Kinetics of rhodopsin deactivation and its role in regulating recovery and reproducibility of rod photoresponse.

Autor: Giovanni Caruso, Paolo Bisegna, Leonardo Lenoci, Daniele Andreucci, Vsevolod V Gurevich, Heidi E Hamm, Emmanuele DiBenedetto

Publikováno v: PLoS Computational Biology, Vol 6, Iss 12, p e1001031 (2010)

The single photon response (SPR) in vertebrate phototransduction is regulated by the dynamics of R* during its lifetime, including the random number of phosphorylations, the catalytic activity and the random sojourn time at each phosphorylation level

Externí odkaz: https://doaj.org/article/93559d2c15bf42c2b279a662f346b539

Identification of key factors that reduce the variability of the single photon response

Autor: Paolo Bisegna, Heidi E. Hamm, Giovanni Caruso, Daniele Andreucci, Emmanuele DiBenedetto, Vsevolod V. Gurevich, Leonardo Lenoci

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 108 (2011): 7804–7807. doi:10.1073/pnas.1018960108
info:cnr-pdr/source/autori:G. Caruso, P. Bisegna, D. Andreucci, L. Lenoci, V.V. Gurevich, H.E. Hamm, E. DiBenedetto/titolo:“Identification of key factors that reduce the variability of the single photon respons/doi:10.1073%2Fpnas.1018960108/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2011/pagina_da:7804/pagina_a:7807/intervallo_pagine:7804–7807/volume:108

Rod photoreceptors mediate vision in dim light. Their biological function is to discriminate between distinct, very low levels of illumination, i.e., they serve as reliable photon counters. This role requires high reproducibility of the response to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa015f40d069d68a2a044581c55cfc4d
http://hdl.handle.net/11573/411529

Diatom structures templated by phase-separated fluids

Autor: Leonardo Lenoci, Philip J. Camp

Publikováno v: Lenoci, L & Camp, P J 2008, ' Diatom structures templated by phase-separated fluids ', Langmuir, vol. 24, no. 1, pp. 217-223 . https://doi.org/10.1021/la702278f

An experimentally motivated model is proposed for the formation of fluid-phase templates corresponding to the porous silica skeletons of diatoms, single-cell organisms found in marine and freshwater environments. It is shown that phase-separation pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10b800d5dacf46ecb0ed2950200ca89
https://hdl.handle.net/20.500.11820/dbb18628-fe95-4ef8-8eb9-1a35e4ed8303

Mathematical model of PAR1-mediated activation of human platelets

Autor: Heidi E. Hamm, Shalanda Satchell, Leonardo Lenoci, Matthew T. Duvernay, Emmanuele DiBenedetto

Publikováno v: Molecular BioSystems. 7:1129

Thrombin, one of the major proteases in the coagulation cascade, activates protease activated receptors 1 and 4 (PAR 1 and PAR4) to generate a network of intracellular signals that lead to stable platelet aggregation. Abnormal platelet activation cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980cbe729fbf25f826423e959bc0781c
https://doi.org/10.1039/c0mb00250j