Výsledky vyhledávání - "Leonardo N, Seito"

Akademický článek

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1

Autor: Suwellen S. D. de Azevedo, Marcelo Ribeiro-Alves, Fernanda H. Côrtes, Edson Delatorre, Lucia Spangenberg, Hugo Naya, Leonardo N. Seito, Brenda Hoagland, Beatriz Grinsztejn, Valdilea G. Veloso, Mariza G. Morgado, Thiago Moreno L. Souza, Gonzalo Bello

Publikováno v: Retrovirology, Vol 17, Iss 1, Pp 1-14 (2020)

Abstract Background Some multifunctional cellular proteins, as the monocyte chemotactic protein-induced protein 1 (ZC3H12A/MCPIP1) and the cyclin-dependent kinase inhibitor CDKN1A/p21, are able to modulate the cellular susceptibility to the human imm

Externí odkaz: https://doaj.org/article/d514b7d1703e4627bd3848ea9bb820cb

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Akademický článek

Effect of Gedunin on Acute Articular Inflammation and Hypernociception in Mice

Autor: Fernando P. Conte, Fausto K. Ferraris, Thadeu E. M. M. Costa, Patricia Pacheco, Leonardo N. Seito, Waldiceu A. Verri Jr., Fernando Q. Cunha, Carmen Penido, Maria G. Henriques

Publikováno v: Molecules, Vol 20, Iss 2, Pp 2636-2657 (2015)

Gedunin, a natural limonoid from Meliaceae species, has been previously described as an antiinflammatory compound in experimental models of allergic inflammation. Here, we report the antiinflammatory and antinociceptive effects of gedunin in an acute

Externí odkaz: https://doaj.org/article/6a381e763c8c4fb28e3bbef2ccb63794

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Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways

Autor: Waldiceu A. Verri, Leonardo N. Seito, Maria das Graças M. O. Henriques, Luana Barbosa Correa, Elaine Cruz Rosas, Marília F. Manchope, Thiago M. Cunha

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Methyl gallate (MG) is a prevalent polyphenol in the plant kingdom, which may be related to the effects of several medicinal plants. Although it is widely reported that polyphenols have therapeutic effects, there are few studies demonstrating that MG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786b2dfd0cd25ca6936de621b85d4750
https://doi.org/10.1007/s00011-020-01407-0

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Antimalarial and anti-inflammatory activities of new chloroquine and primaquine hybrids: Targeting the blockade of malaria parasite transmission

Autor: Elaine Cruz Rosas, Maria de Lourdes G. Ferreira, Nubia Boechat, Paula M. Sa, Leonardo N. Seito, Rita de C. C. Carvalho, Julia Penna Coutinho, Antoniana U. Krettli, Mônica M. Bastos, Luiz C. S. Pinheiro

Publikováno v: Bioorganicmedicinal chemistry. 28(24)

Malaria is a disease that requires new drugs not only to fight Plasmodium but also to reduce symptoms of infection such as fever and inflammation. A series of 21 hybrid compounds were designed from chloroquine (CQ) and primaquine (PQ) linked to the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0de9d7803fab45f78e39bbd4c56e35
https://pubmed.ncbi.nlm.nih.gov/33166927

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Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1

Autor: Beatriz Grinsztejn, Marcelo Ribeiro-Alves, Edson Delatorre, Fernanda Heloise Côrtes, Gonzalo Bello, Leonardo N. Seito, Brenda Hoagland, Valdilea G. Veloso, Mariza G. Morgado, Lucía Spangenberg, Thiago Moreno L. Souza, Hugo Naya, Suwellen S D de Azevedo

Publikováno v: Retrovirology
Retrovirology, Vol 17, Iss 1, Pp 1-14 (2020)

Background Some multifunctional cellular proteins, as the monocyte chemotactic protein-induced protein 1 (ZC3H12A/MCPIP1) and the cyclin-dependent kinase inhibitor CDKN1A/p21, are able to modulate the cellular susceptibility to the human immunodefici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded3879f40fd3469f367d7d977fc2c4d
https://doi.org/10.1186/s12977-020-00522-4

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Thiophenacetamide as a potential modulator to NF-κB: structure and dynamics study using in silico and molecular biology assays

Autor: Ernesto Raul Caffarena, Leonardo N. Seito, Fátima M.F. Vergara, Maria das Graças M. O. Henriques, Vanessa S. Silva, Lucianna Helene Santos, Deborah Antunes

Publikováno v: Journal of Biomolecular Structure and Dynamics. 37:4395-4406

Nuclear factor kappa B (NF-κB) plays critical roles in the regulation of many pathophysiological processes, including inflammation and immune responses, cell growth and apoptosis. This DNA-binding protein receptor is considered an important molecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86509b3cfd4049ccaab7bf80b995eb3c
https://doi.org/10.1080/07391102.2018.1552623

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Thiophenacetamide as a potential modulator to NF-κB: structure and dynamics study using

Autor: Vanessa S, Silva, Fatima M, Vergara, Leonardo N, Seito, Deborah, Antunes, Lucianna H S, Santos, Maria G, Henriques, Ernesto R, Caffarena

Publikováno v: Journal of biomolecular structuredynamics. 37(16)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::64184d33aaf5e756cea6f7b4b2d3a6ba
https://pubmed.ncbi.nlm.nih.gov/30486742

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Effect of Gedunin on Acute Articular Inflammation and Hypernociception in Mice

Autor: Fausto Klabund Ferraris, Carmen Penido, Fernando de Paiva Conte, Waldiceu A. Verri, Fernando Q. Cunha, Patricia Pacheco, Thadeu Estevam Moreira Maramaldo Costa, Leonardo N. Seito, Maria das Graças M. O. Henriques

Publikováno v: Molecules
Volume 20
Issue 2
Pages 2636-2657
Molecules, Vol 20, Iss 2, Pp 2636-2657 (2015)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc4c33e68c165db81ef57c5a51a0541
https://doi.org/10.3390/molecules20022636

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Lipoxin A4 attenuates endothelial dysfunction during experimental cerebral malaria

Autor: Maria Fernanda de Souza Costa, Leonardo J M Carvalho, Maria das Graças M. O. Henriques, André L. P. Candéa, Eduardo Tibiriçá, Leonardo N. Seito, Natalia Torres, Vanessa Estato, Ana Acacia S. Pinheiro, Carmen Penido, Barbara Antunes, Celso Caruso-Neves, Leandro L. da Silva, Mariana C. Souza, Thadeu Maramaldo, Tatiana Almeida Pádua

Publikováno v: International Immunopharmacology. 24(2):400-407

A breakdown of the brain–blood barrier (BBB) due to endothelial dysfunction is a primary feature of cerebral malaria (CM). Lipoxins (LX) are specialized pro-resolving mediators that attenuate endothelial dysfunction in different vascular beds. It h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c8c4e1c837b5423debd10e96773b36

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Anti-inflammatory Effect of Methyl Gallate on Experimental Arthritis: Inhibition of Neutrophil Recruitment, Production of Inflammatory Mediators, and Activation of Macrophages

Autor: Tatiana Almeida Pádua, André L. P. Candéa, Magaiver Andrade Silva, Maria das Graças M. O. Henriques, Elaine Cruz Rosas, Luana Barbosa Correa, Leonardo N. Seito, Thadeu Estevam Moreira Maramaldo Costa

Publikováno v: Journal of natural products. 79(6)

Methyl gallate (MG) is a prevalent phenolic acid in the plant kingdom, and its presence in herbal medicines might be related to its remarkable biological effects, such as its antioxidant, antitumor, and antimicrobial activities. Although some indirec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c43bbbd63dc49972fe146989c269ac6
https://pubmed.ncbi.nlm.nih.gov/27227459

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