Výsledky vyhledávání - "Leonie, de Boer"

Akademický článek

CalcAMP: A New Machine Learning Model for the Accurate Prediction of Antimicrobial Activity of Peptides

Autor: Colin Bournez, Martijn Riool, Leonie de Boer, Robert A. Cordfunke, Leonie de Best, Remko van Leeuwen, Jan Wouter Drijfhout, Sebastian A. J. Zaat, Gerard J. P. van Westen

Publikováno v: Antibiotics, Vol 12, Iss 4, p 725 (2023)

To combat infection by microorganisms host organisms possess a primary arsenal via the innate immune system. Among them are defense peptides with the ability to target a wide range of pathogenic organisms, including bacteria, viruses, parasites, and

Externí odkaz: https://doaj.org/article/bba35ed07cc441348c3987da0c9147cf

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Akademický článek

The impact of bacterial contamination on the host response towards fully absorbable poly-4-hydroxybutyrate and nonabsorbable polypropylene pelvic floor implants

Autor: Kim W.J. Verhorstert, Martijn Riool, Tess Bulten, Zeliha Guler, Leonie de Boer, Jan-Paul W.R. Roovers, Sebastian A.J. Zaat

Publikováno v: Materials Today Bio, Vol 15, Iss , Pp 100268- (2022)

Polypropylene (PP) implants for the vaginal surgical correction of pelvic organ prolapse (POP) are known for adverse events, like vaginal or visceral exposures. It is hypothesized that this is a result of a prolonged inflammatory response. One of the

Externí odkaz: https://doaj.org/article/ebd8867af3f84e559cd2b153ef45082b

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Akademický článek

Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial

Autor: Maarten J Deenen, Jacobus W A Burger, Cornelis Verhoef, Eva V E Madsen, Koen P Rovers, Alexander Constantinides, Geert-Jan M Creemers, Nadine Leonie de Boer, Alexandra R M Brandt-Kerkhof, Marjolein Diepeveen, Esther van Meerten, Ruben A G van Eerden, Femke M de Man, Rachida Bouamar, Stijn L W Koolen, Ignace H J T de Hingh, Checca Bakkers, Onno W Kranenburg, Ron H J Mathijssen

Publikováno v: BMJ Open, Vol 9, Iss 12 (2019)

Introduction Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has become standard of care for patients with peritoneal metastases of colorectal origin with a low/moderate abdominal disease load. In case of a peritoneal

Externí odkaz: https://doaj.org/article/1ac30eab2d114a75841ee864e7752455

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CalcAMP

Autor: Colin Bournez, Martijn Riool, Leonie de Boer, Robert A. Cordfunke, Leonie de Best, Remko van Leeuwen, Jan Wouter Drijfhout, Sebastian A. J. Zaat, Gerard J. P. van Westen

Publikováno v: Antibiotics; Volume 12; Issue 4; Pages: 725
Antibiotics, 12(4):725
Antibiotics, 12(4):725. Multidisciplinary Digital Publishing Institute (MDPI)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc8bc37eb251bc4d3bda010ce4400bf
https://hdl.handle.net/1887/3618249

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Development of an Antimicrobial Peptide SAAP-148-Functionalized Supramolecular Coating on Titanium to Prevent Biomaterial-Associated Infections

Autor: Moniek G. J. Schmitz, Martijn Riool, Leonie de Boer, Annika F. Vrehen, Paul A. A. Bartels, Sebastian A. J. Zaat, Patricia Y. W. Dankers

Publikováno v: Advanced Materials Technologies. Wiley-Blackwell

Titanium implants are widely used in medicine but have a risk of biomaterial-associated infection (BAI), of which traditional antibiotic-based treatment is affected by resistance. Antimicrobial peptides (AMPs) are used to successfully kill antibiotic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc60db3fcb594df9497edf3c73837f68
https://pure.amc.nl/en/publications/development-of-an-antimicrobial-peptide-saap148functionalized-supramolecular-coating-on-titanium-to-prevent-biomaterialassociated-infections(6f4dfe9f-34c7-41a1-bb8c-fe712adc6f62).html

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Transvaginal Mesh-Related Complications and the Potential Role of Bacterial Colonization: an Exploratory Observational Study

Autor: Chantal M. Diedrich, Kim W.J. Verhorstert, Martijn Riool, Heleen Schuster, Leonie de Boer, Judith Kikhney, Annette Moter, Sebastian A.J. Zaat, Jan-Paul W.R. Roovers

Publikováno v: Journal of minimally invasive gynecology.

The aim of this study was to investigate the potential role of transvaginal mesh bacterial colonization in the development of mesh-related complication (MRCs).An observational and exploratory study was performed including 49 patients indicated for me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0676cf48e9d0ca74f99676f0cb8fd759
https://pubmed.ncbi.nlm.nih.gov/36442754

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Photochemical Internalization as a New Strategy to Enhance Efficacy of Antimicrobial Agents Against Intracellular Infections

Autor: Xiaolin, Zhang, Leonie, de Boer, Sebastian A J, Zaat

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2451

Pathogens such as Staphylococcus aureus are able to survive in many types of host cells including phagocytes such as neutrophils and macrophages, thereby resulting in intracellular infections. Treatment of intracellular infections by conventional ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3125065d202e088d0b6a43deb560e242
https://pubmed.ncbi.nlm.nih.gov/35505040

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IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming

Autor: Alwin J. van der Ham, Gestur Vidarsson, Leonie de Boer, Haneen Harbiye, Sona Allahverdiyeva, Bart Everts, Sebastiaan A. J. Zaat, Steven W. de Taeye, Willianne Hoepel, Riekelt H. Houtkooper, Michel van Weeghel, Dominique Baeten, Jeroen den Dunnen

Publikováno v: The Journal of Immunology
Journal of immunology (Baltimore, Md., 205(12), 3400-3407. American Association of Immunologists
Journal of Immunology, 205(12), 3400-3407. AMER ASSOC IMMUNOLOGISTS

IgG Abs are crucial for various immune functions, including neutralization, phagocytosis, and Ab-dependent cellular cytotoxicity. In this study, we identified another function of IgG by showing that IgG immune complexes elicit distinct cytokine profi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ef4957127a08c5763ba023579c1ef5
https://syndication.highwire.org/content/doi/10.4049/jimmunol.2000263

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Synergistic microbicidal effect of cationic antimicrobial peptides and teicoplanin against planktonic and biofilm-encased Staphylococcus aureus

Autor: Sebastian A. J. Zaat, Leonie de Boer, Jan W. Drijfhout, Martijn Riool, Bruce C. Koppen, Patrick P. G. Mulder

Publikováno v: International Journal of Antimicrobial Agents, 53(2), 143-151
International journal of antimicrobial agents, 53(2), 143-151. Elsevier

Antibiotic resistance and biofilm formation are the main reasons for failure in treatment of bacterial infections. This study aimed to identify synergistic combinations of conventional antibiotics and novel synthetic antimicrobial and antibiofilm pep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f8d01ca67c236435b624e296ebd5b7
https://doi.org/10.1016/j.ijantimicag.2018.10.002

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In Vitro Bacterial Adhesion and Biofilm Formation on Fully Absorbable Poly-4-hydroxybutyrate and Nonabsorbable Polypropylene Pelvic Floor Implants

Autor: Jan-Paul W. R. Roovers, Kim W J Verhorstert, Zeliha Guler, Leonie de Boer, Martijn Riool, Sebastian A. J. Zaat

Publikováno v: ACS Applied Materials & Interfaces
ACS Applied Materials and Interfaces, 12(48), 53646-53653. American Chemical Society
ACS applied materials & interfaces. American Chemical Society

Knitted polypropylene (PP) implants for the correction of pelvic organ prolapse have been associated with complications such as vaginal exposure, infection, and pain. Since certain complications may be linked to bacterial contamination and persistent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3747c35635adb93366b96c6a195c75
https://pubmed.ncbi.nlm.nih.gov/33210919

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