Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Leone S. Hopkins"'
Autor:
Dylan T. Ammons, Leone S. Hopkins, Kathryn E. Cronise, Jade Kurihara, Daniel P. Regan, Steven Dow
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME).
Externí odkaz:
https://doaj.org/article/a117ed88309245d08834c3feb15089c6
Autor:
Dylan T. Ammons, R. Adam Harris, Leone S. Hopkins, Jade Kurihara, Kristen Weishaar, Steven Dow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Translationally relevant animal models are essential for the successful translation of basic science findings into clinical medicine. While rodent models are widely accessible, there are numerous limitations that prevent the extrapolation of findings
Externí odkaz:
https://doaj.org/article/4e178151f4cd495ba5b374f5cd16bee7
Autor:
Aimee C. Colbath, Steven W. Dow, Leone S. Hopkins, Jennifer N. Phillips, C. Wayne McIlwraith, Laurie R. Goodrich
Publikováno v:
Frontiers in Veterinary Science, Vol 5 (2018)
Background: The effects of recombinant interleukin-1β (rIL-1β) have been described for the middle carpal joint (MCJ). However, we are unaware of any studies that have described the cytological response of the tibiotarsal joint (TTJ) to rIL-1β or c
Externí odkaz:
https://doaj.org/article/22ce5e236da74fbbac961d595484d411
Autor:
Leone S. Hopkins, Aimee C. Colbath, Laurie R. Goodrich, Jennifer N Phillips, Steven W. Dow, C. W. McILWRAITH
Publikováno v:
Equine Veterinary Journal. 52:144-151
Background Allogeneic bone marrow-derived mesenchymal stem cells (BMDMSCs) could provide multiple advantages over autologous BMDMSCs, including creating an 'off-the-shelf' treatment together with the ability to control for donor variation. Objectives
Autor:
Genevieve Hartley, Leone S. Hopkins, Steven W. Dow, Amanda Guth, Brent Murphy, Robyn E. Elmslie
Publikováno v:
Veterinary and Comparative Oncology. 17:69-79
Cancer relapse following chemotherapy has been attributed in part to the presence of cancer stem cells (CSC), which drive tumor growth and metastasis and are highly resistant to the effects of cytotoxic chemotherapy. As a result, treatment with cytot
Autor:
Jennifer N Phillips, C. Wayne McIlwraith, Aimee C. Colbath, Laurie R. Goodrich, Leone S. Hopkins, Steven W. Dow
Publikováno v:
Equine Vet J
Background Allogeneic and autologous bone marrow-derived mesenchymal stem cells (BMDMSCs) have been administered in equine joints for their anti-inflammatory effects. However, allogeneic BMDMSC offer multiple clinical and practical advantages. Theref
Autor:
Jonathan Coy, Jennifer R. Hawley, Rod A.W. Rosychuk, Leone S. Hopkins, Steven W. Dow, Michael R. Lappin, Elena T. Contreras, Jennifer R. Schissler, Clarissa Pimentel de Souza
Publikováno v:
Veterinary Dermatology. 29:482-e162
BACKGROUND: Juvenile onset generalized demodicosis (JOGD) is thought to occur due to immunological abnormalities and is over‐represented in pit bull terrier‐type dogs. ANIMALS: Twelve pit bull terrier‐type dogs with JOGD and 12 age‐matched he