Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Leonie, Helder"'
Autor:
Jorge Domínguez-Andrés, Rob J.W. Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A. Blok, L. Charlotte J. de Bree, Mariolina Bruno, Özlem Bulut, Priya A. Debisarun, Helga Dijkstra, Jéssica Cristina dos Santos, Anaísa V. Ferreira, Daniela Flores-Gomez, Laszlo A. Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A.C.M. Koeken, Heidi Lemmers, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jelmer H. van Puffelen, Katrin Rabold, Rutger J. Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P. Riksen, Leo A.B. Joosten, Mihai G. Netea
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100365- (2021)
Summary: A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline he
Externí odkaz:
https://doaj.org/article/e0ee4ea53a9e4be785098507068f1cd9
Autor:
Samuel T. Keating, Laszlo Groh, Charlotte D.C.C. van der Heijden, Hanah Rodriguez, Jéssica C. dos Santos, Stephanie Fanucchi, Jun Okabe, Harikrishnan Kaipananickal, Jelmer H. van Puffelen, Leonie Helder, Marlies P. Noz, Vasiliki Matzaraki, Yang Li, L. Charlotte J. de Bree, Valerie A.C.M. Koeken, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jorge Domínguez-Andrés, Marije Oosting, Elianne P. Bulthuis, Werner J.H. Koopman, Musa Mhlanga, Assam El-Osta, Leo A.B. Joosten, Mihai G. Netea, Niels P. Riksen
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Trained immunity confers a sustained augmented response of innate immune cells to a secondary challenge, via a process dependent on metabolic and transcriptional reprogramming. Because of its previous associations with metabolic and transcri
Externí odkaz:
https://doaj.org/article/582bb41700f44997a86db25e19d81b8d
Autor:
Kim I, Albers, Fatih, Polat, Leonie, Helder, Ivo F, Panhuizen, Marc M J, Snoeck, S Bas W, Polle, Hilbert, de Vries, Esther M, Dias, Gerrit D, Slooter, Hans D, de Boer, Oscar, Diaz-Cambronero, Guido, Mazzinari, Gert-Jan, Scheffer, Christiaan, Keijzer, Michiel C, Warlé, Sharonne, de Zeeuw
Publikováno v:
Annals of Surgery, 276, 6, pp. e664-e673
Annals of Surgery, 276, e664-e673
Annals of Surgery, 276, e664-e673
Contains fulltext : 286720.pdf (Publisher’s version ) (Open Access) OBJECTIVE: To study the effects of intra-abdominal pressure on the quality of recovery and innate cytokine production capacity after laparoscopic colorectal surgery within the enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778f3c18a94b251a60b20234c3305363
https://doi.org/10.1097/SLA.0000000000005491
https://doi.org/10.1097/SLA.0000000000005491
Autor:
Vera P. Mourits, Valerie A. C. M. Koeken, Els M.A. van de Westerlo, L. Charlotte J. de Bree, Mihai G. Netea, Charlotte D C C van der Heijden, Simone J.C.F.M. Moorlag, Leo A. B. Joosten, Laszlo Groh, Vasiliki Matzaraki, Alexander Hoischen, Werner J.H. Koopman, Anaisa V. Ferreira, Leonie Helder, Samuel T. Keating, Niels P. Riksen, Boris Novakovic, Jelmer H. van Puffelen
Publikováno v:
Immunometabolism
Immunometabolism, 3, 3
Immunometabolism, 3
Immunometabolism, 3, 3
Immunometabolism, 3
Contains fulltext : 237922.pdf (Publisher’s version ) (Open Access) Following brief exposure to endogenous atherogenic particles, such as oxidized low-density lipoprotein (oxLDL), monocytes/macrophages can adopt a long-term pro-inflammatory phenoty
Autor:
Valerie A.C.M. Koeken, Jelmer H. van Puffelen, Samuel T. Keating, Mihai G. Netea, Leonie Helder, Charlotte D C C van der Heijden, L. Charlotte J. de Bree, Martin Jaeger, Simone J.C.F.M. Moorlag, Vera P. Mourits, Vasiliki Matzaraki, Leo A. B. Joosten, Laszlo Groh
Publikováno v:
Mourits, V P, Helder, L S, Matzaraki, V, Koeken, V A C M, Groh, L, de Bree, L C J, Moorlag, S J C F M, van der Heijden, C D C C, Keating, S T, van Puffelen, J H, Jaeger, M, Joosten, L A B & Netea, M G 2021, ' The role of sirtuin 1 on the induction of trained immunity ', Cellular Immunology, vol. 366, 104393 . https://doi.org/10.1016/j.cellimm.2021.104393
Cellular Immunology, 366
Cell Immunol.
Cellular immunology, 366:104393, 1-8. ACADEMIC PRESS INC ELSEVIER SCIENCE
Cellular immunology
Netherlands
Cellular Immunology, 366
Cell Immunol.
Cellular immunology, 366:104393, 1-8. ACADEMIC PRESS INC ELSEVIER SCIENCE
Cellular immunology
Netherlands
Sirtuin 1 (SIRT1) has been described to modify immune responses by modulation of gene transcription. As transcriptional reprogramming is the molecular substrate of trained immunity, a de facto innate immune memory, we investigated the role of SIRT1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abad39055d9b76642ac0d496c1b9e947
https://curis.ku.dk/ws/files/274115940/The_role_of_sirtuin_1_on_the_induction_of_trained_immunity.pdf
https://curis.ku.dk/ws/files/274115940/The_role_of_sirtuin_1_on_the_induction_of_trained_immunity.pdf
Autor:
Katrin Rabold, Liesbeth Jacobs, Jéssica Cristina dos Santos, Leo A. B. Joosten, Heidi Lemmers, Laszlo Groh, Viola Klück, Harsh Bahrar, Inge Grondman, Trees Jansen, Gizem Kilic, Priya A. Debisarun, Reinout van Crevel, Vera P. Mourits, Rutger J. Röring, Leonie Helder, Jelmer H. van Puffelen, Diletta Rosati, Jorge Domínguez-Andrés, Niels P. Riksen, Anaisa V. Ferreira, Bastiaan A. Blok, L. Charlotte J. de Bree, Mihai G. Netea, Valerie A. C. M. Koeken, Cor Jacobs, Rob J.W. Arts, Helga Dijkstra, Daniela Flores-Gomez, Julia van Tuijl, Jessica Quintin, Simone J.C.F.M. Moorlag, Helin Tercan, Mariolina Bruno, Ozlem Bulut, Siroon Bekkering
Publikováno v:
STAR Protocols
STAR Protocols, 2
STAR Protocols, Vol 2, Iss 1, Pp 100365-(2021)
STAR Protocols, 2, 1
STAR Protocols, 2
STAR Protocols, Vol 2, Iss 1, Pp 100365-(2021)
STAR Protocols, 2, 1
Summary A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b20cf0ee143c59f9170a1a6f3ff814
https://doi.org/10.1016/j.xpro.2021.100365
https://doi.org/10.1016/j.xpro.2021.100365
Autor:
Leonie Helder, Stan Buckens, Nicol C. Voermans, Ignacio Malagon, Nens van Alfen, Gert Jan Scheffer, Anna Greco, M.M.J. Snoeck, Baziel G.M. van Engelen, José A. E. Custers, Lucas T. van Eijk, Sheila Riazi, Luuk R van den Bersselaar, Nick Kruijt, Heinz Jungbluth, Susan Treves, Leo A. B. Joosten
Publikováno v:
Medicine (Baltimore), 100, 33
Medicine (Baltimore), 100
Medicine
Medicine (Baltimore), 100
Medicine
Contains fulltext : 238097.pdf (Publisher’s version ) (Open Access) INTRODUCTION: Malignant hyperthermia (MH) and exertional rhabdomyolysis (ERM) have long been considered episodic phenotypes occurring in response to external triggers in otherwise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d863f4d0358e938c0e6125b1216cfee1
https://doi.org/10.1097/MD.0000000000026999
https://doi.org/10.1097/MD.0000000000026999
Autor:
Harikrishnan Kaipananickal, Simone J.C.F.M. Moorlag, Hanah Rodriguez, Niels P. Riksen, Werner J.H. Koopman, Leonie Helder, Assam El-Osta, L. Charlotte J. de Bree, Jelmer H. van Puffelen, Elianne P. Bulthuis, Yang Li, Musa M. Mhlanga, Jun Okabe, Mihai G. Netea, Vasiliki Matzaraki, Marlies P. Noz, Marije Oosting, Valerie A. C. M. Koeken, Jorge Domínguez-Andrés, Stephanie Fanucchi, Samuel T. Keating, Vera P. Mourits, Charlotte D C C van der Heijden, Laszlo Groh, Jéssica Cristina dos Santos, Leo A. B. Joosten
Publikováno v:
Keating, S T, Groh, L, van der Heijden, C D C C, Rodriguez, H, dos Santos, J C, Fanucchi, S, Okabe, J, Kaipananickal, H, van Puffelen, J H, Helder, L, Noz, M P, Matzaraki, V, Li, Y, de Bree, L C J, Koeken, V A C M, Moorlag, S J C F M, Mourits, V P, Domínguez-Andrés, J, Oosting, M, Bulthuis, E P, Koopman, W J H, Mhlanga, M, El-Osta, A, Joosten, L A B, Netea, M G & Riksen, N P 2020, ' The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan ', Cell Reports, vol. 31, no. 3, 107548 . https://doi.org/10.1016/j.celrep.2020.107548
Cell Reports, 31, 3
Cell Reports
Cell Reports, 31
Cell reports
United States
Cell Reports, Vol 31, Iss 3, Pp-(2020)
Cell Reports, 31, 3
Cell Reports
Cell Reports, 31
Cell reports
United States
Cell Reports, Vol 31, Iss 3, Pp-(2020)
Summary Trained immunity confers a sustained augmented response of innate immune cells to a secondary challenge, via a process dependent on metabolic and transcriptional reprogramming. Because of its previous associations with metabolic and transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9257583e50f9a6e25fc9758839126128
https://findresearcher.sdu.dk:8443/ws/files/169382641/PIIS2211124720304587.pdf
https://findresearcher.sdu.dk:8443/ws/files/169382641/PIIS2211124720304587.pdf
Publikováno v:
International Journal of Pharmaceutics, 564, 1-9
International Journal of Pharmaceutics, 564, pp. 1-9
International Journal of Pharmaceutics, 564, pp. 1-9
The aim of this study was to investigate the influence of end group of poly(lactic-co-glycolic acid) (PLGA) on the drug loading and release behavior of electrospray-generated PLGA microspheres. To this end, doxycycline hyclate (DOX) was selected as a
Autor:
Vasiliki Matzaraki, Musa M. Mhlanga, Laszlo Groh, Valerie A. C. M. Koeken, Jelmer H. van Puffelen, Samuel T. Keating, Simone J.C.F.M. Moorlag, Mihai G. Netea, Jun Okabe, Harikrishnan Kn, Leonie Helder, Marlies P. Noz, Niels P. Riksen, Stephanie Fanucchi, Jorge Domínguez-Andrés, Charlotte D C C van der Heijden, Jéssica Cristina dos Santos, Leo A. B. Joosten, Vera P. Mourits, Yang Li, Marije Oosting, Assam El-Osta, Charlotte de Bree, Hanah Rodriguez
Publikováno v:
SSRN Electronic Journal.
Trained immunity confers a sustained augmented response of innate immune cells to a secondary challenge, via a process dependent on metabolic and epigenetic reprogramming. Because of its previous associations to metabolic and epigenetic memory, as we