Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Leonard Rosenberg"'
Autor:
Antoine N. Saliba, Scott H. Kaufmann, Eytan M. Stein, Prapti A. Patel, Maria R. Baer, Wendy Stock, Michael Deininger, William Blum, Gary J. Schiller, Rebecca L. Olin, Mark R. Litzow, Tara L. Lin, Brian J. Ball, Michael M. Boyiadzis, Elie Traer, Olatoyosi Odenike, Martha L. Arellano, Alison Walker, Vu H. Duong, Tibor Kovacsovics, Robert H. Collins, Abigail B. Shoben, Nyla A. Heerema, Matthew C. Foster, Kevin L. Peterson, Paula A. Schneider, Molly Martycz, Theophilus J. Gana, Leonard Rosenberg, Sonja Marcus, Ashley O. Yocum, Timothy Chen, Mona Stefanos, Alice S. Mims, Uma Borate, Amy Burd, Brian J. Druker, Ross L. Levine, John C. Byrd, James M. Foran
Publikováno v:
Blood Advances. 7:2360-2363
Autor:
Eytan Stein, Sheng F Cai, Ying Huang, Andrew Dunbar, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William G. Blum, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti A. Patel, Matthew C. Foster, Michael M. Boyiadzis, Robert H. Collins, Jordan Chervin, Abigail B. Shoben, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Timothy Chen, Ashley O. Yocum, Franchesca Druggan, Sonja Marcus, Mona Stefanos, Molly Martycz, Brian J. Druker, Alice S. Mims, Uma Borate, Amy Burd, John C. Byrd, Ross L. Levine
Publikováno v:
Blood. 140:2016-2019
Autor:
Joshua F. Zeidner, Matthew C. Foster, Mary Johnson, Ying Huang, Ronan T. Swords, Eytan Stein, James M. Foran, Maria R. Baer, Wendy Stock, Yazan F. Madanat, Tibor Kovacsovics, Rebecca L. Olin, William G. Blum, Gary J. Schiller, Tara L. Lin, Robert L. Redner, Zeina Al-Mansour, Emily K Curran, Nyla A. Heerema, Molly Martycz, Leonard Rosenberg, Sonja Marcus, Ashley O. Yocum, Timothy Chen, Mona Stefanos, Franchesca Druggan, Amy Burd, Ross L. Levine, Brian J. Druker, Uma Borate, John C. Byrd, Alice S. Mims
Publikováno v:
Blood. 140:9070-9073
Autor:
Uma Borate, Rui Li, Ying Huang, Ronan T. Swords, Elie Traer, Eytan Stein, James M. Foran, Maria R. Baer, Vu H. Duong, Wendy Stock, Olatoyosi Odenike, Prapti Patel, Robert H. Collins, Yazan F. Madanat, Tibor Kovacsovics, Michael W. Deininger, Catherine Smith, Rebecca L. Olin, Martha L. Arellano, William G. Blum, Gary J. Schiller, Tara L. Lin, Matthew C. Foster, Michael M. Boyiadzis, Robert L. Redner, Zeina Al-Mansour, Emily K Curran, Nyla A. Heerema, Theophilus J Gana, Molly Martycz, Leonard Rosenberg, Sonja Marcus, Ashley O. Yocum, Timothy Chen, Mona Stefanos, Franchesca Druggan, Amy Burd, Ross L. Levine, Brian J. Druker, John C. Byrd, Alice S. Mims
Publikováno v:
Blood. 140:6200-6203
Autor:
Vu H. Duong, Amy S. Ruppert, Alice S. Mims, Uma Borate, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti A. Patel, Matthew C. Foster, Robert L. Redner, Zeina Al‐Mansour, Christopher R. Cogle, Ronan T. Swords, Robert H. Collins, Jo‐Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley O. Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J. Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Michael M. Boyiadzis
Publikováno v:
Cancer.
Autor:
Jordan Chervin, Ross L. Levine, Tara L. Lin, Ying Huang, William Blum, Sonja Marcus, Tibor Kovacsovics, Ashley O. Yocum, Franchesca Druggan, Gary J. Schiller, Brian J. Druker, Mona Stefanos, Uma Borate, Matthew C. Foster, Mark R. Litzow, John C. Byrd, Nyla A. Heerema, Robert H. Collins, Abigail B. Shoben, Wendy Stock, Leonard Rosenberg, Amy Burd, Michael Boyiadzis, James M. Foran, Rebecca L. Olin, Jo-Anne Vergilio, Prapti A. Patel, Maria R. Baer, Timothy L. Chen, Eytan M. Stein, Alice S. Mims
Publikováno v:
Blood. 136:27-30
Background: ENA is an oral, selective inhibitor of IDH2 approved for the treatment (Tx) of patients (pts) with relapsed/refractory IDH2 mutated (IDH2m) AML. Here we report the results of a Phase 2 expansion and Phase 1b of the Beat AML Master Trial P
Autor:
Nyla A. Heerema, Ashley Owen Yocum, Timothy L. Chen, Eric Allan Severson, Leonard Rosenberg, Michael Boyiadzis, Martha Arellano, Brian J. Druker, Rebecca L. Olin, Tibor Kovacsovics, Robert H. Collins, Amy Burd, Abigail B. Shoben, Maria R. Baer, Olatoyosi Odenike, Sonja Marcus, Mark R. Litzow, Elie Traer, Michael W. Deininger, Uma Borate, Tara L. Lin, Alice S. Mims, Molly Rae Miller, William Blum, John C. Byrd, Gary J. Schiller, Vu H. Duong, Jo Anne Vergilio, Mona Stefanos, Prapti A. Patel, Christine Vietz, James M. Foran, Matthew C. Foster, Tim Brennan, Amy S. Ruppert, Wendy Stock, Brian Ball, Ross L. Levine, Alison Walker, Eytan M. Stein
Publikováno v:
Nature medicine, vol 26, iss 12
Nat Med
Nat Med
Acute myeloid leukemia (AML) is the most common diagnosed leukemia. In older adults, AML confers an adverse outcome1,2. AML originates from a dominant mutation, then acquires collaborative transformative mutations leading to myeloid transformation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27387b90bfe2c4dba58c8d43efb1eaeb
https://escholarship.org/uc/item/8n11r5ct
https://escholarship.org/uc/item/8n11r5ct
Autor:
Amy Burd, Matthew C. Foster, William Blum, James M. Foran, Sonja Marcus, Tibor Kovacsovics, Zeina Al-Mansour, Maria R. Baer, Robert H. Collins, Theophilus J Gana, Robert L. Redner, Franchesca Druggan, John C. Byrd, Amy S. Ruppert, Brian J. Druker, Leonard Rosenberg, Prapti A. Patel, Ronan Swords, Gary J. Schiller, Martha Arellano, Tara L. Lin, Wendy Stock, Abigail B. Shoben, Timothy L. Chen, Christopher R. Cogle, Mona Stefanos, Ashley O. Yocum, Alice S. Mims, Uma Borate, Eytan M. Stein, Ross L. Levine, Rebecca L. Olin, Nyla A. Heerema, Jo-Anne Vergilio, Mark R. Litzow, Michael Boyiadzis
Publikováno v:
Blood. 138:875-875
Background: IVO is an oral potent inhibitor of mutated IDH1 (IDH1m) enzyme, recently approved for the treatment (Tx) of ND adult patients (pts) with IDH1m AML ≥75 years old or with comorbidities precluding use of intensive induction chemotherapy, a
Autor:
Alice S. Mims, Prapti A. Patel, Martha Arellano, Ronan Swords, Maria R. Baer, Nyla A. Heerema, William Blum, Matthew C. Foster, Tibor Kovacsovics, Amy Burd, Christopher R. Cogle, Mona Stefanos, Brian J. Druker, Timothy L. Chen, Gary J. Schiller, Uma Borate, Eytan M. Stein, Ross L. Levine, Franchesca Druggan, James M. Foran, Ashley O. Yocum, Robert L. Redner, Robert H. Collins, Jo-Anne Vergilio, Elie Traer, Ying Huang, Rebecca L. Olin, Tara L. Lin, Mark R. Litzow, Zeina Al-Mansour, Abigail B. Shoben, Sonja Marcus, Theophilus J Gana, John C. Byrd, Wendy Stock, Michael Boyiadzis, Leonard Rosenberg
Publikováno v:
Blood. 138:1277-1277
Background: GILT is an oral potent selective FLT3 kinase inhibitor approved for marketing for the treatment (Tx) of patients (pts) with relapsed/refractory FLT3 mutated (FLT3m) AML but efficacy in older ND FLT3m AML pts is unknown. Furthermore, FLT3m
Autor:
Matthew C. Foster, Alice S. Mims, Uma Borate, Abigail B. Shoben, Ashley O. Yocum, Wendy Stock, Prapti A. Patel, Timothy L. Chen, Ronan Swords, Maria R. Baer, Tara L. Lin, Gary J. Schiller, Amy Burd, Martha Arellano, James M. Foran, Sonja Marcus, Brian J. Druker, William Blum, Michael Boyiadzis, Ross L. Levine, Theophilus J Gana, Zeina Al-Mansour, Vu H. Duong, Franchesca Druggan, John C. Byrd, Robert H. Collins, Leonard Rosenberg, Tibor Kovacsovics, Mona Stefanos, Robert L. Redner, Amy S. Ruppert, Mark R. Litzow, Rebecca L. Olin, Nyla A. Heerema, Christopher R. Cogle, Jo-Anne Vergilio, Eytan M. Stein
Publikováno v:
Blood. 138:1279-1279
Background: In vitro studies and emerging clinical data suggest that inhibition of spleen tyrosine kinase may have an antileukemic effect in human AML. Pts with AML and TP53 mutations (TP53m) are commonly associated with older age (≥60 years) and c