Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Leongamornlert, DA"'
Autor:
Mijuskovic, M, Saunders, EJ, Leongamornlert, DA, Wakerell, S, Whitmore, I, Dadaev, T, Cieza-Borrella, C, Govindasami, K, Brook, MN, Haiman, CA, Conti, DV, Eeles, RA, Kote-Jarai, Z
Publikováno v:
British Journal of Cancer
Background\ud Prostate cancer (PrCa) demonstrates a heterogeneous clinical presentation ranging from largely indolent to lethal. We sought to identify a signature of rare inherited variants that distinguishes between these two extreme phenotypes.\ud
Autor:
Dadaev, T, Saunders, EJ, Newcombe, PJ, Anokian, E, Leongamornlert, DA, Brook, MN, Cieza-Borrella, C, Mijuskovic, M, Wakerell, S, Olama, AAA, Schumacher, FR, Berndt, SI, Benlloch, S, Ahmed, M, Goh, C, Sheng, X, Zhang, Z, Muir, K, Govindasami, K, Lophatananon, A, Stevens, VL, Gapstur, SM, Carter, BD, Tangen, CM, Goodman, P, Thompson, IM, Batra, J, Chambers, S, Moya, L, Clements, J, Horvath, L, Tilley, W, Risbridger, G, Gronberg, H, Aly, M, Nordström, T, Pharoah, P, Pashayan, N, Schleutker, J, Tammela, TLJ, Sipeky, C, Auvinen, A, Albanes, D, Weinstein, S, Wolk, A, Hakansson, N, West, C, Dunning, AM, Burnet, N, Mucci, L, Giovannucci, E, Andriole, G, Cussenot, O, Cancel-Tassin, G, Koutros, S, Freeman, LEB, Sorensen, KD, Orntoft, TF, Borre, M, Maehle, L, Grindedal, EM, Neal, DE, Donovan, JL, Hamdy, FC, Martin, RM, Travis, RC, Key, TJ, Hamilton, RJ, Fleshner, NE, Finelli, A, Ingles, SA, Stern, MC, Rosenstein, B, Kerns, S, Ostrer, H, Lu, Y-J, Zhang, H-W, Feng, N, Mao, X, Guo, X, Wang, G, Sun, Z, Giles, GG, Southey, MC, Macinnis, RJ, Fitzgerald, LM, Kibel, AS, Drake, BF, Vega, A, Gómez-Caamaño, A, Fachal, L, Szulkin, R, Eklund, M, Kogevinas, M, Llorca, J, Castaño-Vinyals, G, Penney, KL, Stampfer, M, Park, JY, Sellers, TA, Lin, H-Y, Stanford, JL, Cybulski, C, Wokolorczyk, D, Lubinski, J, Ostrander, EA, Geybels, MS, Nordestgaard, BG, Nielsen, SF, Weisher, M, Bisbjerg, R, Røder, MA, Iversen, P, Brenner, H, Cuk, K, Holleczek, B, Maier, C, Luedeke, M, Schnoeller, T, Kim, J, Logothetis, CJ, John, EM, Teixeira, MR, Paulo, P, Cardoso, M, Neuhausen, SL, Steele, L, Ding, YC, De Ruyck, K, De Meerleer, G, Ost, P, Razack, A, Lim, J, Teo, S-H, Lin, DW, Newcomb, LF, Lessel, D, Gamulin, M, Kulis, T, Kaneva, R, Usmani, N, Slavov, C, Mitev, V, Parliament, M, Singhal, S, Claessens, F, Joniau, S, Van Den Broeck, T, Larkin, S, Townsend, PA, Aukim-Hastie, C, Gago-Dominguez, M, Castelao, JE, Martinez, ME, Roobol, MJ, Jenster, G, Van Schaik, RHN, Menegaux, F, Truong, T, Koudou, YA, Xu, J, Khaw, K-T, Cannon-Albright, L, Pandha, H, Michael, A, Kierzek, A, Thibodeau, SN, McDonnell, SK, Schaid, DJ, Lindstrom, S, Turman, C, Ma, J, Hunter, DJ, Riboli, E, Siddiq, A, Canzian, F, Kolonel, LN, Le Marchand, L, Hoover, RN, Machiela, MJ, Kraft, P, Consortium, Practical (Prostate Cancer Association Group To Investigate Cancer-Associated Alterations In The Genome), Freedman, M, Wiklund, F, Chanock, S, Henderson, BE, Easton, DF, Haiman, CA, Eeles, RA, Conti, DV, Kote-Jarai, Z
Publikováno v:
Nature Communications, 9:2256. Nature Publishing Group
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
NATURE COMMUNICATIONS
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0bf073e818a65d824db9940163b4958c
https://www.repository.cam.ac.uk/handle/1810/278592
https://www.repository.cam.ac.uk/handle/1810/278592
Autor:
Saunders, EJ, Dadaev, T, Leongamornlert, DA, Olama, AA, Benlloch, S, Giles, GG, Wiklund, F, Grönberg, H, Haiman, CA, Schleutker, J, Nordestgaard, BG, Travis, RC, Neal, D, Pasayan, N, Khaw, KT, Stanford, JL, Blot, WJ, Thibodeau, SN, Maier, C, Kibel, AS, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, JY, Kaneva, R, Batra, J, Teixeira, MR, Pandha, H, Govindasami, K, Muir, K, Genetic Prostate Cancer Study Collaborators, UK, ProtecT Study Collaborators, UK, Consortium, PRACTICAL, Easton, DF, Eeles, RA, Kote-Jarai, Z
BACKGROUND: Germline mutations within DNA-repair genes are implicated in susceptibility to multiple forms of cancer. For prostate cancer (PrCa), rare mutations in BRCA2 and BRCA1 give rise to moderately elevated risk, whereas two of ∼100 common, lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::88c60b9a74f2d10a40f116c3dd3a86bc
https://www.repository.cam.ac.uk/handle/1810/255991
https://www.repository.cam.ac.uk/handle/1810/255991
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Autor:
Kote-Jarai Z; The Institute of Cancer Research, London, UK. Electronic address: zsofia.kote-jarai@icr.ac.uk., Leongamornlert DA; The Institute of Cancer Research, London, UK., Saunders EJ; The Institute of Cancer Research, London, UK., Conti DV; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, USA., Eeles RA; The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK.
Publikováno v:
European urology [Eur Urol] 2019 Nov; Vol. 76 (5), pp. e130-e131. Date of Electronic Publication: 2019 Jun 22.
Autor:
Leongamornlert DA; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Saunders EJ; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Wakerell S; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Whitmore I; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Dadaev T; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Cieza-Borrella C; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Benafif S; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Brook MN; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Donovan JL; School of Social and Community Medicine, University of Bristol, Bristol, UK., Hamdy FC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Faculty of Medical Science, John Radcliffe Hospital, University of Oxford, Oxford, UK., Neal DE; Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK; Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Muir K; Division of Population Health, University of Manchester, Manchester, UK., Govindasami K; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Conti DV; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, USA., Kote-Jarai Z; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Electronic address: zsofia.kote-jarai@icr.ac.uk., Eeles RA; Oncogenetics, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK.
Publikováno v:
European urology [Eur Urol] 2019 Sep; Vol. 76 (3), pp. 329-337. Date of Electronic Publication: 2019 Feb 15.