Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Leonard V Sacks"'
Autor:
Ashok Krishna, Tesfalem Zere, Sabyasachy Mistry, Omnia Ismaiel, Heather Stone, Leonard V. Sacks, James L. Weaver
Publikováno v:
Antibiotics, Vol 11, Iss 12, p 1705 (2022)
Objective: Employ the hollow fiber infection model (HFIM) to study sequential antibiotic administration (ampicillin, ciprofloxacin and fosfomycin) using human pharmacokinetic profiles to measure changes in the rate of antibiotic resistance developmen
Externí odkaz:
https://doaj.org/article/e881764f212b401f8897b93ad895b477
Publikováno v:
PLoS Medicine, Vol 4, Iss 11, p e292 (2007)
Externí odkaz:
https://doaj.org/article/0bfa7b256bad41dba11a799f63dfa8d8
Autor:
Pei Wang, Veena Misra, Ian Ferguson, John J. Mastrototaro, Michelle Crouthamel, Brian M. Bot, Linda A. Malek, John D. Hixson, Glen de Vries, Leonard V. Sacks, Aydogan Ozcan, Pamela C. Baker, Bernard H. Munos
Publikováno v:
Annals of the New York Academy of Sciences. 1375:3-18
Mobile technology has become a ubiquitous part of everyday life, and the practical utility of mobile devices for improving human health is only now being realized. Wireless medical sensors, or mobile biosensors, are one such technology that is allowi
Autor:
Rachel E. Behrman, Leonard V. Sacks
Publikováno v:
Future Medicinal Chemistry. 1:749-756
Despite efficacious drugs for treatment, TB continues to affect enormous numbers of patients throughout the world. Failure to control TB may be related to the biological characteristics of Mycobacterium tuberculosis, the nature of susceptible hosts o
Autor:
Leonard V. Sacks, Rachel E. Behrman
Publikováno v:
Tuberculosis. 88:S93-S100
Simplifying and shortening treatment for drug-sensitive tuberculosis and providing new treatment options for drug-resistant tuberculosis constitute two principal goals in the development of novel drugs for tuberculosis. Demonstration of clinical effi
Autor:
Leonard V. Sacks, Noel Southall, Mili Duggal, Rosemary Tiernan, Timothy Sheils, Heather Stone
Publikováno v:
Open Forum Infectious Diseases
Background Repurposing approved products has proven a critical strategy to serve unmet medical needs. Historically, 40% of drugs approved for treatment of tropical diseases were repurposed, including albendazole for echinococcosis and neurocysticerco
Publikováno v:
PLoS Medicine, Vol 4, Iss 11, p e292 (2007)
The time is now right for randomized trials of MDR-TB, say the authors, as the expansion of MDR-TB programs provides the setting in which trials can be implemented.
Autor:
Stephina N Nyoka, Timothy R. Sterling, Christopher L. Karp, Richard E. Chaisson, Leonard V. Sacks, Liesl Page-Shipp, Helba Bredell, Thomas C. Quinn, Stella Pendle, Desmond J. Martin, Lynn Morris
Publikováno v:
The Journal of infectious diseases. 187(12)
During 6 months of treatment, we measured human immunodeficiency virus (HIV)-1 virus loads, CD4 T cell counts, and immune activation markers, in 111 HIV-1-infected patients with active tuberculosis (TB). The median virus load (baseline, 5.58 log(10)
Autor:
Martin A. R. Yuille, Friedrich G. Petermann, Leonard V. Sacks, Cheryl K. Lapham, Russell H. Tomar, Patricia A. John
Publikováno v:
The Journal of infectious diseases. 164(3)
Natural killer (NK) activity in peripheral blood mononuclear cells is augmented by products released by two different strains of streptococci. This property is due at least in part to an erythrogenic toxin (ET). A preparation of physiologically activ
Autor:
Leonard V. Sacks
Publikováno v:
Clinical Infectious Diseases. 33:267-267