Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Leonard von Eckardstein"'
Autor:
Lida Rostock, Ronja Driller, Stefan Grätz, Dennis Kerwat, Leonard von Eckardstein, Daniel Petras, Maria Kunert, Claudia Alings, Franz-Josef Schmitt, Thomas Friedrich, Markus C. Wahl, Bernhard Loll, Andi Mainz, Roderich D. Süssmuth
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The potent antibacterial compound albicidin is synthesized by the plant-pathogenic bacterium Xanthomonas albilineans. Here the authors employ a multidisciplinary approach and provide structural and mechanistic insights into how the drug-binding prote
Externí odkaz:
https://doaj.org/article/ef5cd126b6d942939a1a01e88363268b
Autor:
Adelina Duka, Panagiotis Fotakis, Dimitra Georgiadou, Andreas Kateifides, Kalliopi Tzavlaki, Leonard von Eckardstein, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 107-115 (2013)
The objective of this study was to establish the role of apoA-IV, ABCA1, and LCAT in the biogenesis of apoA-IV-containing HDL (HDL-A-IV) using different mouse models. Adenovirus-mediated gene transfer of apoA-IV in apoA-I−/− mice did not change p
Externí odkaz:
https://doaj.org/article/10135362fd5d4dbdb4085ccc23cc9a45
Autor:
Lieby Zborovsky, John B. Weston, Frank Otto Gombert, Leonard von Eckardstein, Arseni Kostenko, Roderich D. Süssmuth, Leonardo Kleebauer, Maria Seidel
Publikováno v:
Chemical Science
The worrisome development and spread of multidrug-resistant bacteria demands new antibacterial agents with strong bioactivities particularly against Gram-negative bacteria. Albicidins were recently structurally characterized as highly active antibact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdbe69bf24b4dde0bcab10ed27a9c94
https://pubmed.ncbi.nlm.nih.gov/34881013
https://pubmed.ncbi.nlm.nih.gov/34881013
Autor:
Ho Ryu, Leonard von Eckardstein, Roderich D. Süssmuth, Jinhoon Jeong, Bianca Schmid, Karlijn Keijzer, Mu-Hyun Baik, Todor Baramov
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(28)
The E. coli siderophore enterobactin, the strongest FeIII chelator known to date, forms hexacoordinate complexes with SiIV , GeIV , and TiIV . Synthetic protocols have been developed to prepare non-symmetric enterobactin analogues with varying dentic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1dc0ac38e934738d2457c27e3435c7
https://pubmed.ncbi.nlm.nih.gov/30816591
https://pubmed.ncbi.nlm.nih.gov/30816591
Autor:
Dennis Kerwat, Siamak Semsary, Maria Seidel, Stefan Grätz, Roderich D. Süssmuth, Maria Kunert, Leonard von Eckardstein, John B. Weston, Julian Kretz
Publikováno v:
ChemMedChem. 11:1499-1502
To investigate the pharmacophore regions of the antibiotic albicidin, derivatives with variations on the central amino acid were synthesized. Charged as well as uncharged residues were chosen to explore the influence of charge, chirality, and steric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362c47eb71a542df8881057f358ab52c
https://doi.org/10.1002/cmdc.201600163
https://doi.org/10.1002/cmdc.201600163
Autor:
Dennis Kerwat, Maria Seidel, Tam Dang, Pieter C. Dorrestein, Roderich D. Süssmuth, Souhir Sabri, Daniel Petras, Leonard von Eckardstein, Stefan Grätz, Alexander Pesic, John B. Weston, Monique Royer, Stéphane Cociancich
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, pp.1-6. ⟨10.1002/chem.201704074⟩
Chemistry-A European Journal 61 (23), 15316-15321. (2017)
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (61), pp.1-6. ⟨10.1002/chem.201704074⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, pp.1-6. ⟨10.1002/chem.201704074⟩
Chemistry-A European Journal 61 (23), 15316-15321. (2017)
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (61), pp.1-6. ⟨10.1002/chem.201704074⟩
Natural products represent an important source of potential novel antimicrobial drug leads. Low production by microorganisms in cell culture often delays the structural elucidation or even prevents a timely discovery. Starting from the anti-Gram-nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebff5f2a9ba1b7d5e05296ceabcc5b34
https://hal.archives-ouvertes.fr/hal-01608574
https://hal.archives-ouvertes.fr/hal-01608574
Autor:
Ho Ryu, Bianca Schmid, Mu-Hyun Baik, Jinhoon Jeong, Roderich D. Süssmuth, Todor Baramov, Karlijn Keijzer, Leonard von Eckardstein
Publikováno v:
Chemistry – A European Journal. 25:6851-6851
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a820732e1115bd2a104d44a8bb52e5c5
https://doi.org/10.1002/chem.201901473
https://doi.org/10.1002/chem.201901473
Autor:
Daniel Petras, Mélanie Marguerettaz, Siamak Semsary, Alexander Pesic, Leonard von Eckardstein, Benjamin-F Hempel, Monique Royer, Julie Arasté, Roderich D. Süssmuth, Stéphane Cociancich, Dennis Kerwat
Publikováno v:
ACS Chemical Biology
Albicidin is a potent antibiotic and phytotoxin produced by Xanthomonas albilineans which targets the plant and bacterial DNA gyrase. We now report on a new albicidin derivative which is carbamoylated at the N-terminal coumaric acid by the action of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e457466cb4a3c72e2ebc6c280a43f7
http://agritrop.cirad.fr/585591/
http://agritrop.cirad.fr/585591/