Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Leonardo Elia"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/a2687f58c60848b49a94d88e16e34ad7
Autor:
Jessica Mingardi, Luca La Via, Paolo Tornese, Giulia Carini, Kalevi Trontti, Mara Seguini, Daniela Tardito, Federica Bono, Chiara Fiorentini, Leonardo Elia, Iiris Hovatta, Maurizio Popoli, Laura Musazzi, Alessandro Barbon
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100381- (2021)
Converging clinical and preclinical evidence demonstrates that depressive phenotypes are associated with synaptic dysfunction and dendritic simplification in cortico-limbic glutamatergic areas. On the other hand, the rapid antidepressant effect of ac
Externí odkaz:
https://doaj.org/article/918673e220ed44929f78f6b4c70f4aa3
Autor:
Ignacio Fernando Hall, Montserrat Climent, Chiara Viviani Anselmi, Laura Papa, Vinicius Tragante, Luca Lambroia, Floriana Maria Farina, Marcus E Kleber, Winfried März, Carlo Biguori, Gianluigi Condorelli, Leonardo Elia
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp n/a-n/a (2021)
Abstract The role of single nucleotide polymorphisms (SNPs) in the etiopathogenesis of cardiovascular diseases is well known. The effect of SNPs on disease predisposition has been established not only for protein coding genes but also for genes encod
Externí odkaz:
https://doaj.org/article/3bb46620c005441294366419561c418f
Autor:
Marinos Kallikourdis, Elisa Martini, Pierluigi Carullo, Claudia Sardi, Giuliana Roselli, Carolina M. Greco, Debora Vignali, Federica Riva, Anne Marie Ormbostad Berre, Tomas O. Stølen, Andrea Fumero, Giuseppe Faggian, Elisa Di Pasquale, Leonardo Elia, Cristiano Rumio, Daniele Catalucci, Roberto Papait, Gianluigi Condorelli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Abatacept is an FDA-approved drug used for treatment of rheumatoid arthritis. Here the authors show that abatacept reduces cardiomyocyte death in a mouse model of heart failure by inhibiting activation and heart infiltration of T cells and macrophage
Externí odkaz:
https://doaj.org/article/73c739f75c0e45a385907278d0b7888b
Autor:
Leonardo Elia, Manuela Quintavalle
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
Epigenetics refers to heritable mechanisms able to modulate gene expression that do not involve alteration of the genomic DNA sequence. Classically, mechanisms such as DNA methylation and histone modifications were part of this classification. Today,
Externí odkaz:
https://doaj.org/article/48d9b9fa137b4164ace68989b86b4ade
Publikováno v:
BMJ case reports. 15(12)
Costello syndrome (CS) is a rare genetic syndrome affecting multiple organs, generally caused by mutations of theHRASgene, belonging to theRAS/MAPKgenes family.A male patient with CS developed a painful pulsatile mass on the lateral side of the wrist
Publikováno v:
British Journal of Pharmacology. 179:3430-3451
Idiopathic pulmonary fibrosis is a devastating disease with multiple contributing factors. Insulin-like growth factor 1 receptor (IGF1R), with a reciprocal function to aryl hydrocarbon receptor (AhR), is involved in airway inflammation. The exact rel
Publikováno v:
Epigenetic Epidemiology ISBN: 9783030944742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f467c72dfe0fd1abdc081fe0eed2b068
https://doi.org/10.1007/978-3-030-94475-9_20
https://doi.org/10.1007/978-3-030-94475-9_20
Autor:
Floriana Maria Farina, Simone Serio, Ignacio Fernando Hall, Stefania Zani, Giada Andrea Cassanmagnago, Montserrat Climent, Efrem Civilini, Gianluigi Condorelli, Manuela Quintavalle, Leonardo Elia
AimsHistone H3 dimethylation at lysine 79 is a key epigenetic mark uniquely induced by methyltransferase disruptor of telomeric silencing 1-like (DOT1L). We aimed to determine whether DOT1L modulates vascular smooth muscle cell (VSMC) phenotype and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc196b600501aaba382d034deb4b08f
http://hdl.handle.net/11379/554448
http://hdl.handle.net/11379/554448
Autor:
Laura Papa, Vinicius Tragante, Winfried März, Carlo Biguori, Montserrat Climent, Gianluigi Condorelli, Marcus E. Kleber, Luca Lambroia, Leonardo Elia, Chiara Viviani Anselmi, Floriana Maria Farina, Ignacio Fernando Hall
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine
The role of single nucleotide polymorphisms (SNPs) in the etiopathogenesis of cardiovascular diseases is well known. The effect of SNPs on disease predisposition has been established not only for protein coding genes but also for genes encoding micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6066eb4a08fe7fa77073eb1da9538ad3
https://zenodo.org/record/5747565
https://zenodo.org/record/5747565