Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Leonid N, Maslov"'
The Nephroprotective Effect of Nitric Oxide during Extracorporeal Circulation: An Experimental Study
Autor:
Nikolay O. Kamenshchikov, Yuri K. Podoksenov, Boris N. Kozlov, Leonid N. Maslov, Alexander V. Mukhomedzyanov, Mark A. Tyo, Alexander M. Boiko, Natalya Yu. Margolis, Alla A. Boshchenko, Olga N. Serebryakova, Anna N. Dzyuman, Alexander S. Shirshin, Sergey N. Buranov, Victor D. Selemir
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1298 (2024)
This study aims to determine the effectiveness of administering 80 ppm nitric oxide in reducing kidney injury, mitochondrial dysfunction and regulated cell death in kidneys during experimental perfusion. Twenty-four sheep were randomized into four gr
Externí odkaz:
https://doaj.org/article/a22e7b68d6ef4c5e838e889353299ab8
Potential Mechanisms for Organoprotective Effects of Exogenous Nitric Oxide in an Experimental Study
Autor:
Nikolay O. Kamenshchikov, Mariia L. Diakova, Yuri K. Podoksenov, Elena A. Churilina, Tatiana Yu. Rebrova, Shamil D. Akhmedov, Leonid N. Maslov, Alexander V. Mukhomedzyanov, Elena B. Kim, Ekaterina S. Tokareva, Igor V. Kravchenko, Alexander M. Boiko, Maxim S. Kozulin, Boris N. Kozlov
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 719 (2024)
Performing cardiac surgery under cardiopulmonary bypass (CPB) and circulatory arrest (CA) provokes the development of complications caused by tissue metabolism, microcirculatory disorders, and endogenous nitric oxide (NO) deficiency. This study aimed
Externí odkaz:
https://doaj.org/article/478e34cf93d04d2592207f0a678ef6ec
Autor:
Vyacheslav V. Ryabov, Evgenii V. Vyshlov, Leonid N. Maslov, Natalia V. Naryzhnaya, Alexandr V. Mukhomedzyanov, Alla A. Boshchenko, Ivan A. Derkachev, Boris K. Kurbatov, Andrey V. Krylatov, Aleksandra E. Gombozhapova, Stanislav V. Dil, Julia O. Samoylova, Feng Fu, Jian-Ming Pei, Galina Z. Sufianova, Emiliano R. Diez
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 25, Iss 3, p 105 (2024)
Microvascular obstruction (MVO) of coronary arteries promotes an increase in mortality and major adverse cardiac events in patients with acute myocardial infarction (AMI) and percutaneous coronary intervention (PCI). Intramyocardial hemorrhage (IMH)
Externí odkaz:
https://doaj.org/article/db3fb9131388424da1d18df03daaf628
Autor:
Natalia V. Naryzhnaya, Alexander V. Mukhomedzyanov, Maria Sirotina, Leonid N. Maslov, Boris K. Kurbatov, Alexander S. Gorbunov, Mikhail Kilin, Artur Kan, Andrey V. Krylatov, Yuri K. Podoksenov, Sergey V. Logvinov
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1887 (2023)
An analysis of published data and the results of our own studies reveal that the activation of a peripheral δ2-opioid receptor (δ2-OR) increases the cardiac tolerance to reperfusion. It has been found that this δ2-OR is localized in cardiomyocytes
Externí odkaz:
https://doaj.org/article/c51f5280425a48089168dd68accb7f27
Autor:
Vyacheslav V. Ryabov, Evgenii V. Vyshlov, Leonid N. Maslov, Alexandr V. Mukhomedzyanov, Natalia V. Naryzhnaya, Alla A. Boshchenko, Aleksandra E. Gombozhapova, Julia O. Samoylova
Publikováno v:
Cells, Vol 12, Iss 12, p 1622 (2023)
Acute myocardial infarction (AMI) remains the leading cause of mortality in the world, highlighting an urgent need for the development of novel, more effective approaches for the treatment of AMI. Remote postconditioning (RPost) of the heart could be
Externí odkaz:
https://doaj.org/article/8398c334c47343e8ba5cf128d649c768
Autor:
Sergey V. Popov, Leonid N. Maslov, Alexandr V. Mukhomedzyanov, Boris K. Kurbatov, Alexandr S. Gorbunov, Michail Kilin, Viacheslav N. Azev, Maria S. Khlestkina, Galina Z. Sufianova
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 1029 (2023)
In-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is 5–6%. Consequently, it is necessary to develop fundamentally novel drugs capable of reducing mortality in patients with acute myocardial infarction. Apelin
Externí odkaz:
https://doaj.org/article/fe7a4132eef84e509916bfdaca8da7fc
The Infarct-Reducing Effect of the δ2 Opioid Receptor Agonist Deltorphin II: The Molecular Mechanism
Autor:
Sergey V. Popov, Alexandr V. Mukhomedzyanov, Leonid N. Maslov, Natalia V. Naryzhnaya, Boris K. Kurbatov, N. Rajendra Prasad, Nirmal Singh, Feng Fu, Viacheslav N. Azev
Publikováno v:
Membranes, Vol 13, Iss 1, p 63 (2023)
The search for novel drugs for the treatment of acute myocardial infarction and reperfusion injury of the heart is an urgent aim of modern pharmacology. Opioid peptides could be such potential drugs in this area. However, the molecular mechanism of t
Externí odkaz:
https://doaj.org/article/ad855bce1202445da3663cc66dc9577a
Autor:
Chaoyang Liu, Yuehu Han, Xiaoming Gu, Man Li, Yanyan Du, Na Feng, Juan Li, Shumiao Zhang, Leonid N. Maslov, Guoen Wang, Jianming Pei, Feng Fu, Mingge Ding
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102098- (2021)
Diabetes disrupts mitochondrial function and often results in diabetic cardiomyopathy (DCM). Paeonol is a bioactive compound that has been reported to have pharmacological potential for cardiac and mitochondrial protection. This study aims to explore
Externí odkaz:
https://doaj.org/article/8b0c86eabb9a4c9ca7f586afc906ac27
Autor:
Akylbek Sydykov, Aleksandar Petrovic, Abdirashit M. Maripov, Marija Gredic, Daniel Gerd Bermes, Nadira Kushubakova, Kubatbek Muratali Uulu, Christina Pilz, Meerim Cholponbaeva, Melis Duishobaev, Samatbek Satybaldyev, Nurgul Satieva, Argen Mamazhakypov, Meerim Sartmyrzaeva, Nazgul Omurzakova, Zhainagul Kerimbekova, Nursultan Baktybek, Cholpon Kulchoroeva, Oleg Pak, Lan Zhao, Norbert Weissmann, Sergey Avdeev, Leonid N. Maslov, Hossein Ardeschir Ghofrani, Ralph Theo Schermuly, Akpay S. Sarybaev, Djuro Kosanovic
Publikováno v:
Cells, Vol 11, Iss 19, p 2932 (2022)
The role of microparticles (MPs) and cold in high altitude pulmonary hypertension (HAPH) remains unexplored. We investigated the impact of long-term cold exposure on the pulmonary circulation in lowlanders and high-altitude natives and the role of MP
Externí odkaz:
https://doaj.org/article/418dbde282b0467f9723fd757d025965
Autor:
Leonid N. Maslov, Natalia V. Naryzhnaya, Alla A. Boshchenko, Sergey V. Popov, Vladimir V. Ivanov, Peter R. Oeltgen
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 15, Iss , Pp 1-5 (2019)
Metabolic syndrome is accompanied by oxidative stress in animals and humans. The main source of ROS in experimental metabolic syndrome is NADPH oxidase and possibly adipocyte mitochondria. It is now documented that oxidative stress induces insulin re
Externí odkaz:
https://doaj.org/article/09ff79d83f01477f9c70ff5f121ac76c