Výsledky vyhledávání - "Leonardo Pasalic"

Akademický článek

Should multiple factor dilutions be performed for all patient coagulation factor assays? Let the debate begin!

Autor: Emmanuel J. Favaloro, Leonardo Pasalic

Publikováno v: Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 2, Pp n/a-n/a (2022)

Abstract Laboratory assessment of blood coagulation factors may be undertaken for various reasons, including investigating the possibility of hemophilia or unexpected prolongation in routine coagulation assays (eg, prothrombin time, activated partial

Externí odkaz: https://doaj.org/article/6b466fb5d9a94e37be66314df7bb1fd8

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Akademický článek

Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants

Autor: Emmanuel J. Favaloro, Leonardo Pasalic

Publikováno v: Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 2, Pp n/a-n/a (2022)

Abstract Background Lupus anticoagulants (LA) are one laboratory criterion for classification of antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal morbidity being clinical criteria. The presence of LA is detected

Externí odkaz: https://doaj.org/article/a106d917b6c24f29990599ae691ad72f

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Akademický článek

Advanced Flow Cytometry Using the SYTO-13 Dye for the Assessment of Platelet Reactivity and Maturity in Whole Blood

Autor: Oliver Buchhave Pedersen, Leonardo Pasalic, Erik Lerkevang Grove, Steen Dalby Kristensen, Anne-Mette Hvas, Peter H. Nissen

Publikováno v: Methods and Protocols, Vol 6, Iss 1, p 8 (2023)

Newly produced immature platelets are larger, contain higher amounts of residual RNA, and are more reactive than mature platelets. Flow cytometry using the SYTO-13 dye is a method for the subdivision of immature platelets from mature platelets based

Externí odkaz: https://doaj.org/article/bec3d7b5969345e7ba850cb9e7d629df

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Akademický článek

Antibodies against Platelet Factor 4 and Their Associated Pathologies: From HIT/HITT to Spontaneous HIT-Like Syndrome, to COVID-19, to VITT/TTS

Autor: Emmanuel J. Favaloro, Leonardo Pasalic, Giuseppe Lippi

Publikováno v: Antibodies, Vol 11, Iss 1, p 7 (2022)

Antibodies against platelet factor 4 (PF4), a protein released from alpha-granules of activated platelets, may cause a number of pathophysiological conditions. The most commonly known is heparin-induced thrombocytopenia (HIT), which develops in a sma

Externí odkaz: https://doaj.org/article/b954756ddedd4334b97c4a142438d982

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Akademický článek

The Intriguing Relationships of von Willebrand Factor, ADAMTS13 and Cardiac Disease

Autor: Benjamin Reardon, Leonardo Pasalic, Emmanuel J. Favaloro

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 8, Iss 9, p 115 (2021)

von Willebrand factor (VWF) is an adhesive protein involved in primary hemostasis and facilitates platelet adhesion to sites of vascular injury, thereby promoting thrombus formation. VWF exists in plasma as multimers of increasing size, with the larg

Externí odkaz: https://doaj.org/article/2c010d86da99483ca54175bc8516c01b

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Akademický článek

Why Do Patients Bleed?

Autor: Jennifer Curnow, Leonardo Pasalic, Emmanuel J. Favaloro

Publikováno v: The Surgery Journal, Vol 02, Iss 01, Pp e29-e43 (2016)

Abstract Patients undergoing surgical procedures can bleed for a variety of reasons. Assuming that the surgical procedure has progressed well and that the surgeon can exclude surgical reasons for the unexpected bleeding, then the bleeding may be due

Externí odkaz: https://doaj.org/article/e7d775aae5754f4ba09783a772d78a2c

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