Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Leonard L, Dobens"'
Publikováno v:
Fly, Vol 12, Iss 1, Pp 23-33 (2018)
Epithelial cells are defined by apical-basal and planar cell polarity (PCP) signaling, the latter of which establishes an orthogonal plane of polarity in the epithelial sheet. PCP signaling is required for normal cell migration, differentiation, stem
Externí odkaz:
https://doaj.org/article/f3de14c5f05448bf90f6827fac49876f
Autor:
Zachary Fischer, Rahul Das, Anna Shipman, Jin-Yuan Fan, Laramie Pence, Samuel Bouyain, Leonard L. Dobens
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1453-1464 (2017)
Members of the Tribbles family of proteins are conserved pseudokinases with diverse roles in cell growth and proliferation. Both Drosophila Tribbles (Trbl) and vertebrate Trib3 proteins bind to the kinase Akt (Akt1) to block its phosphorylation activ
Externí odkaz:
https://doaj.org/article/d3c6e48b555d4172866b23378da37140
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109530 (2014)
Drosophila Tribbles (Trbl) is the founding member of the Trib family of kinase-like docking proteins that modulate cell signaling during proliferation, migration and growth. In a wing misexpression screen for Trbl interacting proteins, we identified
Externí odkaz:
https://doaj.org/article/253091a6eefa4f41823f81e8aabce497
Publikováno v:
Fly. 12:23-33
Epithelial cells are defined by apical-basal and planar cell polarity (PCP) signaling, the latter of which establishes an orthogonal plane of polarity in the epithelial sheet. PCP signaling is required for normal cell migration, differentiation, stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53732f8e09c7da6a9f40b04233b4a2d
https://doi.org/10.1080/19336934.2017.1409927
https://doi.org/10.1080/19336934.2017.1409927
Autor:
Kevin Mccormick, Leonard L. Dobens
Publikováno v:
The American Biology Teacher. 79:282-287
Cell migration is a basic developmental function that serves to build tissues, organs, and whole animals. Defects in cell migration are associated with birth defects and cancer, in particular the metastasis of tumors. Over the past forty years resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f4cb247011b2fc6665b627cfc401979
https://doi.org/10.1525/abt.2017.79.4.282
https://doi.org/10.1525/abt.2017.79.4.282
Publikováno v:
Developmental & Comparative Immunology. 64:65-74
Lepidopteran insects constitute one of the largest fractions of animals on earth, but are considered pests in their relationship with man. Key to the success of this order of insects is its ability to digest food and absorb nutrition, which takes pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d6b1a49d1f70361dc58d05efb56018
https://doi.org/10.1016/j.dci.2016.02.010
https://doi.org/10.1016/j.dci.2016.02.010
Autor:
Takuro Nakamura, Robert C. Bauer, Marcel Scheideler, Shan-Shan Liu, Xiaoxi Lv, Nguan Soon Tan, Dominika Grzesik, Ji-Chao Zhou, Endre Kiss-Toth, Yodit Feseha, Yishi Jin, Fang Hua, Shuang Shang, Warren S. Pear, Ke Li, Jessica Johnston, Jin-mei Yu, Patrick A. Eyers, Leonard L. Dobens, Peter D. Mace, Guillermo Velasco, Juan Salamanca-Viloria, Wolfgang Link, Feng Wang, Xiaowei Zhang, Jose M. Lizcano, Jiao-jiao Yu, Jorge D. Erusalimsky, Zabran llyas, Zhuo-Wei Hu, Bing Cui, Arkatiz Carracedo, Karen Keeshan
Publikováno v:
Acta Pharm. Sin. B 9, 443-454 (2019)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Acta Pharmaceutica Sinica B
Addi. Archivo Digital para la Docencia y la Investigación
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Acta Pharmaceutica Sinica B
The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle, metabolic diseases, chronic inflammatory disease, and cancer development. A better understanding of the mechanisms of TRIB pseudokinases could provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201c87f13b3c7a3dca0a6221bd738c2b
http://hdl.handle.net/10810/32925
http://hdl.handle.net/10810/32925
Drosophila Tribbles (Trbl) is the founding member of a family of pseudokinases with conserved roles in antagonizing cell division, tissue growth and cell differentiation. In humans, three Tribbles isoforms serve as adaptor proteins, binding targets s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d64d37394c82ef37175f0f8103f9cb
Autor:
Zachary, Fischer, Rahul, Das, Anna, Shipman, Jin-Yuan, Fan, Laramie, Pence, Samuel, Bouyain, Leonard L, Dobens
Publikováno v:
Disease Models & Mechanisms
Members of the Tribbles family of proteins are conserved pseudokinases with diverse roles in cell growth and proliferation. Both Drosophila Tribbles (Trbl) and vertebrate Trib3 proteins bind to the kinase Akt (Akt1) to block its phosphorylation activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd545613be2af071b443f14315830ca1
https://pubmed.ncbi.nlm.nih.gov/29025897
https://pubmed.ncbi.nlm.nih.gov/29025897