Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Leonid Heifets"'
Autor:
Leonid Heifets, Max Salfinger, Jenny Jo Graham, Cathy A. Petti, June I. Pounder, Douglas R. Storts, Karl V. Voelkerding, Jillian Dormandy, Akos Somoskovi, Clint M. Anderson
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 67:101-105
Differentiation of Mycobacterium tuberculosis complex (MTC) species is important for patient management. We developed a genomic deletion assay based on multiplex polymerase chain reaction with melting temperature analysis that correctly identified 12
Autor:
Cecile S. Rose, John W. Martyny, Tracy Sanchez, James Murphy, Lee S. Newman, Leonid Heifets, Craig S. Glazer, Ben Lee, Tricia M. Sells
Publikováno v:
Journal of Occupational and Environmental Hygiene. 4:831-840
Hot tub exposure has been causally associated with a steroid-responsive, granulomatous lung disease featuring nontuberculous mycobacterial (NTM) growth in both clinical and environmental samples. Little is known regarding prevalence of and risk facto
Publikováno v:
Journal of Infection. 54:e227-e231
Mycobacterium neoaurum infection has rarely been found in humans, and only a limited number of cases have been reported. We describe the first case of pulmonary infection with M. neoaurum. We speculate that unrecognized aspiration and long-term corti
Autor:
Charles J. Thompson, Rowan P. Morris, Yang Liu, Jean Pieters, Kevin C. Visconti, John Gatfield, Dirk Schnappinger, Liem Nguyen, Gary K. Schoolnik, Leonid Heifets, Kien T. Nguyen, Sabine Ehrt
Publikováno v:
Proceedings of the National Academy of Sciences. 102:12200-12205
Chemotherapeutic options to treat tuberculosis are severely restricted by the intrinsic resistance of Mycobacterium tuberculosis to the majority of clinically applied antibiotics. Such resistance is partially provided by the low permeability of their
Autor:
Edward Desmond, Leonid Heifets
Publikováno v:
Tuberculosis and the Tubercle Bacillus. :47-69
This chapter presents a broad picture of activities in a diagnostic mycobacteriology laboratory with a focus on Mycobacterium tuberculosis detection, identification, and drug susceptibility testing. Development of rapid methods for mycobacterial spec
Autor:
Leonid Heifets
Publikováno v:
Seminars in Respiratory and Critical Care Medicine. 25:283-295
The purpose of this review is to familiarize a broad range of medical professionals with a relatively new and growing problem of infections caused by mycobacteria other than M. tuberculosis and M. leprae. There are at least 60 mycobacterial species t
Autor:
Manzour Hernando Hazbón, Catherine Vilchèze, Leonid Heifets, James C. Sacchettini, Max Salfinger, Laurent Kremer, David Alland, Gurdyal S. Besra, Michelle H. Larsen, William R. Jacobs, Linda M. Parsons
Publikováno v:
Molecular Microbiology. 46:453-466
The inhA and kasA genes of Mycobacterium tuberculosis have each been proposed to encode the primary target of the antibiotic isoniazid (INH). Previous studies investigating whether overexpressed inhA or kasA could confer resistance to INH yielded dis
Publikováno v:
Infection and Immunity. 70:4591-4599
The ability of human neutrophils to aid in defense against pulmonary infection withMycobacterium tuberculosisis controversial. In this study, we have shown that neutrophils respond to and phagocytoseM. tuberculosisin human lesions. Neutrophils from h
Autor:
Leonid Heifets, Jeffrey R. Starke
Publikováno v:
Seminars in Respiratory and Critical Care Medicine. 18:509-522
Autor:
A Meier, Yansheng Zhang, Richard J. Wallace, Barbara A. Brown, Leonid Heifets, Peter Sander, Erik C. Böttger
Publikováno v:
Journal of Infectious Diseases. 174:354-360
The peptidyltransferase region of the 23S rRNA gene (the probable target site for the macrolides) was investigated in blood isolates of Mycobacterium avium recovered from 38 patients before and after the development of clarithromycin resistance. Poin