Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Leonardo M. Saraiva"'
Autor:
Victor Bodart-Santos, Luiza R. P. de Carvalho, Mariana A. de Godoy, André F. Batista, Leonardo M. Saraiva, Luize G. Lima, Carla Andreia Abreu, Fernanda G. De Felice, Antonio Galina, Rosalia Mendez-Otero, Sergio T. Ferreira
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Background Mesenchymal stem cells (MSCs) have been explored as promising tools for treatment of several neurological and neurodegenerative diseases. MSCs release abundant extracellular vesicles (EVs) containing a variety of biomolecules, inc
Externí odkaz:
https://doaj.org/article/6fd8843a30e946229814dae1d5a03890
Autor:
Antonio Galina, Sergio T. Ferreira, Luize G. Lima, Luiza Rachel Pinheiro de Carvalho, Victor Bodart-Santos, Rosalia Mendez-Otero, Fernanda G. De Felice, Mariana Araya de Godoy, Carla Andreia Abreu, Andre F. Batista, Leonardo M. Saraiva
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
BackgroundMesenchymal stem cells (MSCs) have been explored as promising tools for treatment of several neurological and neurodegenerative diseases. MSCs release abundant extracellular vesicles (EVs) containing a variety of biomolecules, including mRN
Autor:
Jose Henrique Ledo, Carine V Costa, Julia R. Clarke, Helen M. Melo, Fernanda G. De Felice, Sergio T. Ferreira, Leonardo M. Saraiva, Adriano Sebollela, Axa P Mota-Sales, Felipe C. Ribeiro, William L. Klein, Cláudia P. Figueiredo
Publikováno v:
Journal of Neuroscience. 33:9626-9634
Brain accumulation of soluble amyloid-β oligomers (AβOs) has been implicated in synapse failure and cognitive impairment in Alzheimer's disease (AD). However, whether and how oligomers of different sizes induce synapse dysfunction is a matter of co
Autor:
Carlla Silva, Livian Rocha, Carolina A. Braga, Antonio Galina, Leonardo M. Saraiva, Leandro Cardoso Sinis, Adalberto Vieyra, Rosalia Mendez-Otero, Victor H.S. Monteiro, Hellen J V Beiral, Mariana Araya de Godoy, Sergio T. Ferreira, Fernanda G. De Felice, Luiza Rachel Pinheiro de Carvalho, Renata B. Leal, Narcisa L. Cunha-e-Silva, Andréia Vasconcelos-dos-Santos
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Rosalia Mendez-Otero, Leonardo M. Saraiva, Victor Bodart, Mariana Araya de Godoy, Luiza Rachel Pinheiro de Carvalho, Turán P. Ürményi, Rafael Soares, Sergio T. Ferreira, Antonio Galina
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Fabio A. Mendes, Margaret H. Magdesian, Sergio T. Ferreira, Maria A. Juliano, Leonardo M. Saraiva, Luiz Juliano, José Garcia-Abreu, Milena M. V. F. Carvalho
Publikováno v:
Journal of Biological Chemistry. 283:9359-9368
The amyloid-beta peptide (Abeta) plays a major role in neuronal dysfunction and neurotoxicity in Alzheimer disease. However, the signal transduction mechanisms involved in Abeta-induced neuronal dysfunction remain to be fully elucidated. A major curr
Autor:
Sergio T. Ferreira, Leonardo M. Saraiva, Jean-Christophe Houzel, Leticia Forny-Germano, Marcelo N. N. Vieira, Fernanda G. De Felice, Adriano Sebollela, Ana Maria Blanco Martinez
Publikováno v:
Journal of Neurochemistry. 103:736-748
Protein aggregation and amyloid accumulation in different tissues are associated with cellular dysfunction and toxicity in important human pathologies, including Alzheimer's disease and various forms of systemic amyloidosis. Soluble oligomers formed
Autor:
Carine V Costa, Axa P Mota-Sales, William L. Klein, Cláudia P. Figueiredo, Jose Henrique Ledo, Julia R. Clarke, Sergio T. Ferreira, Helen M. Melo, Fernanda G. De Felice, Leonardo M. Saraiva, Felipe Ribeiro, Adriano Sebollela
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
Samantha M. Martins, Sergio T. Ferreira, Helena Brentani, Fabio F. Oliveira, Léo Freitas-Correa, Dirce Maria Carraro, Fernanda G. De Felice, Soniza Vieira Alves-Leon, Andrea C. Paula-Lima, Leonardo M. Saraiva, Cesar Torres, Adriano Sebollela, Louise Danielle de Carvalho Mota, Jorge Marcondes de Souza
Publikováno v:
The Journal of biological chemistry. 287(10)
Cognitive decline in Alzheimer disease (AD) is increasingly attributed to the neuronal impact of soluble oligomers of the amyloid-β peptide (AβOs). Current knowledge on the molecular and cellular mechanisms underlying the toxicity of AβOs stems la
Autor:
Marcelo N N, Vieira, Letícia, Forny-Germano, Leonardo M, Saraiva, Adriano, Sebollela, Ana M Blanco, Martinez, Jean-Christophe, Houzel, Fernanda G, De Felice, Sérgio T, Ferreira
Publikováno v:
Journal of neurochemistry. 103(2)
Protein aggregation and amyloid accumulation in different tissues are associated with cellular dysfunction and toxicity in important human pathologies, including Alzheimer's disease and various forms of systemic amyloidosis. Soluble oligomers formed