Zobrazeno 1 - 10
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pro vyhledávání: '"Leonenko, Zoya"'
Alzheimer's disease (AD) is a neurodegenerative disease characterized by dementia and memory loss in the elderly population. The amyloid-$\beta$ peptide (A$\beta$ 1-42) is one of the main pathogenic factors in AD and is known to cause damage to neuro
Externí odkaz:
http://arxiv.org/abs/2401.05878
Publikováno v:
In Biochemistry and Biophysics Reports July 2023 34
Akademický článek
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Autor:
Deol, Harmeen K., Broom, Helen R., Siebeneichler, Bruna, Lee, Brenda, Leonenko, Zoya, Meiering, Elizabeth M.
Publikováno v:
In Biophysical Chemistry September 2022 288
Stress-induced glucocorticoid elevation is a highly conserved response among vertebrates. This facilitates stress adaptation and the mode of action involves activation of the intracellular glucocorticoid receptor leading to the modulation of target g
Externí odkaz:
http://arxiv.org/abs/1704.08321
Using atomic force microscopy (AFM) we investigated the interaction of amyloid beta (Ab) (1 42) peptide with chemically modified surfaces in order to better understand the mechanism of amyloid toxicity, which involves interaction of amyloid with cell
Externí odkaz:
http://arxiv.org/abs/1704.08319
Autor:
Hane, Francis, Leonenko, Zoya
Metal ions, including copper and zinc, have been implicated in the pathogenesis of Alzheimers disease through a variety of mechanisms including increased amyloid \b{eta} affinity and redox effects. Recent reports have demonstrated that the amyloid \b
Externí odkaz:
http://arxiv.org/abs/1704.08315
Thiol self assembled monolayers (SAMs) are widely used in many nano- and bio-technology applications. We report a new approach to create and characterize a thiol SAMs micropattern with alternating charges on a flat goldcoated substrate using atomic f
Externí odkaz:
http://arxiv.org/abs/1704.08320
The link between metals, Alzheimers disease (AD) and its implicated protein, amyloid \b{eta} (A\b{eta}), is complex and highly studied. AD is believed to occur as a result of the misfolding and aggregation of A\b{eta}. The dyshomeostasis of metal ion
Externí odkaz:
http://arxiv.org/abs/1704.08317
Alzheimer's disease (AD) is a devastating neurodegenerative disorder with no cure and limited treatment solutions that are unable to target any of the suspected causes. Increasing evidence suggests that one of the causes of neurodegeneration is the o
Externí odkaz:
http://arxiv.org/abs/1704.08313