Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Leonardo A. Gómez"'
Autor:
Raúl E. Molina, Alberto Osorio, Manuel Flores-Concha, Leonardo A. Gómez, Ilse Alvarado, Italo Ferrari, Angel Oñate
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe development of effective vaccines against Brucella abortus is critical due to its significant impact on human and animal health. The objective of this study was to design and evaluate in silico and in vivo a multivalent vaccine based
Externí odkaz:
https://doaj.org/article/f6e1d547e6a1412ea2392d4da9948698
Autor:
Manuel Flores-Concha, Leonardo A. Gómez, Rodrigo Soto-Shara, Raúl E. Molina, Roberto F. Coloma-Rivero, David A. Montero, Ítalo Ferrari, Ángel Oñate
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe lncRNAs (long non-coding RNAs) are the most diverse group of non-coding RNAs and are involved in most biological processes including the immune response. While some of them have been recognized for their influence on the regulation of
Externí odkaz:
https://doaj.org/article/2f8b344a912e42a58bbd30f787bdeac0
Autor:
Esther M. Campo-Bautista, Cristhian Rubio-Ramos, Leonardo A. Gómez-Cortés, Paola Cruz-Tapias, David R. Rodríguez-Lima
Publikováno v:
Revista Colombiana de Cardiología, Vol 30, Iss 4 (2023)
Introducción: La fibrilación auricular posoperatoria en el contexto de cirugía cardíaca es una complicación frecuente y genera un incremento del riesgo de embolia sistémica; la estrategia de anticoagulación en pacientes con duración de la arr
Externí odkaz:
https://doaj.org/article/e7e03bd6915b4d4db93c4db7f52f31af
Autor:
David A. Montero, Roberto M. Vidal, Juliana Velasco, Sergio George, Yalda Lucero, Leonardo A. Gómez, Leandro J. Carreño, Richard García-Betancourt, Miguel O’Ryan
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Vibrio cholerae is the causative agent of cholera, a highly contagious diarrheal disease affecting millions worldwide each year. Cholera is a major public health problem, primarily in countries with poor sanitary conditions and regions affected by na
Externí odkaz:
https://doaj.org/article/73bceb8bd51f4eef8de8fcb1cc572741
Autor:
Leonardo A. Gómez, Raúl E. Molina, Rodrigo I. Soto, Manuel R. Flores, Roberto F. Coloma-Rivero, David A. Montero, Ángel A. Oñate
Publikováno v:
Toxins, Vol 15, Iss 9, p 536 (2023)
Toxin/antitoxin (TA) systems have been scarcely studied in Brucella abortus, the causative agent of brucellosis, which is one of the most prevalent zoonotic diseases worldwide. In this study, the roles of a putative type II TA system composed by a Zi
Externí odkaz:
https://doaj.org/article/a5e0079978d54345894c20c8aa3e9333
Autor:
Leonardo A. Gómez, Francisco I. Alvarez, Raúl E. Molina, Rodrigo Soto-Shara, Carla Daza-Castro, Manuel R. Flores, Yrvin León, Angel A. Oñate
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Brucella abortus is a pathogen that survives in macrophages. Several virulence factors participate in this process, including the open reading frame (ORF) BAB1_0270 codifying for a zinc-dependent metalloproteinase (ZnMP). Here, its contribution in th
Externí odkaz:
https://doaj.org/article/eaeb53d1c10041e8826f6592bc74532a
Autor:
Yrvin León, Lionel Zapata, Raúl E. Molina, Gaj Okanovič, Leonardo A. Gómez, Carla Daza-Castro, Manuel Flores-Concha, José L. Reyes, Angel A. Oñate
Publikováno v:
Vaccines, Vol 8, Iss 4, p 563 (2020)
Shigellosis is a diarrheal disease and the World Health Organization prompts the development of a vaccine against Shigella flexneri. The autotransporters SigA, Pic and Sap are conserved among Shigella spp. We previously designed an in silico vaccine
Externí odkaz:
https://doaj.org/article/d18510cfb11f4c2caa8ed6bc9b8eff54
Autor:
Daniela Rios Ramirez, Karen, Botero Ñañez, Katerine, Leonardo Gonzalez Gomez, Cristian, Thiago Andrade Moreira, Ícaro
Publikováno v:
In Environmental Research 15 November 2024 261
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Publikováno v:
Revista Finlay, Vol 12, Iss 1, Pp 106-116 (2022)
Sars-Cov-2, is a virus belonging to the coronaviridae family, responsible for the pandemic that has been plaguing the world since December 2019, which produces the infectious disease called COVID-19. This disease is expressed in more than half of the
Externí odkaz:
https://doaj.org/article/7555d67cb8a54b27826166201c367e9c