Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Leonardo Pignataro"'
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/8f9a62a2936045088659b8de560b7ec1
Autor:
Leonardo Pignataro
Publikováno v:
Neuroscience Letters. 713:134507
Although alcohol abuse and dependence have profound negative health consequences, emerging evidence suggests that exposure to low/moderate concentrations of ethanol protects multiple organs and systems. In the CNS, moderate drinking decreases the ris
Autor:
Lindsay Tannenholz, Neil L. Harrison, Florence P. Varodayan, Leonardo Pignataro, Petr Protiva
Publikováno v:
Brain and Behavior
Astrocytes are critical for maintaining homeostasis in the central nervous system (CNS), and also participate in the genomic response of the brain to drugs of abuse, including alcohol. In this study, we investigated ethanol regulation of gene express
Publikováno v:
Neuroscience. 193:63-71
Many synapses within the central nervous system are sensitive to ethanol. Although alcohol is known to affect the probability of neurotransmitter release in specific brain regions, the effects of alcohol on the underlying synaptic vesicle fusion mach
Publikováno v:
Alcohol. 41:177-185
The inhibitory neurotransmitter gamma-aminobutyric acid (GABA) has long been implicated in the anxiolytic, amnesic, and sedative behavioral effects of alcohol. A large number of studies have investigated the interactions of alcohol with GABA receptor
Autor:
Leonardo Pignataro, Thomas Pannicke, Robert E. Marc, Kohichi Tanaka, Takayuki Harada, Andreas Reichenbach, Vijay P. Sarthy, Michael Weick
Publikováno v:
Glia. 49:184-196
Glutamate transporters are involved in maintaining extracellular glutamate at a low level to ensure a high signal-to-noise ratio for glutamatergic neurotransmission and to protect neurons from excitotoxic damage. The mammalian retina is known to expr
Publikováno v:
NeuroReport. 15:1895-1898
Neuronal glutamate transporters have been shown to play a role in GABA synthesis by enhancing glutamate uptake. In the present study, we have examined whether a glial glutamate transporter, GLAST, has a role in GABA synthesis in the mammalian retina.
Publikováno v:
Brain Research. 902:74-81
We investigated the effects of in ovo chronic administration of the endogenous neurosteroid epipregnanolone (5beta-pregnan-3beta-ol-20-one) on the GABA(A) receptor complex present in chick optic lobe synaptic membranes. Chronic epipregnanolone treatm
Publikováno v:
International Journal of Developmental Neuroscience. 16:433-442
It has been demonstrated in different vertebrate species that the GABAA receptor complex is modulated by certain steroids. Theses results prompted work on the synthesis of these neurosteroids in the Central Nervous System. However, there are scarcely
Publikováno v:
Neurochemical Research. 23:1395-1401
In the present paper we describe the presence in avian CNS of an endogenous inhibitor of [3H]flunitrazepam binding. This compound was extracted from a synaptic membrane fraction isolated from chick optic lobe and brain using an exhaustive aqueous was