Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Leonard L. Firestone"'
Publikováno v:
Anesthesia & Analgesia. 101:449-456
Pain-related cerebral activation in functional magnetic resonance imaging shows less consistent signals that decay earlier than in conventional task-related activation. This may result from pain's top-down inhibition mediated by cognitive or hemodyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb9784205d0d787373eb73dccd01d07
https://doi.org/10.1213/01.ane.0000158468.84424.5d
https://doi.org/10.1213/01.ane.0000158468.84424.5d
Autor:
Randi Albin, Peter S. Staats, Loralie M. Brennen, Geoff A. Green, Leonidas C. Goudas, Mark C Rogers, Philip T Lavin, Leonard L. Firestone, Douglas A. Hamilton, William T. Denman, Daniel Brookoff, Daniel B. Carr, Fred Mermelstein
Publikováno v:
Pain. 108:17-27
Few placebo-controlled trials have investigated the treatment of breakthrough pain (BTP) in patients with chronic pain. We evaluated the efficacy and safety of intranasal ketamine for BTP in a randomized, double-blind, placebo-controlled, crossover t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e4aa9a28c4b8e92e33677dc0792223
https://doi.org/10.1016/j.pain.2003.07.001
https://doi.org/10.1016/j.pain.2003.07.001
Autor:
Leonard L. Firestone, Peter Winter
Publikováno v:
Bulletin of Anesthesia History. 21:15-19
It is unnecessary to describe the horror of surgery prior to the demonstration of ether anaesthesia at Massachusetts General Hospital in 1846. It was clearly a nightmare for patients and must have been little better for the medical personnel involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7b943cb26a2d5dc5a82f3749215c48
https://doi.org/10.1016/s1522-8649(03)50006-3
https://doi.org/10.1016/s1522-8649(03)50006-3
Autor:
Leonard L. Firestone, Gregg E. Homanics, Katherine Jester, Carolyn Ferguson, Joseph J. Quinlan
Publikováno v:
Anesthesia & Analgesia. 95:578-582
UNLABELLED We used two mouse lines with glycine receptor mutations to determine whether glycine receptors might play an important role in anesthetic responses in vivo. Spastic (spA) mutants were slightly more sensitive (P = 0.02) to enflurane in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec8a894b1b0cc05b592d81d97d2864d
https://doi.org/10.1213/00000539-200209000-00016
https://doi.org/10.1213/00000539-200209000-00016
Autor:
Leonard L. Firestone, F. Creed, A. M. Peterson, Stuart W. G. Derbyshire, David W. Townsend, T. Starz, Anthony K. P. Jones, Carolyn C. Meltzer
Publikováno v:
NeuroImage. 16:158-168
Changes in regional cerebral blood flow (rCBF) have previously been demonstrated in a number of cortical and subcortical regions, including the cerebellum, midbrain, thalamus, lentiform nucleus, and the insula, prefrontal, anterior cingulate, and par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc46d0f5508732ddd4c5760538eb9718
https://doi.org/10.1006/nimg.2002.1066
https://doi.org/10.1006/nimg.2002.1066
Publikováno v:
Anesthesiology. 96:35-44
Background Although pain-related activation was localized in multiple brain areas by functional imaging, the temporal profile of its signal has been poorly understood. The authors characterized the temporal evolution of such activation in comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1945f1c534ac8dfad4b73cc8038111ae
https://doi.org/10.1097/00000542-200201000-00012
https://doi.org/10.1097/00000542-200201000-00012
Autor:
Sivam Ramanathan, S. Makishima, Francisco Jaime, Manuel C. Vallejo, Leonard L. Firestone, Gordon L. Mandell
Publikováno v:
Anesthesiology. 95:857-861
Background Ambulatory epidural analgesia (AEA) is a popular choice for labor analgesia because ambulation reportedly increases maternal comfort, increases the intensity of uterine contractions, avoids inferior vena cava compression, facilitates fetal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de67f56fb6d46add7eb2ba71e3a79f8
https://doi.org/10.1097/00000542-200110000-00012
https://doi.org/10.1097/00000542-200110000-00012
Autor:
Leonard L. Firestone, Tomoyoshi Seto
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1509:111-122
The trend of evidence suggests that general anesthetics act directly on proteins in the neural membrane. However, the fact that the functions of nicotinic acetylcholine receptor (sodium permeability, desensitization rate) are modulated by the composi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1876bddcffeac6cc5dced07e5d81a9ad
https://doi.org/10.1016/s0005-2736(00)00285-6
https://doi.org/10.1016/s0005-2736(00)00285-6
Publikováno v:
Psychopharmacology. 145:175-180
Rationale: Previous fluorescence studies employing 1,6-diphenyl-1,3,5-hexatriene (DPH) have revealed an increase in the fluidity of platelet membranes from individuals with Alzheimer’s disease (AD) and their first-degree relatives. This biophysical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a22d772a0485cc8b32365ad84219eb
https://doi.org/10.1007/s002130051046
https://doi.org/10.1007/s002130051046
Autor:
Marco A. Zenati, Richard Holubkov, A.J. Conrad Smith, Howard A. Cohen, Arthur J. Boujoukos, Bartley P. Griffith, Leonard L. Firestone, John Caldwell
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 116(4):584-589
Objective:Available risk assessment models are designed for standard coronary artery bypass grafting. We hypothesized that minimally invasive coronary bypass could improve on predicted outcome in extremely high-risk patients (Parsonnet score > 20%) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769c4997aca1b204f0dd7ef978973bd2