Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Leonhard Linta"'
Autor:
Ronan Russell, Marcus Ilg, Qiong Lin, Guangming Wu, André Lechel, Wendy Bergmann, Tim Eiseler, Leonhard Linta, Pavan Kumar P., Moritz Klingenstein, Kenjiro Adachi, Meike Hohwieler, Olena Sakk, Stefanie Raab, Anne Moon, Martin Zenke, Thomas Seufferlein, Hans R. Schöler, Anett Illing, Stefan Liebau, Alexander Kleger
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1155-1170 (2015)
Pluripotency represents a cell state comprising a fine-tuned pattern of transcription factor activity required for embryonic stem cell (ESC) self-renewal. TBX3 is the earliest expressed member of the T-box transcription factor family and is involved
Externí odkaz:
https://doaj.org/article/ab7f653a565f4e7696bb57ef1afd93c7
Autor:
Stefanie Pfaender, Karl Föhr, Anne-Kathrin Lutz, Stefan Putz, Kevin Achberger, Leonhard Linta, Stefan Liebau, Tobias M. Boeckers, Andreas M. Grabrucker
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Disturbances in neuronal differentiation and function are an underlying factor of many brain disorders. Zinc homeostasis and signaling are important mediators for a normal brain development and function, given that zinc deficiency was shown to result
Externí odkaz:
https://doaj.org/article/ae6fcb3ac2e34526aebd098301d867d4
Autor:
Moritz Klingenstein, Stefanie Raab, Kevin Achberger, Alexander Kleger, Stefan Liebau, Leonhard Linta
Publikováno v:
Stem Cells International, Vol 2016 (2016)
TBX3 is a member of the T-box transcription factor family and is involved in the core pluripotency network. Despite this role in the pluripotency network, its contribution to the reprogramming process during the generation of human induced pluripoten
Externí odkaz:
https://doaj.org/article/e747b74e6cbc4cac94fe9deeeb549a92
Publikováno v:
Stem Cells International, Vol 2014 (2014)
The breakthrough of reprogramming human somatic cells was achieved in 2006 by the work of Yamanaka and Takahashi. From this point, fibroblasts are the most commonly used primary somatic cell type for the generation of induced pluripotent stem cells (
Externí odkaz:
https://doaj.org/article/03b87caeceab4528a344ed2e35a53042
Autor:
Leonhard Linta, Marianne Stockmann, Qiong Lin, André Lechel, Christian Proepper, Tobias M. Boeckers, Alexander Kleger, Stefan Liebau
Publikováno v:
Stem Cells International, Vol 2013 (2013)
Ion channels are involved in a large variety of cellular processes including stem cell differentiation. Numerous families of ion channels are present in the organism which can be distinguished by means of, for example, ion selectivity, gating mechani
Externí odkaz:
https://doaj.org/article/22af6c40ef2e4745b80ca22015e2510b
Autor:
Anett Illing, Marianne Stockmann, Narasimha Swamy Telugu, Leonhard Linta, Ronan Russell, Martin Müller, Thomas Seufferlein, Stefan Liebau, Alexander Kleger
Publikováno v:
Stem Cells International, Vol 2013 (2013)
Pluripotent stem cells present an extraordinary powerful tool to investigate embryonic development in humans. Essentially, they provide a unique platform for dissecting the distinct mechanisms underlying pluripotency and subsequent lineage commitment
Externí odkaz:
https://doaj.org/article/0c4f390c577649219ddc6b4233e5b833
Publikováno v:
Stem Cells International, Vol 2012 (2012)
α-synuclein is a protein involved in the pathogenesis of several so-called synucleinopathies including Parkinson's disease. A variety of models have been so far assessed. Human induced pluripotent stem cells provide a patient- and disease-specific m
Externí odkaz:
https://doaj.org/article/2056692c31b04c1e90f803dc279ee7ce
Autor:
Stefan Liebau, Julie Steinestel, Leonhard Linta, Alexander Kleger, Alexander Storch, Michael Schoen, Konrad Steinestel, Christian Proepper, Juergen Bockmann, Michael J Schmeisser, Tobias M Boeckers
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18148 (2011)
BackgroundThe stabilization or regulated reorganization of the actin cytoskeleton is essential for cellular structure and function. Recently, we could show that the activation of the SK3-channel that represents the predominant SK-channel in neural st
Externí odkaz:
https://doaj.org/article/0e0ea8c5a24d4b38b35ba8be100c8676
Autor:
Stefan Liebau, Michael Tischendorf, Daniel Ansorge, Leonhard Linta, Marianne Stockmann, Clair Weidgang, Michelina Iacovino, Tobias Boeckers, Götz von Wichert, Michael Kyba, Alexander Kleger
Publikováno v:
Stem Cells International, Vol 2011 (2011)
Rationale. The family of calcium-activated potassium channels consists of four members with varying biological functions and conductances. Besides membrane potential modulation, SK channels have been found to be involved in cardiac pacemaker cell dev
Externí odkaz:
https://doaj.org/article/e6e7ead135324213af5ec967049fdfa7
Autor:
Tim Eiseler, Hans R. Schöler, Pavan Kumar, Alexander Kleger, Thomas Seufferlein, Kenjiro Adachi, Guangming Wu, Leonhard Linta, Ronan Russell, Stefanie Raab, Qiong Lin, André Lechel, Moritz Klingenstein, Martin Zenke, Meike Hohwieler, Olena Sakk, Wendy Bergmann, Stefan Liebau, Anne M Moon, Anett Illing, Marcus M. Ilg
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1155-1170 (2015)
Stem Cell Reports 5(6), 1155-1170 (2015). doi:10.1016/j.stemcr.2015.11.003
Stem Cell Reports
Stem Cell Reports 5(6), 1155-1170 (2015). doi:10.1016/j.stemcr.2015.11.003
Stem Cell Reports
Summary Pluripotency represents a cell state comprising a fine-tuned pattern of transcription factor activity required for embryonic stem cell (ESC) self-renewal. TBX3 is the earliest expressed member of the T-box transcription factor family and is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2530094f0051dca2a32d45b968246258
http://www.sciencedirect.com/science/article/pii/S2213671115003392
http://www.sciencedirect.com/science/article/pii/S2213671115003392