Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Leonid A. Yurkovetskiy"'
Autor:
Jean Lee, Leonid A. Yurkovetskiy, Derek Reiman, Lara Frommer, Zoe Strong, Anthony Chang, George J. Kahaly, Aly A. Khan, Alexander V. Chervonsky
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) display a strong female bias. Although sex hormones have been associated with protecting males from autoimmunity, the molecular mechanisms are incompletely understood. Here we re
Externí odkaz:
https://doaj.org/article/bc3a12679ae64cf6bc73934d3ee92974
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
Autor:
Matthew C. Funsten, Leonid A. Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H.F. Hansen, Katharine I. Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A. Antonopoulos, Gary M. Dunny, Ludvig M. Sollid, David Serreze, Aly A. Khan, Alexander V. Chervonsky
Publikováno v:
Cell Host & Microbe. 31:213-227.e9
Diet and commensals can affect the development of autoimmune diseases like type 1 diabetes (T1D). However, whether dietary interventions are microbe-mediated was unclear. We found that a diet based on hydrolyzed casein (HC) as a protein source protec