Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Leonard Oppenheimer"'
Autor:
Torsten Westermeier, Juergen Weber, Leonard Oppenheimer, Kenneth Todd Moore, Christopher C. Nessel, Andrea Nadel, Xiang Sun, Sanjay Jalota, Nancy Cook-Bruns, Gary Peters, Paul Burton, Guohua Pan, Frank Misselwitz, Elisabeth Perzborn, Peter M DiBattiste, Troy C. Sarich, Lloyd Haskell, Scott D. Berkowitz, Anthonie W. A. Lensing, Dagmar Kubitza
Publikováno v:
Annals of the New York Academy of Sciences. 1291:42-55
The development of rivaroxaban (XARELTO®) is an important new medical advance in the field of oral anticoagulation. Thrombosis-mediated conditions constitute a major burden for patients, healthcare systems, and society. For more than 60 years, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ebfe774abb21c0c1d6343af1113aa95
https://doi.org/10.1111/nyas.12136
https://doi.org/10.1111/nyas.12136
Autor:
Michael Lee, Hong Tian, Roderick J. A. Little, Alexei N. Plotnikov, Janet Wittes, Leonard Oppenheimer, Eun Young Suh, Troy C. Sarich, C. Michael Gibson, Surya Mohanty, Xiang Sun, Paul Burton, Nancy Cook-Bruns, Julia Wang
Publikováno v:
Clinical trials (London, England). 13(3)
Background: The potential impact of missing data on the results of clinical trials has received heightened attention recently. A National Research Council study provides recommendations for limiting missing data in clinical trial design and conduct,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efec16186760de23abff35683fd7692e
https://pubmed.ncbi.nlm.nih.gov/26908543
https://pubmed.ncbi.nlm.nih.gov/26908543
Autor:
Steven M. Snapinn, Leonard Oppenheimer, Valerii V. Fedorov, Chi-Hse Teng, Ivan S.F. Chan, Tom Uryniak, John Zhang, Qi Jiang
Publikováno v:
Statistics in Biopharmaceutical Research. 3:476-487
Ideally, a clinical trial should be able to demonstrate not only a statistically significant improvement in the primary efficacy endpoint, but also that the magnitude of the effect is clinically relevant. One approach to address this question, often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93177ccf16669390fa63e76c8332345c
https://doi.org/10.1198/sbr.2011.10070
https://doi.org/10.1198/sbr.2011.10070
Autor:
Leonard Oppenheimer, Mei Cheng, Rachel Weinstein, Alexei N. Plotnikov, Robert Zolynas, George Griffin, Paul Burton, Zhong Yuan, John Zhang, Mary S. Lee
Publikováno v:
Pharmacoepidemiology and Drug Safety. 19:911-920
SUMMARY Purpose Heart failure is a significant public health problem. The present study is intended to explore in a research database whether antithrombotic therapies (ATTs) affect cardiovascular outcomes in patients with incident heart failure (IHF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac9d84decb7542406d85ae0aea3bc05
https://doi.org/10.1002/pds.1987
https://doi.org/10.1002/pds.1987
Autor:
Troy C, Sarich, Gary, Peters, Scott D, Berkowitz, Frank, Misselwitz, Christopher C, Nessel, Paul, Burton, Nancy, Cook-Bruns, Anthonie W A, Lensing, Lloyd, Haskell, Elisabeth, Perzborn, Dagmar, Kubitza, Kenneth T, Moore, Sanjay, Jalota, Juergen, Weber, Guohua, Pan, Xiang, Sun, Torsten, Westermeier, Andrea, Nadel, Leonard, Oppenheimer, Peter M, DiBattiste
Publikováno v:
Annals of the New York Academy of Sciences. 1291
The development of rivaroxaban (XARELTO®) is an important new medical advance in the field of oral anticoagulation. Thrombosis-mediated conditions constitute a major burden for patients, healthcare systems, and society. For more than 60 years, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6985004b7641761590c4eb6257e4fe39
https://pubmed.ncbi.nlm.nih.gov/23701516
https://pubmed.ncbi.nlm.nih.gov/23701516
Autor:
Zhong, Yuan, Rachel, Weinstein, John, Zhang, Mei, Cheng, George, Griffin, Robert, Zolynas, Alexei N, Plotnikov, Mary S, Lee, Leonard, Oppenheimer, Paul, Burton
Publikováno v:
Pharmacoepidemiology and drug safety. 19(9)
Heart failure is a significant public health problem. The present study is intended to explore in a research database whether antithrombotic therapies (ATTs) affect cardiovascular outcomes in patients with incident heart failure (IHF).Using the Unite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf9aa3fa9dabebc5d4eee6b881bce81a
https://pubmed.ncbi.nlm.nih.gov/20602345
https://pubmed.ncbi.nlm.nih.gov/20602345
Autor:
Uma Kher, Leonard Oppenheimer
Publikováno v:
Statistics in medicine. 18(16)
Investigators often report results of studies comparing the proportions of subjects who have clinically meaningful responses to various therapeutic regimens. When the outcome variable is a continuous measure this involves dichotomizing the observed r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffe7ba9e308f9c982c9ba3c906321e0
https://pubmed.ncbi.nlm.nih.gov/10441772
https://pubmed.ncbi.nlm.nih.gov/10441772
Autor:
C. Conrad Johnston, Ego Seeman, Steven T. Harris, David B. Karpf, Desmond E. Thompson, Arthur C. Santora, Laurence J. Hirsch, Silvano Adami, Leonard Oppenheimer, Kristine E. Ensrud, Deborah R. Shapiro
Publikováno v:
Maturitas. 27:294-295
Objective. —To evaluate the effect of treatment with alendronate sodium, a potent aminobisphosphonate, on the incidence of nonvertebral fractures in postmenopausal women with osteoporosis. Data Sources. —Published data and data on file at Merck R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b64ff379609bda4e531cc1b419657300
https://doi.org/10.1016/s0378-5122(97)11081-7
https://doi.org/10.1016/s0378-5122(97)11081-7
Autor:
Leonard Oppenheimer
Publikováno v:
Statistical Methods in Medical Research. 6:187-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072062e1fba2a2784797490459b8d62a
https://doi.org/10.1177/096228029700600209
https://doi.org/10.1177/096228029700600209
Publikováno v:
Controlled Clinical Trials. 16:93S-94S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f394de06cd94f33030654a51a0128a32
https://doi.org/10.1016/0197-2456(95)90518-a
https://doi.org/10.1016/0197-2456(95)90518-a