Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leonid O. Bryzgalov"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7955 (2023)
Alzheimer’s disease (AD) is a prevalent type of dementia in elderly populations with a significant genetic component. The accumulating evidence suggests that AD involves a reconfiguration of the epigenetic landscape, including DNA methylation, post
Externí odkaz:
https://doaj.org/article/5663097fa7544fbe983474d60779c247
Autor:
Leonid O. Bryzgalov, Elena E. Korbolina, Ilja I. Brusentsov, Elena Y. Leberfarb, Natalia P. Bondar, Tatiana I. Merkulova
Publikováno v:
BMC Neuroscience, Vol 19, Iss S1, Pp 41-56 (2018)
Abstract Background A challenge of understanding the mechanisms underlying cognition including neurodevelopmental and neuropsychiatric disorders is mainly given by the potential severity of cognitive disorders for the quality of life and their preval
Externí odkaz:
https://doaj.org/article/12cbdc1364a0445baf9ef0731b24a273
Autor:
Elena E. Korbolina, Leonid O. Bryzgalov, Diana Z. Ustrokhanova, Sergey N. Postovalov, Dmitry V. Poverin, Igor S. Damarov, Tatiana I. Merkulova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7240 (2021)
Currently, the detection of the allele asymmetry of gene expression from RNA-seq data or the transcription factor binding from ChIP-seq data is one of the approaches used to identify the functional genetic variants that can affect gene expression (re
Externí odkaz:
https://doaj.org/article/4b91b831ba2346eb91e713df9173df65
Publikováno v:
BMC Genomics
Background Etiology of complex disorders, such as cataract and neurodegenerative diseases including age-related macular degeneration (AMD), remains poorly understood due to the paucity of animal models, fully replicating the human disease. Previously
Autor:
Tatyana I. Merkulova, Konstantin Y. Kropachev, Olga A. Timofeeva, Gennady V. Vasiliev, Zoia B. Levashova, Svetlana I. Ilnitskaya, Victor F. Kobzev, Maria Yu Pakharukova, Leonid O. Bryzgalov, Vasily I. Kaledin
Publikováno v:
Molecular Carcinogenesis; Dec2005, Vol. 44 Issue 4, p223-232, 0p
Autor:
Leonid O Bryzgalov, Elena V Antontseva, Marina Yu Matveeva, Alexander G Shilov, Elena V Kashina, Viatcheslav A Mordvinov, Tatyana I Merkulova
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78833 (2013)
A vast amount of SNPs derived from genome-wide association studies are represented by non-coding ones, therefore exacerbating the need for effective identification of regulatory SNPs (rSNPs) among them. However, this task remains challenging since th
Externí odkaz:
https://doaj.org/article/eddd49633c714772a212d624cf6ca4cd