Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Leonid V Zingman"'
Autor:
Francoise A Gourronc, Kathleen R Markan, Katarina Kulhankova, Zhiyong Zhu, Ryan Sheehy, Dawn E Quelle, Leonid V Zingman, Zoya B Kurago, James A Ankrum, Aloysius J Klingelhutz
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236741 (2020)
Aryl hydrocarbon receptor (AHR) agonists such as dioxin have been associated with obesity and the development of diabetes. Whole-body Ahr knockout mice on high-fat diet (HFD) have been shown to resist obesity and hepatic steatosis. Tissue-specific kn
Externí odkaz:
https://doaj.org/article/27c70c7efd0c42fbbb3d8d2fe307dec7
Autor:
Arpit Sharma, Lalita Oonthonpan, Ryan D Sheldon, Adam J Rauckhorst, Zhiyong Zhu, Sean C Tompkins, Kevin Cho, Wojciech J Grzesik, Lawrence R Gray, Diego A Scerbo, Alvin D Pewa, Emily M Cushing, Michael C Dyle, James E Cox, Chris Adams, Brandon S Davies, Richard K Shields, Andrew W Norris, Gary Patti, Leonid V Zingman, Eric B Taylor
Publikováno v:
eLife, Vol 8 (2019)
Metabolic cycles are a fundamental element of cellular and organismal function. Among the most critical in higher organisms is the Cori Cycle, the systemic cycling between lactate and glucose. Here, skeletal muscle-specific Mitochondrial Pyruvate Car
Externí odkaz:
https://doaj.org/article/13cd1adfdce945bdbb60969f1404d117
Autor:
Zhan Gao, Ana Sierra, Zhiyong Zhu, Siva Rama Krishna Koganti, Ekaterina Subbotina, Ankit Maheshwari, Mark E Anderson, Leonid V Zingman, Denice M Hodgson-Zingman
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151337 (2016)
The search for new approaches to treatment and prevention of heart failure is a major challenge in medicine. The adenosine triphosphate-sensitive potassium (KATP) channel has been long associated with the ability to preserve myocardial function and v
Externí odkaz:
https://doaj.org/article/040aa5ba7c4846d1868cfc7190200a87
Autor:
Matthew P. Harris, Shemin Zeng, Zhiyong Zhu, Vitor A. Lira, Liping Yu, Denice M. Hodgson-Zingman, Leonid V. Zingman
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6525 (2023)
This study investigates the role and mechanisms by which the myokine musclin promotes exercise-induced cardiac conditioning. Exercise is one of the most powerful triggers of cardiac conditioning with proven benefits for healthy and diseased hearts. T
Externí odkaz:
https://doaj.org/article/0f3f177315eb46f697f8fd6b87451851
Autor:
Kristin E. Claflin, Andrew I. Sullivan, Meghan C. Naber, Kyle H. Flippo, Donald A. Morgan, Tate J. Neff, Sharon O. Jensen-Cody, Zhiyong Zhu, Leonid V. Zingman, Kamal Rahmouni, Matthew J. Potthoff
Publikováno v:
Molecular metabolism. 64
Fibroblast growth factor 21 (FGF21) is a peripherally-derived endocrine hormone that acts on the central nervous system (CNS) to regulate whole body energy homeostasis. Pharmacological administration of FGF21 promotes weight loss in obese animal mode
Autor:
Zhiyong Zhu, Jingwei Jiang, Yue Deng, Kenji Saito, Huxing Cui, Guorui Deng, Joel C. Geerling, Uday Singh, Baojian Xue, Jacob E. Dickey, Leonid V. Zingman, Brandon A. Toth, Samuel R. Rodeghiero
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 55, Iss, Pp 101401-(2022)
Molecular Metabolism, Vol 55, Iss, Pp 101401-(2022)
Objective The paraventricular nucleus of hypothalamus (PVN), an integrative center in the brain, orchestrates a wide range of physiological and behavioral responses. While the PVN melanocortin 4 receptor (MC4R) signaling (PVNMC4R+) is involved in fee
Autor:
Yue Deng, Jacob E. Dickey, Kenji Saito, Guorui Deng, Uday Singh, Jingwei Jiang, Brandon A. Toth, Zhiyong Zhu, Leonid V. Zingman, Jon M. Resch, Justin L. Grobe, Huxing Cui
Publikováno v:
Molecular Metabolism. 66:101622
RGS2 is a GTPase activating protein that modulates GPCR-GWe used a combination of RNAscope in situ hybridization (ISH), immunohistochemistry, and bioinformatic analyses to characterize the pattern of Rgs2 expression in the PVN. We then created mice l
Autor:
Kamal Rahmouni, Zhiyong Zhu, Leonid V. Zingman, Mohamed Rouabhi, Deng-Fu Guo, Justin L. Grobe, Donald A. Morgan, Miguel López
Publikováno v:
Molecular Metabolism, Vol 48, Iss, Pp 101211-(2021)
Molecular Metabolism
Molecular Metabolism
Objectives The hypothalamic ventromedial nucleus (VMH) plays a major role in metabolic control, but the molecular mechanisms involved remain poorly defined. We analyzed the relevance of the BBSome, a protein complex composed of 8 Bardet–Biedl syndr
Autor:
Chad E. Grueter, Leonid V Zingman, Isabella M. Grumbach, Kaikobad Irani, Olha M. Koval, Xiaoyi Zhu, Ekaterina Subbotina, Ana Sierra, Duane D. Hall, Young-Rae Kim, Zhan Gao, Denice M. Hodgson-Zingman, Jun Yang, Long-Sheng Song, Biyi Chen, Zhiyong Zhu, Rachel A Minerath
Publikováno v:
Europace
Aims The study investigates the role and mechanisms of clinically translatable exercise heart rate (HR) envelope effects, without dyssynchrony, on myocardial ischaemia tolerance compared to standard preconditioning methods. Since the magnitude and du
Autor:
Huxing Cui, Uday Singh, Zhiyong Zhu, Leonid V. Zingman, Kenji Saito, Baojian Xue, Brandon A. Toth, Jacob E. Dickey
Publikováno v:
The FASEB Journal. 35