Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Leonardo F. Ferreira"'
Autor:
Orlando Laitano, Jose Pindado, Isela Valera, Ray A. Spradlin, Kevin O. Murray, Katelyn R. Villani, Jamal M. Alzahrani, Terence E. Ryan, Philip A. Efron, Leonardo F. Ferreira, Elisabeth R. Barton, Thomas L. Clanton
Publikováno v:
Physiological Reports, Vol 9, Iss 14, Pp n/a-n/a (2021)
Abstract Sepsis induces a myopathy characterized by loss of muscle mass and weakness. Septic patients undergo prolonged periods of limb muscle disuse due to bed rest. The contribution of limb muscle disuse to the myopathy phenotype remains poorly des
Externí odkaz:
https://doaj.org/article/358f8f58bff24df79d0a3e6ac1268257
Autor:
Ravi A. Kumar, Trace Thome, Omar M. Sharaf, Terence E. Ryan, George J. Arnaoutakis, Eric I. Jeng, Leonardo F. Ferreira
Publikováno v:
Cells, Vol 11, Iss 15, p 2292 (2022)
Cardiomyocyte dysfunction in patients with end-stage heart failure with reduced ejection fraction (HFrEF) stems from mitochondrial dysfunction, which contributes to an energetic crisis. Mitochondrial dysfunction reportedly relates to increased marker
Externí odkaz:
https://doaj.org/article/76a5ae8dcb7b412b93e3b158932761fb
Autor:
Trace Thome, Ravi A. Kumar, Sarah K. Burke, Ram B. Khattri, Zachary R. Salyers, Rachel C. Kelley, Madeline D. Coleman, Demetra D. Christou, Russell T. Hepple, Salvatore T. Scali, Leonardo F. Ferreira, Terence E. Ryan
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Chronic kidney disease (CKD) causes progressive skeletal myopathy involving atrophy, weakness, and fatigue. Mitochondria have been thought to contribute to skeletal myopathy; however, the molecular mechanisms underlying muscle metabolism changes in C
Externí odkaz:
https://doaj.org/article/6eeb058807be4b4b9dc967c2b9ae67f9
Autor:
Orlando Laitano, Laila H. Sheikh, Alex J. Mattingly, Kevin O. Murray, Leonardo F. Ferreira, Thomas L. Clanton
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Hyperthermia and dehydration can occur during exercise in hot environments. Nevertheless, whether elevations in extracellular osmolality contributes to the increased skeletal muscle tension, sarcolemmal injury, and oxidative stress reported in warm c
Externí odkaz:
https://doaj.org/article/4b0181e89af54437832148cea7f6e345
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Externí odkaz:
https://doaj.org/article/8d4068c9cb734d66a20768b4fe8ecda0
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Externí odkaz:
https://doaj.org/article/54aa01e6a0754f47a32c9e6fb5006015
Autor:
Nicholas Balestrieri, Victoria Palzkill, Caroline Pass, Jianna Tan, Zachary R. Salyers, Chatick Moparthy, Ania Murillo, Kyoungrae Kim, Trace Thome, Qingping Yang, Kerri A. O’Malley, Scott A. Berceli, Feng Yue, Salvatore T. Scali, Leonardo F. Ferreira, Terence E. Ryan
Publikováno v:
bioRxiv
Chronic kidney disease (CKD) accelerates the development of atherosclerosis, decreases muscle function, and increases the risk of amputation or death in patients with peripheral artery disease (PAD). However, the cellular and physiological mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a3fe2fa3057e7bb4b5e9c60260eeba
https://europepmc.org/articles/PMC10245783/
https://europepmc.org/articles/PMC10245783/
Autor:
Coen A.C. Ottenheijm, Suzanne C. Brinson, Dongwoo Hahn, Shengyi Shen, Rachel C. Kelley, Eliza Balazic, Ravi A. Kumar, Leonardo F. Ferreira, Nuria Curbello-Bermudez, Andrea M. Noriega, Robbert van der Pijl, Terence E. Ryan, Lauren Betancourt, Derek R. Muscato
Publikováno v:
J Appl Physiol (1985)
Journal of Applied Physiology, 132(1), 106-125. American Physiological Society
Kelley, R C, Betancourt, L, Noriega, A M, Brinson, S C, Curbelo-Bermudez, N, Hahn, D, Kumar, R A, Balazic, E, Muscato, D R, Ryan, T E, van der Pijl, R J, Shen, S, Ottenheijm, C A C & Ferreira, L F 2022, ' Skeletal myopathy in a rat model of postmenopausal heart failure with preserved ejection fraction ', Journal of Applied Physiology, vol. 132, no. 1, pp. 106-125 . https://doi.org/10.1152/japplphysiol.00170.2021
Journal of Applied Physiology, 132(1), 106-125. American Physiological Society
Kelley, R C, Betancourt, L, Noriega, A M, Brinson, S C, Curbelo-Bermudez, N, Hahn, D, Kumar, R A, Balazic, E, Muscato, D R, Ryan, T E, van der Pijl, R J, Shen, S, Ottenheijm, C A C & Ferreira, L F 2022, ' Skeletal myopathy in a rat model of postmenopausal heart failure with preserved ejection fraction ', Journal of Applied Physiology, vol. 132, no. 1, pp. 106-125 . https://doi.org/10.1152/japplphysiol.00170.2021
Heart failure with preserved ejection fraction (HFpEF) accounts for ∼50% of all patients with heart failure and frequently affects postmenopausal women. The HFpEF condition is phenotype-specific, with skeletal myopathy that is crucial for disease d
Autor:
Guilherme Bresciani, Thomas Beaver, A. Daniel Martin, Robbert van der Pijl, Robert Mankowski, Christiaan Leeuwenburgh, Coen A.C. Ottenheijm, Tomas Martin, George Arnaoutakis, Shakeel Ahmed, Vinicius Mariani, Wei Xue, Barbara K. Smith, Leonardo F. Ferreira
RationaleMechanical ventilation rapidly induces slow and fast fiber contractile dysfunction in the human diaphragm, which could be attenuated by phrenic nerve stimulation. Here, we present data from a controlled trial of intraoperative phrenic stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed3bd379ec0d729e96f48201d75d36f2
https://doi.org/10.1101/2022.09.16.22279894
https://doi.org/10.1101/2022.09.16.22279894
Autor:
Ravi A. Kumar, Dongwoo Hahn, Rachel C. Kelley, Derek R. Muscato, Alex Shamoun, Nuria Curbelo-Bermudez, W. Greyson Butler, Svetlana Yegorova, Terence E. Ryan, Leonardo F. Ferreira
Patients with heart failure with reduced ejection fraction (HFrEF) experience diaphragm weakness that contributes to the primary disease symptoms of fatigue, dyspnea, and exercise intolerance. Weakness in the diaphragm is related to excessive product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea77cad9f392a29ec529284092cbe63
https://doi.org/10.1101/2022.05.27.493689
https://doi.org/10.1101/2022.05.27.493689