Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Leonardo Astolfi Rosado"'
1
Akademický článek
The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress
Autor: Melanie Hillion, Marcel Imber, Brandán Pedre, Jörg Bernhardt, Malek Saleh, Vu Van Loi, Sandra Maaß, Dörte Becher, Leonardo Astolfi Rosado, Lorenz Adrian, Christoph Weise, Rüdiger Hell, Markus Wirtz, Joris Messens, Haike Antelmann
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes and functions in post-translational thiol-modification by protein S-mycothiolation as emerging thiol-protection and redox-regulatory mechanism. Here, we have used
Externí odkaz: https://doaj.org/article/21e9ed05d56247fb863ba4096fc668dd
Zobrazit plný text záznamu
2
Akademický článek
Biochemical characterization of uracil phosphoribosyltransferase from Mycobacterium tuberculosis.
Autor: Anne Drumond Villela, Rodrigo Gay Ducati, Leonardo Astolfi Rosado, Carlos Junior Bloch, Maura Vianna Prates, Danieli Cristina Gonçalves, Carlos Henrique Inacio Ramos, Luiz Augusto Basso, Diogenes Santiago Santos
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56445 (2013)
Uracil phosphoribosyltransferase (UPRT) catalyzes the conversion of uracil and 5-phosphoribosyl-α-1-pyrophosphate (PRPP) to uridine 5'-monophosphate (UMP) and pyrophosphate (PP(i)). UPRT plays an important role in the pyrimidine salvage pathway sinc
Externí odkaz: https://doaj.org/article/1016413b77c342b193a7a517ac53c811
Zobrazit plný text záznamu
3
Akademický článek
The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.
Autor: Leonardo Astolfi Rosado, Igor Bordin Vasconcelos, Mário Sérgio Palma, Vincent Frappier, Rafael Josef Najmanovich, Diógenes Santiago Santos, Luiz Augusto Basso
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e61918 (2013)
Tuberculosis remains as one of the main cause of mortality worldwide due to a single infectious agent, Mycobacterium tuberculosis. The aroK-encoded M. tuberculosis Shikimate Kinase (MtSK), shown to be essential for survival of bacilli, catalyzes the
Externí odkaz: https://doaj.org/article/4b60fdc1e6ee43cf83713bfcc13c10b7
Zobrazit plný text záznamu
5
Protein promiscuity in H2O2 signaling
Autor: Leonardo Astolfi Rosado, Brandán Pedre, Aleksandra Lewandowska, Jingjing Huang, Joris Messens, Nandita Bodra, Daria Ezeriņa, Frank Van Breusegem, Barbara De Smet, Maria-Armineh Tossounian, David Young
Publikováno v: ANTIOXIDANTS & REDOX SIGNALING
Significance: Decrypting the cellular response to oxidative stress relies on a comprehensive understanding of the redox signaling pathways stimulated under oxidizing conditions. Redox signaling events can be divided into upstream sensing of oxidants,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f186ff7179dbe8c4cea85a0bffd4a0d0
https://biblio.vub.ac.be/vubir/protein-promiscuity-in-h2o2-signaling(8a8ec61a-30dc-4a81-8c45-ccfc5ae10f69).html
Zobrazit plný text záznamu
7
Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2 sensing
Autor: Brandán Pedre, David Young, Daniel Charlier, Álvaro Mourenza, Leonardo Astolfi Rosado, Laura Marcos-Pascual, Khadija Wahni, Edo Martens, Alfonso G. de la Rubia, Vsevolod V. Belousov, Luis M. Mateos, Joris Messens
Publikováno v: 'Proceedings of the National Academy of Sciences of the USA ', vol: 115, pages: E11623-E11632 (2018)
Hydrogen peroxide (H 2 O 2 ) is a strong oxidant capable of oxidizing cysteinyl thiolates, yet only a few cysteine-containing proteins have exceptional reactivity toward H 2 O 2 . One such example is the prokaryotic transcription factor OxyR, which c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3003ad374e4802539dc2472b3969fb
https://doi.org/10.1073/pnas.1807954115
Zobrazit plný text záznamu
8
Structural snapshots of OxyR reveal the peroxidatic mechanism of H
Autor: Brandán, Pedre, David, Young, Daniel, Charlier, Álvaro, Mourenza, Leonardo Astolfi, Rosado, Laura, Marcos-Pascual, Khadija, Wahni, Edo, Martens, Alfonso, G de la Rubia, Vsevolod V, Belousov, Luis M, Mateos, Joris, Messens
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Significance The bacterial transcription factor OxyR is a model example of a highly sensitive and specific hydrogen peroxide (H2O2) sensor. H2O2 reduction by its active-site cysteine triggers protein structural changes leading to an increased transcr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a984b32dd164598f132fef524ed63a5f
https://pubmed.ncbi.nlm.nih.gov/30463959
Zobrazit plný text záznamu
10
Protein Promiscuity in H
Autor: David, Young, Brandan, Pedre, Daria, Ezeriņa, Barbara, De Smet, Aleksandra, Lewandowska, Maria-Armineh, Tossounian, Nandita, Bodra, Jingjing, Huang, Leonardo, Astolfi Rosado, Frank, Van Breusegem, Joris, Messens
Publikováno v: Antioxidantsredox signaling. 30(10)
Decrypting the cellular response to oxidative stress relies on a comprehensive understanding of the redox signaling pathways stimulated under oxidizing conditions. Redox signaling events can be divided into upstream sensing of oxidants, midstream red
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac2a2116fb84d2366b4ed559555a1e24
https://pubmed.ncbi.nlm.nih.gov/29635930
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje