Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leonhard Heizinger"'
Autor:
Leonhard Heizinger, Andreas Fuchs, Stefan Dove, Regina Groebner-Ferreira, Helen Hoffmeister, Laura Strobl, Elizabeth A. Komives, Julian Nazet, Gernot Längst, Rainer Merkl
Publikováno v:
The FEBS Journal. 288:4000-4023
Chromatin remodelers use the energy of ATP hydrolysis to regulate chromatin dynamics. Their impact for development and disease requires strict enzymatic control. Here, we address the differential regulability of the ATPase domain of hSNF2H and hCHD3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d986b534418131a9ad7695620d566ab2
https://doi.org/10.1111/febs.15699
https://doi.org/10.1111/febs.15699
Autor:
Leonhard Heizinger, Rainer Merkl
A comparison of protein backbones makes clear that not more than approximately 1400 different folds exist, each specifying the three-dimensional topology of a protein domain. Large proteins are composed of specific domain combinations and many domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d68db37bf6ba515f87a2d7c8fda8b5b
Publikováno v:
Biochemistry. 58(22)
The members of the glutamine amidotransferase (GATase) family catalyze the incorporation of ammonia within numerous metabolic pathways and can be categorized in two classes. Here, we concentrated on class I GATases, which are heteromeric enzyme compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76aacc85fc6dd89eb6d88d1c5c8b302a
https://pubmed.ncbi.nlm.nih.gov/31117390
https://pubmed.ncbi.nlm.nih.gov/31117390
Autor:
Leonhard Heizinger, Eva Grauer, Rainer Merkl, Erdmute Kunstmann, Rajyalakshmi Meduri, Daniele Hasler, Utz Fischer, Reinhard Kalb, François M. Sement, Mo-Fang Liu, Gerhard Lehmann, Astrid Bruckmann, Gunter Meister, Zhi-Tong Li, Xin Wang, Mihaela Zavolan, Anne-Catherine Dock-Bregeon, Maciej Bąk
Publikováno v:
Molecular Cell. 77:1014-1031.e13
The La-related protein 7 (LARP7) forms a complex with the nuclear 7SK RNA to regulate RNA polymerase II transcription. It has been implicated in cancer and the Alazami syndrome, a severe developmental disorder. Here, we report a so far unknown role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e168287ef814173fd10486ed65352cf
https://doi.org/10.1016/j.molcel.2020.01.001
https://doi.org/10.1016/j.molcel.2020.01.001
Autor:
Uwe, Schwartz, Attila, Németh, Sarah, Diermeier, Josef H, Exler, Stefan, Hansch, Rodrigo, Maldonado, Leonhard, Heizinger, Rainer, Merkl, Gernot, Längst
Publikováno v:
Nucleic Acids Research
Packaging of DNA into chromatin regulates DNA accessibility and consequently all DNA-dependent processes. The nucleosome is the basic packaging unit of DNA forming arrays that are suggested, by biochemical studies, to fold hierarchically into ordered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4f71ad787033d77592d319c489e4113
https://pubmed.ncbi.nlm.nih.gov/30496478
https://pubmed.ncbi.nlm.nih.gov/30496478
Autor:
Stefan Hansch, Josef H. Exler, Rodrigo Maldonado, Gernot Längst, Rainer Merkl, Leonhard Heizinger, Attila Németh, Uwe Schwartz, Sarah D. Diermeier
Packaging of DNA into chromatin regulates DNA accessibility and, consequently, all DNA-dependent processes, such as transcription, recombination, repair, and replication. The nucleosome is the basic packaging unit of DNA forming arrays that are sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9819860e2955f7d74831366f179b820c
Autor:
Markus Busch, Leonhard Heizinger, Florian Busch, Rainer Merkl, Maximilian G. Plach, Florian Semmelmann, Vicki H. Wysocki, Reinhard Sterner
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Cells contain a multitude of protein complexes whose subunits interact with high specificity. However, the number of different protein folds and interface geometries found in nature is limited. This raises the question of how protein-protein interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa5be9138207b1e57152fc63822dba3
https://doi.org/10.1073/pnas.1707335114
https://doi.org/10.1073/pnas.1707335114
Autor:
Franziska C. Vogl, Inga Schlecht, Sebastian Mehrl, Gckd Study Investigators, Nadine Nürnberger, Kai-Uwe Eckardt, Peter J. Oefner, Michael F. Leitzmann, Lisa Ellmann, Wolfram Gronwald, Jerome Rossert, Leonhard Heizinger, Helena U. Zacharias, Katja Dettmer
Publikováno v:
Analytical and bioanalytical chemistry. 408(29)
Reliable identification of features distinguishing biological groups of interest in urinary metabolite fingerprints requires the control of total metabolite abundance, which may vary significantly as the kidneys adjust the excretion of water and solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd632728385a54b7e7f52dc7e06c3d8
https://pubmed.ncbi.nlm.nih.gov/27815612
https://pubmed.ncbi.nlm.nih.gov/27815612
Autor:
Sarah, Diermeier, Petros, Kolovos, Leonhard, Heizinger, Uwe, Schwartz, Theodore, Georgomanolis, Anne, Zirkel, Gero, Wedemann, Frank, Grosveld, Tobias A, Knoch, Rainer, Merkl, Peter R, Cook, Gernot, Längst, Argyris, Papantonis
Publikováno v:
Genome Biology
Background The rearrangement of nucleosomes along the DNA fiber profoundly affects gene expression, but little is known about how signalling reshapes the chromatin landscape, in three-dimensional space and over time, to allow establishment of new tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3706b3776a6187e2e2f4d4a027d687c1
https://pubmed.ncbi.nlm.nih.gov/25608606
https://pubmed.ncbi.nlm.nih.gov/25608606