Sprenger‐Haussels, Melanie Hussong, Peter Mohr, Stefan W. Schneider, Jonathan Shaffer, Klaus Pantel, Harriet Wikman
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1001-1015 (2020)
The combination of liquid biomarkers from a single blood tube can provide more comprehensive information on tumor development and progression in cancer patients compared to single analysis. Here, we evaluated whether a combined analysis of circulatin
Externí odkaz:
https://doaj.org/article/9e3df0b98bd64b93a6f200e8ad0438b0
Autor:
Lisa Zimmer, Julia Vaubel, Peter Mohr, Axel Hauschild, Jochen Utikal, Jan Simon, Claus Garbe, Rudolf Herbst, Alexander Enk, Eckhart Kämpgen, Elisabeth Livingstone, Leonie Bluhm, Rainer Rompel, Klaus G Griewank, Michael Fluck, Bastian Schilling, Dirk Schadendorf
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118564 (2015)
Up to 50% of patients with uveal melanoma (UM) develop metastatic disease with limited treatment options. The immunomodulating agent ipilimumab has shown an overall survival (OS) benefit in patients with cutaneous metastatic melanoma in two phase III
Externí odkaz:
https://doaj.org/article/2ff3e96d807047c3a0d2ce8d8353dfe0
Autor:
Cindy Franklin, Peter Mohr, Leonie Bluhm, Friedegund Meier, Marlene Garzarolli, Michael Weichenthal, Katharina Kähler, Imke Grimmelmann, Ralf Gutzmer, Jochen Utikal, Patrick Terheyden, Rudolf Herbst, Sebastian Haferkamp, Claudia Pfoehler, Andrea Forschner, Ulrike Leiter, Fabian Ziller, Frank Meiss, Jens Ulrich, Alexander Kreuter, Christoffer Gebhardt, Julia Welzel, Bastian Schilling, Martin Kaatz, Karin Scharfetter-Kochanek, Edgar Dippel, Dorothee Nashan, Michael Sachse, Carsten Weishaupt, Harald Löffler, Thilo Gambichler, Carmen Loquai, Lucie Heinzerling, Stephan Grabbe, Dirk Debus, Gaston Schley, Jessica C Hassel, Gerhard Weyandt, Maike Trommer, Georg Lodde, Jan-Malte Placke, Lisa Zimmer, Elisabeth Livingstone, Jürgen Christian Becker, Susanne Horn, Dirk Schadendorf, Selma Ugurel
BackgroundDespite the availability of effective systemic therapies, a significant number of advanced melanoma patients develops brain metastases. This study investigated differences in incidence and time to diagnosis of brain metastasis and survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861f61bac67444b59bcad9028154c312
https://www.ncbi.nlm.nih.gov/pubmed/37028819
https://www.ncbi.nlm.nih.gov/pubmed/37028819
Autor:
Peter Mohr, Klaus Pantel, Janina Staub, Harriet Wikman, Taija af Hällström, Julia-Christina Stadler, Stefan W. Schneider, Svenja Schneegans, Alexander Sartori, Evi Lianidou, Leonie Bluhm, Mikael Kubista, Jonathan M Shaffer, Darryl Irwin, Katharina Besler, Rüdiger Greinert, Elina Serkkola, Lelia Lück, Beate Volkmer, Christoffer Gebhardt, Melanie A. Hussong, Markus Sprenger-Haussels
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1001-1015 (2020)
Molecular Oncology
Molecular Oncology
The combination of liquid biomarkers from a single blood tube can provide more comprehensive information on tumor development and progression in cancer patients compared to single analysis. Here, we evaluated whether a combined analysis of circulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c582f63d246ccd3c1874b95ade0b3cd
https://doi.org/10.1002/1878-0261.12669
https://doi.org/10.1002/1878-0261.12669
Autor:
Cindy Franklin, Peter Mohr, Leonie Bluhm, Imke Grimmelmann, Ralf Gutzmer, Friedegund Meier, Marlene Garzarolli, Michael Weichenthal, Claudia Pfoehler, Rudolf Herbst, Patrick Terheyden, Jochen Utikal, Jens Ulrich, Dirk Debus, Sebastian Haferkamp, Martin Kaatz, Andrea Forschner, Ulrike Leiter, Dorothee Nashan, Alexander Kreuter, Michael Sachse, Julia Welzel, Lucie Heinzerling, Frank Meiss, Carsten Weishaupt, Thilo Gambichler, Gerhard Weyandt, Edgar Dippel, Kerstin Schatton, Eren Celik, Maike Trommer, Iris Helfrich, Alexander Roesch, Lisa Zimmer, Elisabeth Livingstone, Dirk Schadendorf, Susanne Horn, Selma Ugurel
BackgroundDespite of various therapeutic strategies, treatment of patients with melanoma brain metastasis (MBM) still is a major challenge. This study aimed at investigating the impact of type and sequence of immune checkpoint blockade (ICB) and targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5519484349bebf81daf5185566cd603d
https://www.ncbi.nlm.nih.gov/pubmed/35688555
https://www.ncbi.nlm.nih.gov/pubmed/35688555
Autor:
Dirk Schadendorf, Carmen Loquai, Felix Kiecker, Konstantin Drexler, Laura Susok, Peter Mohr, Katharina C. Kähler, Leonie Bluhm, Lydia Reinhardt, Friedegund Meier, Jessica C. Hassel, Selma Ugurel, Claudia Pföhler, Sarah Knispel, Bastian Schilling, Christopher G. Cann, Simone M. Goldinger, Elisabeth Livingstone, Andreas Stang, Thomas Eigentler, Cindy Franklin, Julia K. Tietze, Maria Isabel Fleischer, Carola Berking, Paolo A. Ascierto, Judith Sirokay, Carsten Weishaupt, Patrick Schummer, Lisa Zimmer, Georgina V. Long, Maximilian Gassenmaier, Carina N. Owen, Lucie Heinzerling, Raphael R. Reinhard, Douglas B. Johnson, Kai Martin Thoms, Alexander M. Menzies, Dennis Niebel, Ralf Gutzmer
Publikováno v:
European journal of cancer (Oxford, England : 1990). 148
Background Elevated lactate dehydrogenase (LDH) is a known predictive and prognostic factor for a poor outcome in patients with metastatic melanoma. It is unclear whether first-line targeted therapy (TT) or immune checkpoint inhibition (ICI) is more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7b5b295efc1524ab0bf2996f38c02f
https://pubmed.ncbi.nlm.nih.gov/33735811
https://pubmed.ncbi.nlm.nih.gov/33735811
Autor:
Klaus Pantel, Janina Staub, Harriet Wikman, Peter Mohr, Jonathan M Shaffer, Melanie Hussong, Alexander Sartori, Stefan W. Schneider, Leonie Bluhm, Svenja Schneegans, Lelia Lück, Rüdiger Greinert, Markus Sprenger-Haussels, Taija af Hällström, Darryl Irwin, Beate Volkmer
Publikováno v:
Cancer Research. 78:5596-5596
Liquid biopsy represents a powerful clinical tool that makes use of the detection of circulating tumor cells (CTCs), circulating tumor DNA (ctDNA) and exosomes in peripheral blood. Each different analysis is complementary to each other and can give a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6802470cd140fc55260d477fd6e1290
https://doi.org/10.1158/1538-7445.am2018-5596
https://doi.org/10.1158/1538-7445.am2018-5596
Autor:
Peter Mohr, Jochen Utikal, Bastian Schilling, Alexander Enk, Lisa Zimmer, Jan C. Simon, Rudolf A. Herbst, Klaus G. Griewank, Leonie Bluhm, Axel Hauschild, Elisabeth Livingstone, Dirk Schadendorf, Rainer Rompel, Eckhart Kämpgen, Michael Fluck, Julia Vaubel, Claus Garbe
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118564 (2015)
PLoS ONE
PLoS ONE
Purpose Up to 50% of patients with uveal melanoma (UM) develop metastatic disease with limited treatment options. The immunomodulating agent ipilimumab has shown an overall survival (OS) benefit in patients with cutaneous metastatic melanoma in two p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65f88516d949b9fbab4bfe734d4e5e6
http://europepmc.org/articles/PMC4356548?pdf=render
http://europepmc.org/articles/PMC4356548?pdf=render