Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Leonid Olender"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Adult hematopoietic stem cells (HSCs) in the bone marrow (BM) are quiescent. Following perturbations, such as blood loss or infection, HSCs may undergo activation. Surprisingly, little is known about the earliest stages of HSCs activation. W
Externí odkaz:
https://doaj.org/article/6245967585cc4582854220be55eea2b7
Autor:
Omri Sharabi, Yariv Greenshpan, Noa Ofir, Aner Ottolenghi, Tamar Levi, Leonid Olender, Zachor Adler-Agmon, Angel Porgador, Roi Gazit
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cancer immunotherapies are highly potent and are gaining wide clinical usage. However, severe side effects require focusing effector immune cell activities on the tumor microenvironment (TME). We recently developed a chimeric antigen recepto
Externí odkaz:
https://doaj.org/article/a8c3491aaadb47f198961624d9339fd6
Publikováno v:
Cells, Vol 11, Iss 3, p 350 (2022)
Myeloid progenitors are intermediates between Hematopoietic Stem Cells (HSCs) and Myeloid effector progeny. In mouse bone marrow, they are part of the Lineage− cKit+ Sca1− (LK) compartment. To date, most researchers used CD34 and FcγR surface ma
Externí odkaz:
https://doaj.org/article/7b5e4c7ff15e49dea48f52a5f6e3d02d
Autor:
Shahar Biechonski, Leonid Olender, Adi Zipin-Roitman, Muhammad Yassin, Nasma Aqaqe, Victoria Marcu-Malina, Melanie Rall-Scharpf, Magan Trottier, M. Stephen Meyn, Lisa Wiesmüller, Katia Beider, Yael Raz, Dan Grisaru, Arnon Nagler, Michael Milyavsky
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Failure to precisely repair DNA damage in self-renewing Hematopoietic Stem and early Progenitor Cells (HSPCs) can disrupt normal hematopoiesis and promote leukemogenesis. Although HSPCs are widely considered a target of ionizing radiation (I
Externí odkaz:
https://doaj.org/article/9313fac1c8ce4adb8917c5a6468462c9
Autor:
Omri Sharabi, Yariv Greenshpan, Noa Ofir, Aner Ottolenghi, Tamar Levi, Leonid Olender, Zachor Adler-Agmon, Angel Porgador, Roi Gazit
Publikováno v:
Scientific reports. 12(1)
Cancer immunotherapies are highly potent and are gaining wide clinical usage. However, severe side effects require focusing effector immune cell activities on the tumor microenvironment (TME). We recently developed a chimeric antigen receptor tumor-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c300ad1dff0b7b5f8b1242a529390463
https://pubmed.ncbi.nlm.nih.gov/35504918
https://pubmed.ncbi.nlm.nih.gov/35504918
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2185
Reprogramming proved the possibility to change cell identity by transient overexpression of defined transcription factors. However, the efficiencies of pioneer protocols are extremely low, and mechanistic understanding is still under intensive resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f928b9ba4f46613ae97cb5070dfa6669
https://pubmed.ncbi.nlm.nih.gov/33165863
https://pubmed.ncbi.nlm.nih.gov/33165863
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Haematopoietic stem cells (HSCs) have the potential for lifetime production of blood and immune cells. The introduction of transgenes into HSCs is important for basic research, as well as for multiple clinical applications, because HSC transplantatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758845229e73ab56180833d44eaf6bf9
http://europepmc.org/articles/PMC7000727
http://europepmc.org/articles/PMC7000727
Publikováno v:
Cells, Vol 11, Iss 350, p 350 (2022)
Myeloid progenitors are intermediates between Hematopoietic Stem Cells (HSCs) and Myeloid effector progeny. In mouse bone marrow, they are part of the Lineage− cKit+ Sca1− (LK) compartment. To date, most researchers used CD34 and FcγR surface ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4572d76e409a2ce39d1146fdcc0b20
https://doi.org/10.2139/ssrn.3680823
https://doi.org/10.2139/ssrn.3680823
Publikováno v:
Experimental Hematology. 100:S96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6e38ef2b152fb6e5f821635a966bc0
https://doi.org/10.1016/j.exphem.2021.12.328
https://doi.org/10.1016/j.exphem.2021.12.328
Publikováno v:
Experimental Hematology. 100:S94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e07efdf91a5867511eb72bb1408dd33b
https://doi.org/10.1016/j.exphem.2021.12.324
https://doi.org/10.1016/j.exphem.2021.12.324