Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Leonard Jurd"'
Autor:
Leonard Jurd
Publikováno v:
Journal of Heterocyclic Chemistry. 34:601-604
2-Aminopyridine, sesamol and 4-hydroxy-3,5-dimethoxybenzaldehyde condense to form a Mannicb base 3b which reacts with tetronic acid to yield lactone 4c. Cyclization of 4c yields the benzopyran lactone 1b; this inhibits growth of tumors in NCI in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8607d3590adacaf3d0946b60cc5ef4
https://doi.org/10.1002/jhet.5570340242
https://doi.org/10.1002/jhet.5570340242
Autor:
Leonard Jurd
Publikováno v:
Journal of Heterocyclic Chemistry. 33:1919-1925
Pyrrolidine, morpholine and piperidine derived Mannich bases of types 1–3 react with acetone, propionaldehyde and butyraldehyde to form 2-methyl and 3-methylbenzopyrans of types 4–8. Hydrolysis of these benzopyrans yields alcoholic benzopyrans wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a0cd0fdd0918a53cc8a34dcbfd4e42
https://doi.org/10.1002/jhet.5570330660
https://doi.org/10.1002/jhet.5570330660
Autor:
Leonard Jurd
Publikováno v:
Journal of Heterocyclic Chemistry. 33:1227-1232
Morpholino Mannich bases of types 5, 12 react with tetronic acid in aqueous acetic acid to yield uncyclized lactones of types 7, 13. Acetylation and methylation of these products yields monoacetyl-monomethyl derivatives which can then be cyclized in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c7d7fffe90dff079dcc3df701cb9281
https://doi.org/10.1002/jhet.5570330438
https://doi.org/10.1002/jhet.5570330438
Publikováno v:
Archives of Insect Biochemistry and Physiology. 27:39-51
Alkyl ethers of methylenedioxy analogs of obtusastyrene or benzyl-1,3-benzodioxole derivatives (BBDs) and related benzylphenols have been shown to interfere with various phases of reproduction in insects. BBDs have also been shown to interfere with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bde7e5eeac16ce4284821d923ce6b6f
https://doi.org/10.1002/arch.940270106
https://doi.org/10.1002/arch.940270106
Publikováno v:
Journal of Medicinal Chemistry. 35:1058-1067
A number of cytostatic compounds (2-4, 7, and 8), which can be described as "diaryl", inhibit tubulin polymerization, cause cells to accumulate in mitotic arrest, and competitively inhibit the binding of colchicine to tubulin. They differ, however, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a7969e8990463b14c38b774fa9526b
https://doi.org/10.1021/jm00084a011
https://doi.org/10.1021/jm00084a011
Autor:
Leonard Jurd
Publikováno v:
Journal of Heterocyclic Chemistry. 28:983-986
Sesamol and other phenols react with equimolar quantities of cinnamaldehyde and morpholine in methanol to yield epimeric 2-morpholinyl-4-phenylbenzopyran derivatives, which are useful intermediates for the synthesis of alcoholic neoflavanoid (4-pheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ae6f5507eb8f1e22f4de52b2fcfd304
https://doi.org/10.1002/jhet.5570280424
https://doi.org/10.1002/jhet.5570280424
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 99:15-20
1. Competitive displacement assays showed the presence of a single saturable high-affinity binder for JH III in hemolymph from adult female C . capitata . 2. The dissociation constant K d and total binding capacity B max for the binder were 0.93 × 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6914c390ff31e04ecfa2da5c9673447b
https://doi.org/10.1016/0742-8413(91)90068-5
https://doi.org/10.1016/0742-8413(91)90068-5
Publikováno v:
Journal of Economic Entomology. 83:1261-1266
Prepupae of the oriental fruit fly, Dacus dorsalis , Hendel, were exposed to topsoil treated with a benzyl-l,3-benzodioxole derivative (BBD), J2581 (5-ethoxy-6-[4-methoxyphenyl] methyl-l,3-benzodioxole). At a concentration range of 0.83-13.20 mg J258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5481e83c63f82d4d7207bf281d0317
https://doi.org/10.1093/jee/83.4.1261
https://doi.org/10.1093/jee/83.4.1261
Autor:
Leonard Jurd
Publikováno v:
ChemInform. 21
Mannich bases of types 1 or 8, which are readily synthesized by condensation of 3,4-methylenedioxyphenol with aromatic aldehydes and pyrrolidine or piperazine, react with cyclic and acyclic β-diketones to yield benzopyrans. These benzopyrans are str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f9a222b388b34f36c474c4175f5bce0
https://doi.org/10.1002/chin.199011341
https://doi.org/10.1002/chin.199011341
Autor:
Leonard Jurd, James N. Roitman
Publikováno v:
Tetrahedron. 35:1567-1574
In strongly acid solutions the dimer 3 dissociates to the quinone 1 and quinone methide 2 which recombine with elimination of p -methoxybenzyl alcohol to form the xanthylium salt 9a . With zinc and acetic acid 3 yields isormeric meso- and dl-ethylene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffb16eb69a41144fd9a1b6ffa87d0ba1
https://doi.org/10.1016/0040-4020(79)80017-4
https://doi.org/10.1016/0040-4020(79)80017-4