Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Leonidas, Salichos"'
Autor:
Manrose Singh, Samantha Cornwell, Ariel Shaddaie, Leah Wachsmuth, Ashwin Ragupathi, Leonidas Salichos, Sandra Nissel-Horowitz, Rajasree Roy, Maria Plummer, Dong Zhang, Bhoomi Mehrotra
Publikováno v:
Gynecologic Oncology Reports, Vol 54, Iss , Pp 101417- (2024)
We describe a patient diagnosed with a metastatic adenocarcinoma of Müllerian origin, harboring a BRAF V600E mutation, ten years after being treated for a serous borderline tumor (SBOT). While BRAF mutations in the setting of SBOTs are common, they
Externí odkaz:
https://doaj.org/article/929721362e6440d383dbd360b99865fa
Autor:
David L Rimm, Kurt A Schalper, Myrto K Moutafi, Ioannis A Vathiotis, Niki Gavrielatou, Katherine M Bates, Thazin Nwe Aung, Rolando Garcia Milian, Vasiliki Xirou, Athanasios Angelakis, Leonidas Salichos
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background Despite the impressive outcomes with immune checkpoint inhibitor (ICI) in non-small cell lung cancer (NSCLC), only a minority of the patients show long-term benefits from ICI. In this study, we used retrospective cohorts of ICI treated pat
Externí odkaz:
https://doaj.org/article/5c7458e2e485439097b4e6dbfd5e0655
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract For the COVID-19 pandemic, viral transmission has been documented in many historical and geographical contexts. Nevertheless, few studies have explicitly modeled the spatiotemporal flow based on genetic sequences, to develop mitigation strat
Externí odkaz:
https://doaj.org/article/0a68916765484e4a875126b56157bd78
Publikováno v:
Journal of Orthopaedic Translation, Vol 39, Iss , Pp 113-123 (2023)
Background: Nonunions remain a challenging post-traumatic complication that often leads to a financial and health burden that affects the patient's quality of life. Despite a wealth of knowledge about fracture repair, especially gene and more recentl
Externí odkaz:
https://doaj.org/article/60b6e37776964d9da6b52895f2a214a2
Autor:
Ioannis A. Vathiotis, Leonidas Salichos, Sandra Martinez-Morilla, Niki Gavrielatou, Thazin Nwe Aung, Saba Shafi, Pok Fai Wong, Shlomit Jessel, Harriet M. Kluger, Konstantinos N. Syrigos, Sarah Warren, Mark Gerstein, David L. Rimm
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-8 (2022)
Abstract Treatment with immune checkpoint inhibitors has altered the course of malignant melanoma, with approximately half of the patients with advanced disease surviving for more than 5 years after diagnosis. Currently, there are no biomarker method
Externí odkaz:
https://doaj.org/article/956f4e8b0c1545fa97bfbb01c858e7bd
Autor:
Leonidas Salichos, Claudia Minosse, Ubaldo Visco-Comandini, Chiara Taibi, Verdiana Zulian, Gianpiero D’Offizi, Nayan Pallothu, Fiona McPhee, Anna Rosa Garbuglia
Publikováno v:
Viruses, Vol 15, Iss 9, p 1791 (2023)
The hepatitis delta virus (HDV) exhibits high genetic and evolutionary variability and is classified into eight genotypes (HDV-1 to -8). HDV-1 is the most widespread genotype worldwide and includes several subtypes. It predominates mainly in Europe,
Externí odkaz:
https://doaj.org/article/15e48ac3494945f1871df374407ef3d0
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
There are many methods to detect cancer-driving mutations. Here, the authors harness the variant allele frequency of mutations in tumor cells of a single individual to present a method that can estimate growth patterns and identify driver gene evolut
Externí odkaz:
https://doaj.org/article/6c6a5bf56eac4983a05e8f4f824a7d1c
Autor:
Catia Sias, Leonidas Salichos, Daniele Lapa, Franca Del Nonno, Andrea Baiocchini, Maria Rosaria Capobianchi, Anna Rosa Garbuglia
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-10 (2019)
Abstract Background Recent studies have shown a 13-fold increase of oropharyngeal cancer in the presence of HPV, while α-HPV detection seems to be rare in oral cavity in comparison to anal or cervical district, many novel β and γ types have been i
Externí odkaz:
https://doaj.org/article/ef987e6aeb2b404fab9be0b820c37db2
Autor:
Claudia Minosse, Leonidas Salichos, Chiara Taibi, Ilaria Luzzitelli, Daniela Nardozi, Maria Rosaria Capobianchi, Gianpiero D’Offizi, Fiona McPhee, Anna Rosa Garbuglia
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1432 (2021)
Approximately 71 million people worldwide are infected with the hepatitis C virus (HCV). Injectable drug use represents the most common route of transmission in Europe and other developed countries. We studied the molecular characteristics of the HCV
Externí odkaz:
https://doaj.org/article/b5954dd15523429aa9ee7346f697e9e1
Autor:
Guangda Shi, Claire Song, Jaylissa Torres Robles, Leonidas Salichos, Hua Jane Lou, TuKiet T. Lam, Mark Gerstein, Benjamin E. Turk
Publikováno v:
Science Signaling. 16
Essential functions of mitogen-activated protein kinases (MAPKs) depend on their capacity to selectively phosphorylate a limited repertoire of substrates. MAPKs harbor a conserved groove located outside of the catalytic cleft that binds to short line