Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Leonard T. Skeggs"'
Autor:
Leonard T. Skeggs, Harry Hochstrasser
Publikováno v:
Annals of the New York Academy of Sciences. 102:144-160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c7918ee0a586e8bd8902aaaf1fbfeb6
https://doi.org/10.1111/j.1749-6632.1962.tb13634.x
https://doi.org/10.1111/j.1749-6632.1962.tb13634.x
Autor:
Leonard T. Skeggs
Publikováno v:
Clinical Chemistry. 46:1425-1436
I am a relic of the last century, born in 1918, the last year of the first World War. At that time, there was no radio, no television, no commercial air travel. There was no welfare, no social security, no Medicare, and only the rich paid income taxe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38acfba76fed4ff43a978206aa3e682
https://doi.org/10.1093/clinchem/46.9.1425
https://doi.org/10.1093/clinchem/46.9.1425
Autor:
Leonard T. Skeggs
Publikováno v:
American Journal of Hypertension. 4:578S-583S
It is known that the renin angiotension system as it is usually understood is not the mediator of experimental one-kidney, one-clip (1K,1C) hypertension in animals. There is also ample evidence that the blood pressure of dogs and rabbits with this fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a726970f7f0d033682d7480f27fc2ff6
https://doi.org/10.1093/ajh/4.10.578s
https://doi.org/10.1093/ajh/4.10.578s
Autor:
Leonard T. Skeggs
Publikováno v:
American Journal of Hypertension. 4:521S-522S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49e712fd365ed457c2cd69b237c0d4f8
https://doi.org/10.1093/ajh/4.10.521s
https://doi.org/10.1093/ajh/4.10.521s
Publikováno v:
Hypertension. 6:374-382
Spleen cells from mice immunized with partially purified hog kidney renin were fused with mouse myeloma cells to produce a stable monoclonal hybridoma cell line that synthesizes an antibody against renin. A single monoclonal antibody was chosen for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b8ad0bcd8ff1b1dd9ee64895310d97
https://doi.org/10.1161/01.hyp.6.3.374
https://doi.org/10.1161/01.hyp.6.3.374
Autor:
Leonard T. Skeggs
Publikováno v:
Hospital Practice. 9:145-154
In the attempt to work out the steps and identify the participants in the renin/angiotensin system, investigators have been confronted with an amazingly complex biochemical jigsaw puzzle in which the need has been to fit together various hormones, en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe27ccbdf94a1f37ae1b34f553461c5b
https://doi.org/10.1080/21548331.1974.11707971
https://doi.org/10.1080/21548331.1974.11707971
Publikováno v:
Circulation Research. 34:824-827
Two dipeptides, phenylalanylarginine (Phe-Arg) and serylproline (Ser-Pro), are released sequentially from bradykinin by angiotensin-converting enzyme purified from hog lungs; chloride increases the rate of release of both dipeptides. Using an automat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad1b7a6af4c7d6f59dfa831ce5c8782
https://doi.org/10.1161/01.res.34.6.824
https://doi.org/10.1161/01.res.34.6.824
Publikováno v:
The American Journal of Medicine. 60:737-748
The renin-angiotensin system has an important role in maintaining elevated blood pressure levels in certain forms of experimental and human hypertension. Renin, an enzyme produced by the juxtaglomerular cells of the kidney, acts on a protein substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a39cedc4f83f60eb8b2130ae90bc64d
https://doi.org/10.1016/0002-9343(76)90888-3
https://doi.org/10.1016/0002-9343(76)90888-3
Publikováno v:
Analytical Biochemistry. 87:11-18
Renin substrate, angiotensinogen, has been purified from human plasma by methods which permit the processing of large amounts of outdated bank blood. The purified protein is homogeneous by disc gel electrophoresis at pH 9.5. The specific activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00ca8a3959a3266590b804d50359bce
https://doi.org/10.1016/0003-2697(78)90563-8
https://doi.org/10.1016/0003-2697(78)90563-8
Publikováno v:
Circulation Research. 37:715-724
An investigation into the mechanism that sustains the blood pressure in chronic one-kidney hypertension in rabbits was made using passive and active immunization with hog kidney extracts containing renin and with angiotensin antagonists. Seven hypert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7f8fd155aec8b645f8a9f8215d3700
https://doi.org/10.1161/01.res.37.6.715
https://doi.org/10.1161/01.res.37.6.715