Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leonid Gubar"'
Autor:
Cord Sunderkötter, Roland Wedlich-Söldner, Juergen Brosius, Hermann Pavenstädt, Yuri B. Schwartz, Thomas Pap, Boris V. Skryabin, Sven G. Meuth, Helena Kaiser, Anja Stegemann, Johannes Roth, J. Sherwood, Delf-Magnus Kummerfeld, Timofey S. Rozhdestvensky, Birte Seeger, Leonid Gubar
Publikováno v:
Science Advances
Knock-in genome targeting risks: Comprehensive locus analysis is essential for precision chromosome-editing identification.
CRISPR-Cas9–mediated homology-directed DNA repair is the method of choice for precise gene editing in a wide range of m
CRISPR-Cas9–mediated homology-directed DNA repair is the method of choice for precise gene editing in a wide range of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28368132401db8031f263b1847e6a9f
http://europepmc.org/articles/PMC7015686
http://europepmc.org/articles/PMC7015686
Autor:
J.M. Minina, Boris V. Skryabin, Alexey Korablev, Veniamin S. Fishman, Serova Ia, Inna E. Pristyazhnyuk, Oleg L. Serov, Timofey S. Rozhdestvensky, M.M. Gridina, Leonid Gubar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
In a previous study using one-step CRISPR/Cas9 genome editing in mouse zygotes, we created five founders carrying a 1,137 kb deletion and two founders carrying the same deletion, plus a 2,274 kb duplication involving the Cntn6 gene (encoding contacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3fa44fa4b1bbf7f09f7dfaaefb046a
https://pubmed.ncbi.nlm.nih.gov/31578377
https://pubmed.ncbi.nlm.nih.gov/31578377
Autor:
Anna Wolters, Timofey S. Rozhdestvensky, Boris V. Skryabin, Chenna R. Galiveti, Thomas Robeck, Birte Seeger, Carsten A. Raabe, Jürgen Brosius, Leonid Gubar
Publikováno v:
Scientific Reports
Prader-Willi syndrome (PWS) is a neurogenetic disorder caused by loss of paternally expressed genes on chromosome 15q11-q13. The PWS-critical region (PWScr) contains an array of non-protein coding IPW-A exons hosting intronic SNORD116 snoRNA genes. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ac4859ccf4fec82fac9955c3c4e5a7
https://doi.org/10.1038/srep20398
https://doi.org/10.1038/srep20398
Autor:
Boris V. Skryabin, Jana Pfeiffer, Jürgen Brosius, Sergej Handel, Leonid Gubar, Thomas Robeck, Birte Seeger, Elena Karpova, Timofey S. Rozhdestvensky
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 3, Iss 12, p e235 (2007)
PLoS Genetics, Vol 3, Iss 12, p e235 (2007)
Prader-Willi syndrome (PWS [MIM 176270]) is a neurogenetic disorder characterized by decreased fetal activity, muscular hypotonia, failure to thrive, short stature, obesity, mental retardation, and hypogonadotropic hypogonadism. It is caused by the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b9949aab4939f05ecc971924746f03
https://doi.org/10.1371/journal.pgen.0030235
https://doi.org/10.1371/journal.pgen.0030235